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Geographic Information (Tables)
 12 Months Ended
Dec. 31, 2025
Revenue from Contract with Customer [Abstract]  
Schedule of Revenue from External Customers by Geographic Areas
Net product sales by customer geographic location were as follows for the periods presented (in millions):
Years Ended December 31,
202520242023
United States$1,165 $1,726 $1,720 
Europe50 573 1,353 
Rest of world
603 810 3,598 
Total $1,818 $3,109 $6,671 
Total revenue by geographic area of our customers and collaborators was as follows (in millions):
Years Ended December 31,
202520242023
United States$1,199 $1,785 $1,895 
Europe53 598 1,355 
Rest of world
692 853 3,598 
Total $1,944 $3,236 $6,848 

Our property, plant and equipment, including financing right-of-use assets, by geographic area was as follows (in millions):
December 31,
20252024
United States$1,468 $1,532 
Europe303 283 
Rest of world363 381 
Total$2,134 $2,196