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Property, Plant and Equipment, Net | 6 Months Ended
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Jun. 30, 2024
Property, Plant and Equipment [Abstract] |
Property, Plant and Equipment, Net | 8. Property, Plant and Equipment, Net Property, plant and equipment, net, as of June 30, 2024 and December 31, 2023 consisted of the following (in millions):
|  | June 30, |  | December 31,
|  | 2024 |  | 2023
Land and land improvements |  | $ | 22 |  |  | $ | 22 |
Manufacturing and laboratory equipment |  | 355 |  |  | 345 |
Leasehold improvements |  | 664 |  |  | 522 |
Furniture, fixtures and other |  | 33 |  |  | 26 |
Computer equipment and software |  | 136 |  |  | 74 |
Construction in progress |  | 961 |  |  | 860 |
Right-of-use assets, financing (Note 10) |  | 529 |  |  | 529 |
Total |  | 2,700 |  |  | 2,378 |
Less: Accumulated depreciation |  | (504) |  |  | (433) |
Property, plant and equipment, net |  | $ | 2,196 |  |  | $ | 1,945 |
Depreciation and amortization expense for three and six months ended June 30, 2024 was $40 million and $75 million, respectively. Depreciation and amortization expense for the three and six months ended June 30, 2023 was $90 million and $168 million, respectively.

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- Definition The entire disclosure for long-lived, physical asset used in normal conduct of business and not intended for resale. Includes, but is not limited to, work of art, historical treasure, and similar asset classified as collections. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 360 -Name Accounting Standards Codification -Publisher FASB -URI https://asc.fasb.org/360/tableOfContent Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Name Accounting Standards Codification -Section 50 -Paragraph 6 -SubTopic 360 -Topic 958 -Publisher FASB -URI https://asc.fasb.org/1943274/2147477798/958-360-50-6 Reference 3: http://www.xbrl.org/2003/role/disclosureRef -Name Accounting Standards Codification -Section 50 -Paragraph 1 -Subparagraph (d) -SubTopic 360 -Topic 958 -Publisher FASB -URI https://asc.fasb.org/1943274/2147477798/958-360-50-1 Reference 4: http://www.xbrl.org/2003/role/disclosureRef -Name Accounting Standards Codification -Section 50 -Paragraph 7 -SubTopic 360 -Topic 958 -Publisher FASB -URI https://asc.fasb.org/1943274/2147477798/958-360-50-7 + Details
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