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Other Balance Sheet Components - Accrued Liabilities (Details) - USD ($) $ in Millions | Dec. 31, 2025 | Dec. 31, 2024
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Organization, Consolidation and Presentation of Financial Statements [Abstract] |  |
Provisions related to product sales (Note 3) | $ 509 | $ 370
Compensation-related | 420 | 312
Manufacturing | 140 | 109
Development operations | 106 | 120
Other external goods and services | 57 | 131
Property, plant and equipment | 45 | 99
Royalties | 31 | 46
Raw materials | 30 | 41
Commercial | 23 | 45
Clinical trials | 20 | 94
Loss on future firm purchase commitments | 5 | 60
Accrued liabilities | $ 1,386 | $ 1,427

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- Definition Carrying value as of the balance sheet date of obligations incurred and payable, pertaining to costs that are statutory in nature, are incurred on contractual obligations, or accumulate over time and for which invoices have not yet been received or will not be rendered. Examples include taxes, interest, rent and utilities. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer). + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 210 -SubTopic 10 -Name Accounting Standards Codification -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02(20)) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480566/210-10-S99-1 + Details
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