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Collaboration Agreements and Research and Development Funding Arrangement (Details) - USD ($)
$ in Millions
3 Months Ended
Mar. 31, 2026
Mar. 31, 2025
Mar. 16, 2026
Mar. 31, 2024
Oct. 31, 2022
Research and Development Arrangement, Contract to Perform for Others [Line Items]          
Research and development $ 649.0 $ 856.0      
Additions 53.0        
Merck | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement          
Research and Development Arrangement, Contract to Perform for Others [Line Items]          
Cash proceeds         $ 250.0
Research and development 101.0 104.0      
Recovery of costs 1.0 12.0      
Recordati S.p.A | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement          
Research and Development Arrangement, Contract to Perform for Others [Line Items]          
Funding amount     $ 50.0    
Milestone payment     $ 110.0    
Blackstone Life Sciences (Blackstone) | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement          
Research and Development Arrangement, Contract to Perform for Others [Line Items]          
Research and development $ 50.0 $ 90.0      
Funding amount       $ 750.0  
Milestone payment       $ 750.0