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Other Balance Sheet Components - Schedule of Accrued Liabilities (Details) - USD ($)
$ in Millions
Mar. 31, 2026
Dec. 31, 2025
Organization, Consolidation and Presentation of Financial Statements [Abstract]    
Royalties $ 967 $ 31
Provisions related to product sales (Note 3) 470 509
Compensation-related 108 420
Other external goods and services 82 57
Development operations 81 106
Manufacturing 79 140
Clinical trials 46 20
Property, plant and equipment 31 45
Raw materials 27 30
Commercial 16 23
Loss on future firm purchase commitments 5 5
Accrued liabilities 1,912 $ 1,386
Litigation settlement liability $ 950