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Significant agreements (Details)
$ in Thousands
1 Months Ended 12 Months Ended
Mar. 31, 2022
USD ($)
tradingDay
Dec. 31, 2023
USD ($)
Jun. 09, 2021
USD ($)
Ligand UK Development Limited      
Capitalized Contract Cost [Line Items]      
Sublicense Payment $ 2,000    
Sublicense Payment, Equity Issuance, Threshold Trading Days | tradingDay 10    
Ligand UK Development Limited | Selling, General and Administrative Expenses      
Capitalized Contract Cost [Line Items]      
Sublicense Payment $ 2,000    
Ligand UK Development Limited | First Commercial Sale      
Capitalized Contract Cost [Line Items]      
Sublicense Payment $ 15,000    
Nuance (Shanghai) Pharma Co Ltd      
Capitalized Contract Cost [Line Items]      
Transaction price     $ 40,000
Accounts receivable     25,000
Equity interest receivable   $ 15,000 15,000
Future eligible milestone payments     $ 179,000
Contract with Customer, Liability, Revenue Recognized   $ 500