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v3.25.4

Property, Plant and Equipment, Net | 12 Months Ended
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Dec. 31, 2025
Property, Plant and Equipment [Abstract] |
Property, Plant and Equipment, Net | 8. Property, Plant and Equipment, Net Property, plant and equipment, net as of December 31, 2025 and 2024 consisted of the following (in millions):
|  | December 31,
|  | 2025 |  | 2024 |  |
Land and land improvements |  | $ | 78 |  |  | $ | 59 |  |  |
Building and building improvements |  | 1,183 |  |  | 743 |  |  |
Manufacturing and laboratory equipment |  | 542 |  |  | 344 |  |  |
Leasehold improvements |  | 403 |  |  | 207 |  |  |
Furniture, fixtures and other |  | 39 |  |  | 31 |  |  |
Computer equipment and software |  | 196 |  |  | 150 |  |  |
Construction in progress |  | 298 |  |  | 1,057 |  |  |
Right-of-use assets, financing (Note 10) |  | 132 |  |  | 132 |  |  |
Total |  | 2,871 |  |  | 2,723 |  |  |
Less: Accumulated depreciation |  | (737) |  |  | (527) |  |  |
Property, plant and equipment, net |  | $ | 2,134 |  |  | $ | 2,196 |  |  |
Depreciation and amortization expense for the years ended December 31, 2025, 2024, and 2023 was $211 million, $185 million, and $617 million, respectively.

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- Definition The entire disclosure for long-lived, physical asset used in normal conduct of business and not intended for resale. Includes, but is not limited to, work of art, historical treasure, and similar asset classified as collections. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 360 -Name Accounting Standards Codification -Publisher FASB -URI https://asc.fasb.org/360/tableOfContent Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Name Accounting Standards Codification -Section 50 -Paragraph 6 -SubTopic 360 -Topic 958 -Publisher FASB -URI https://asc.fasb.org/1943274/2147477798/958-360-50-6 Reference 3: http://www.xbrl.org/2003/role/disclosureRef -Name Accounting Standards Codification -Section 50 -Paragraph 1 -Subparagraph (d) -SubTopic 360 -Topic 958 -Publisher FASB -URI https://asc.fasb.org/1943274/2147477798/958-360-50-1 Reference 4: http://www.xbrl.org/2003/role/disclosureRef -Name Accounting Standards Codification -Section 50 -Paragraph 7 -SubTopic 360 -Topic 958 -Publisher FASB -URI https://asc.fasb.org/1943274/2147477798/958-360-50-7 + Details
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