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Balance Sheet Components - Property and Equipment (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2024	Dec. 31, 2023	Dec. 31, 2022
Property, Plant and Equipment, Net [Abstract]
Property and equipment	$ 1,932,846	$ 1,841,625
Less: Accumulated depreciation and impairment charges	(661,712)	(550,762)
Total property, plant and equipment, net	1,271,134	1,290,863
Depreciation	126,200	126,000	$ 109,800
Clinical and manufacturing equipment
Property, Plant and Equipment, Net [Abstract]
Property and equipment	$ 871,827	703,805
Building
Property, Plant and Equipment [Line Items]
Estimated useful life	20 years
Property, Plant and Equipment, Net [Abstract]
Property and equipment	$ 529,716	517,554
Leasehold improvements
Property, Plant and Equipment, Net [Abstract]
Property and equipment	$ 62,172	125,633
Computer software and hardware
Property, Plant and Equipment [Line Items]
Estimated useful life	3 years
Property, Plant and Equipment, Net [Abstract]
Property and equipment	$ 135,756	62,216
Land
Property, Plant and Equipment, Net [Abstract]
Property and equipment	63,875	63,875
Furniture, fixtures and other
Property, Plant and Equipment, Net [Abstract]
Property and equipment	135,816	122,820
Construction in progress
Property, Plant and Equipment, Net [Abstract]
Property and equipment	$ 133,684	$ 245,722
Minimum | Furniture, fixtures and other
Property, Plant and Equipment [Line Items]
Estimated useful life	2 years
Maximum | Clinical and manufacturing equipment
Property, Plant and Equipment [Line Items]
Estimated useful life	13 years
Maximum | Furniture, fixtures and other
Property, Plant and Equipment [Line Items]
Estimated useful life	5 years

X

- Definition

Amount of accumulated depreciation, depletion and amortization for physical assets used in the normal conduct of business to produce goods and services.

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- Definition

The amount of expense recognized in the current period that reflects the allocation of the cost of tangible assets over the assets' useful lives. Includes production and non-production related depreciation.

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Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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Amount after accumulated depreciation, depletion and amortization of physical assets used in the normal conduct of business to produce goods and services and not intended for resale. Examples include, but are not limited to, land, buildings, machinery and equipment, office equipment, and furniture and fixtures.

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Useful life of long lived, physical assets used in the normal conduct of business and not intended for resale, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days. Examples include, but not limited to, land, buildings, machinery and equipment, office equipment, furniture and fixtures, and computer equipment.

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