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Other Balance Sheet Components - Accrued Liabilities (Details) - USD ($) $ in Millions	Dec. 31, 2025	Dec. 31, 2024
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Provisions related to product sales (Note 3)	$ 509	$ 370
Compensation-related	420	312
Manufacturing	140	109
Development operations	106	120
Other external goods and services	57	131
Property, plant and equipment	45	99
Royalties	31	46
Raw materials	30	41
Commercial	23	45
Clinical trials	20	94
Loss on future firm purchase commitments	5	60
Accrued liabilities	$ 1,386	$ 1,427

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Accrued Clinical Trials

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Accrued Commercial

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Accrued Development Operation

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Accrued Manufacturing

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Accrued Property And Equipment, Current

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Legal Contingency, Future Firm Purchase Commitments

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Raw Materials, Accounts Payable

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Carrying value as of the balance sheet date of obligations incurred and payable, pertaining to costs that are statutory in nature, are incurred on contractual obligations, or accumulate over time and for which invoices have not yet been received or will not be rendered. Examples include taxes, interest, rent and utilities. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).

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Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Topic 210
-SubTopic 10
-Name Accounting Standards Codification
-Section S99
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-Publisher FASB
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Carrying value as of the balance sheet date of obligations incurred through that date and payable for royalties. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).

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Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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-Name Accounting Standards Codification
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Amount of liability for consideration received or receivable from customer which is not included in transaction price, when consideration is expected to be refunded to customer.

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Total of the carrying values as of the balance sheet date of obligations incurred through that date and payable for obligations related to services received from employees, such as accrued salaries and bonuses, payroll taxes and fringe benefits. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).

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