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Net Product Sales - Net Product Sales by Customer Geographic Areas (Details) - USD ($)
$ in Millions
 12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Disaggregation of Revenue [Line Items]      
Total revenue $ 1,944 $ 3,236 $ 6,848
Net product sales      
Disaggregation of Revenue [Line Items]      
Total revenue 1,818 3,109 6,671
COVID      
Disaggregation of Revenue [Line Items]      
Total revenue 1,810 3,084 6,671
RSV      
Disaggregation of Revenue [Line Items]      
Total revenue 8 25 0
United States      
Disaggregation of Revenue [Line Items]      
Total revenue 1,199 1,785 1,895
United States | Net product sales      
Disaggregation of Revenue [Line Items]      
Total revenue 1,165 1,726 1,720
Europe      
Disaggregation of Revenue [Line Items]      
Total revenue 53 598 1,355
Europe | Net product sales      
Disaggregation of Revenue [Line Items]      
Total revenue 50 573 1,353
Rest of world | Net product sales      
Disaggregation of Revenue [Line Items]      
Total revenue $ 603 $ 810 $ 3,598