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Consolidated Statements of Shareholders’ Equity - USD ($)
$ in Thousands
Total
At-The-Market Sales Agreement
Ordinary shares
Ordinary shares
At-The-Market Sales Agreement
Additional paid-in capital
Additional paid-in capital
At-The-Market Sales Agreement
Ordinary shares held in treasury
Accumulated other comprehensive loss
Accumulated deficit
Beginning balance (in shares) at Dec. 31, 2022     631,338,246            
Beginning balance at Dec. 31, 2022 $ 230,466   $ 40,526   $ 529,187   $ (1,549) $ (4,601) $ (333,097)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                  
Net loss (16,743)               (16,743)
Issuance of common shares (in shares)       20,321,384          
Issuance of common shares   $ 56,909   $ 1,227   $ 55,682      
Restricted share units vested             270   (270)
Share options exercised 1,827       1,756   71    
Share-based compensation 4,290       4,290        
Ending balance (in shares) at Mar. 31, 2023     651,659,630            
Ending balance at Mar. 31, 2023 276,749   $ 41,753   590,915   (1,208) (4,601) (350,110)
Beginning balance (in shares) at Dec. 31, 2022     631,338,246            
Beginning balance at Dec. 31, 2022 230,466   $ 40,526   529,187   (1,549) (4,601) (333,097)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                  
Net loss (40,237)                
Ending balance (in shares) at Sep. 30, 2023     651,659,630            
Ending balance at Sep. 30, 2023 263,533   $ 41,753   601,180   (746) (4,601) (374,053)
Beginning balance (in shares) at Mar. 31, 2023     651,659,630            
Beginning balance at Mar. 31, 2023 276,749   $ 41,753   590,915   (1,208) (4,601) (350,110)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                  
Net loss (8,807)               (8,807)
Restricted share units vested             226   (226)
Share options exercised 77       70   7    
Share-based compensation 5,074       5,074        
Ending balance (in shares) at Jun. 30, 2023     651,659,630            
Ending balance at Jun. 30, 2023 273,093   $ 41,753   596,059   (975) (4,601) (359,143)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                  
Net loss (14,687)               (14,687)
Restricted share units vested             223   (223)
Share options exercised 48       42   6    
Share-based compensation 5,079       5,079        
Ending balance (in shares) at Sep. 30, 2023     651,659,630            
Ending balance at Sep. 30, 2023 $ 263,533   $ 41,753   601,180   (746) (4,601) (374,053)
Beginning balance (in shares) at Dec. 31, 2023 643,536,094   667,659,630            
Beginning balance at Dec. 31, 2023 $ 249,283   $ 42,771   601,063   (1,517) (4,601) (388,433)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                  
Net loss (25,794)               (25,794)
Restricted share units vested             170   (170)
Share options exercised 816       751   65    
Common shares withheld for taxes on vested stock awards (3,338)       (3,338)        
Equity settled share-based compensation reclassified as cash-settled (237)       (237)        
Share-based compensation 4,258       4,258        
Ending balance (in shares) at Mar. 31, 2024     667,659,630            
Ending balance at Mar. 31, 2024 $ 224,988   $ 42,771   602,497   (1,282) (4,601) (414,397)
Beginning balance (in shares) at Dec. 31, 2023 643,536,094   667,659,630            
Beginning balance at Dec. 31, 2023 $ 249,283   $ 42,771   601,063   (1,517) (4,601) (388,433)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                  
Net loss $ (139,591)                
Ending balance (in shares) at Sep. 30, 2024 654,649,358   667,659,630            
Ending balance at Sep. 30, 2024 $ 130,491   $ 42,771   621,628   (828) (4,601) (528,479)
Beginning balance (in shares) at Jun. 30, 2024     667,659,630            
Beginning balance at Jun. 30, 2024 168,274   $ 42,771   616,618   (1,203) (4,601) (485,311)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                  
Net loss (42,962)               (42,962)
Restricted share units vested             206   (206)
Share options exercised 3,668       3,499   169    
Common shares withheld for taxes on vested stock awards (5,600)       (5,600)        
Equity settled share-based compensation reclassified as cash-settled (543)       (543)        
Share-based compensation $ 7,654       7,654        
Ending balance (in shares) at Sep. 30, 2024 654,649,358   667,659,630            
Ending balance at Sep. 30, 2024 $ 130,491   $ 42,771   $ 621,628   $ (828) $ (4,601) $ (528,479)