Exhibit 16.1
August 10, 2022
Securities and Exchange Commission
100 F Street, N.E.
Washington, DC 20549
Commissioners:
We have read the statements made by D-Wave Quantum Inc. under Item 4.01 of its Form 8-K filed August 10, 2022. We agree with the statements concerning our Firm under Item 4.01 of such Form 8-K; we are not in a position to agree or disagree with other statements of D-Wave Quantum Inc. contained therein.
| Very truly yours, |
| /s/ Marcum LLP |
| Marcum LLP |