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Property, Plant and Equipment, Net (Tables)
 12 Months Ended
Dec. 31, 2025
Property, Plant and Equipment [Abstract]  
Schedule of Property, Plant and Equipment, Net The estimated useful lives of property, plant and equipment are described below:
Estimated Useful Life
Land and permanent land improvements
Not depreciated
Limited-life land improvements
Determined on a project-by-project basis
Buildings and building improvements
Up to 40 years
Manufacturing and laboratory equipment
5-12 years
Leasehold improvements
Lesser of estimated useful life of improvement
or remaining life of related lease
Computer equipment and software
3 to 5 years
Furniture, fixtures and other
5 years
Right-of-use asset, financingLease term
Property, plant and equipment, net as of December 31, 2025 and 2024 consisted of the following (in millions):
December 31,
20252024
Land and land improvements$78 $59 
Building and building improvements1,183 743 
Manufacturing and laboratory equipment542 344 
Leasehold improvements403 207 
Furniture, fixtures and other
39 31 
Computer equipment and software
196 150 
Construction in progress
298 1,057 
Right-of-use assets, financing (Note 10)
132 132 
Total
2,871 2,723 
Less: Accumulated depreciation
(737)(527)
Property, plant and equipment, net$2,134 $2,196