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Collaboration Agreements and Research and Development Funding Arrangement (Details) - USD ($)
$ in Millions
3 Months Ended 6 Months Ended
Jun. 30, 2024
Jun. 30, 2023
Jun. 30, 2024
Jun. 30, 2023
Mar. 31, 2024
Oct. 31, 2022
Research and Development Arrangement, Contract to Perform for Others [Line Items]            
Research and development $ 1,221 $ 1,148 $ 2,284 $ 2,279    
Merck | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement            
Research and Development Arrangement, Contract to Perform for Others [Line Items]            
Cash proceeds           $ 250
Research and development 95 50 171 69    
Recovery of costs $ 33 $ 12 $ 57 $ 18    
Blackstone Life Sciences (Blackstone) | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement            
Research and Development Arrangement, Contract to Perform for Others [Line Items]            
Funding amount         $ 750  
Milestone payments         $ 750