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CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($)
shares in Millions, $ in Millions
 3 Months Ended 6 Months Ended
Jun. 30, 2024
Jun. 30, 2023
Jun. 30, 2024
Jun. 30, 2023
Revenue:        
Total revenue $ 241 $ 344 $ 408 $ 2,206
Operating expenses:        
Cost of sales 115 731 211 1,523
Research and development 1,221 1,148 2,284 2,279
Selling, general and administrative 268 332 542 637
Total operating expenses 1,604 2,211 3,037 4,439
Loss from operations (1,363) (1,867) (2,629) (2,233)
Interest income 111 104 231 213
Other (expense) income, net (27) 14 (46) (34)
Loss before income taxes (1,279) (1,749) (2,444) (2,054)
Provision for (benefit from) income taxes 0 (369) 10 (753)
Net loss $ (1,279) $ (1,380) $ (2,454) $ (1,301)
Net loss per share:        
Basic (in usd per share) $ (3.33) $ (3.62) $ (6.41) $ (3.39)
Diluted (in usd per share) $ (3.33) $ (3.62) $ (6.41) $ (3.39)
Weighted average common shares used in calculation of net loss per share:        
Basic (in shares) 384 381 383 383
Diluted (in shares) 384 381 383 383
Net product sales        
Revenue:        
Total revenue $ 184 $ 293 $ 351 $ 2,121
Other revenue        
Revenue:        
Total revenue $ 57 $ 51 $ 57 $ 85