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v3.25.4

Property, Plant and Equipment, Net (Details) - USD ($) $ in Millions | 12 Months Ended
--- | ---
Dec. 31, 2025 | Dec. 31, 2024 | Dec. 31, 2023
Property, Plant and Equipment [Line Items] |  |  |
Property and equipment, gross | $ 2,871 | $ 2,723 |
Less: Accumulated depreciation | (737) | (527) |
Property, plant and equipment, net | 2,134 | 2,196 |
Depreciation and amortization | 211 | 185 | $ 617
Land and land improvements |  |  |
Property, Plant and Equipment [Line Items] |  |  |
Property and equipment, gross | 78 | 59 |
Building and building improvements |  |  |
Property, Plant and Equipment [Line Items] |  |  |
Property and equipment, gross | 1,183 | 743 |
Manufacturing and laboratory equipment |  |  |
Property, Plant and Equipment [Line Items] |  |  |
Property and equipment, gross | 542 | 344 |
Leasehold improvements |  |  |
Property, Plant and Equipment [Line Items] |  |  |
Property and equipment, gross | 403 | 207 |
Furniture, fixtures and other |  |  |
Property, Plant and Equipment [Line Items] |  |  |
Property and equipment, gross | 39 | 31 |
Computer equipment and software |  |  |
Property, Plant and Equipment [Line Items] |  |  |
Property and equipment, gross | 196 | 150 |
Construction in progress |  |  |
Property, Plant and Equipment [Line Items] |  |  |
Property and equipment, gross | 298 | 1,057 |
Right-of-use assets, financing |  |  |
Property, Plant and Equipment [Line Items] |  |  |
Property and equipment, gross | $ 132 | $ 132 |

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