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Collaboration Agreements and Research and Development Funding Arrangement (Details) - USD ($) $ in Millions | 3 Months Ended |  |  |
--- | --- | --- | --- | ---
Mar. 31, 2026 | Mar. 31, 2025 | Mar. 16, 2026 | Mar. 31, 2024 | Oct. 31, 2022
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |
Research and development | $ 649.0 | $ 856.0 |  |  |
Additions | 53.0 |  |  |  |
Merck | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement |  |  |  |  |
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |
Cash proceeds |  |  |  |  | $ 250.0
Research and development | 101.0 | 104.0 |  |  |
Recovery of costs | 1.0 | 12.0 |  |  |
Recordati S.p.A | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement |  |  |  |  |
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |
Funding amount |  |  | $ 50.0 |  |
Milestone payment |  |  | $ 110.0 |  |
Blackstone Life Sciences (Blackstone) | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement |  |  |  |  |
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |
Research and development | $ 50.0 | $ 90.0 |  |  |
Funding amount |  |  |  | $ 750.0 |
Milestone payment |  |  |  | $ 750.0 |

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