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Consolidated Statements of Stockholders’ Equity (Deficit) - USD ($)
$ in Thousands
Total
Lincoln Park Purchase Agreement
At-the-Market Offering
Common stock
Common stock
Lincoln Park Purchase Agreement
Common stock
At-the-Market Offering
Additional paid-in capital
Additional paid-in capital
Lincoln Park Purchase Agreement
Additional paid-in capital
At-the-Market Offering
Accumulated deficit
Accumulated other comprehensive loss
Beginning balance (in shares) at Dec. 31, 2022       113,335,530              
Beginning balance at Dec. 31, 2022 $ (29,463)     $ 11     $ 381,274     $ (400,346) $ (10,402)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                      
Issuance of common stock in connection with the Purchase Agreement/ATM agreement, net of issuance costs (in shares)       42,147,838              
Issuance of common stock in connection with the Purchase Agreement/ATM agreement, net of issuance costs 63,676     $ 4     63,672        
Issuance of common stock in connection with the Employee Stock Purchase Plan (in shares)       467,388              
Issuance of common stock in connection with the Employee Stock Purchase Plan 491           491        
Exercise of stock options (in shares)       5,162,988              
Exercise of stock options 1,898     $ 1     1,897        
Stock-based compensation 21,919           21,919        
Tax withholding related to vesting of restricted stock units (416)           (416)        
Short-swing profit settlement 244           244        
Foreign currency translation adjustment, net of tax (115)                   (115)
Net loss $ (82,715)                 (82,715)  
Ending balance (in shares) at Dec. 31, 2023 161,113,744     161,113,744              
Ending balance at Dec. 31, 2023 $ (24,481)     $ 16     469,081     (483,061) (10,517)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                      
Issuance of common stock in connection with the Purchase Agreement/ATM agreement, net of issuance costs (in shares)         34,860,416 65,388,915          
Issuance of common stock in connection with the Purchase Agreement/ATM agreement, net of issuance costs   $ 44,285 $ 169,906   $ 3 $ 7   $ 44,282 $ 169,899    
Issuance of common stock in connection with the Employee Stock Purchase Plan (in shares)       487,782              
Issuance of common stock in connection with the Employee Stock Purchase Plan 425           424        
Issuance of common stock in connection with exercise of stock options and vesting of RSUs (in shares)       4,745,010              
Issuance of common stock in connection with exercise of stock options and vesting of RSUs $ 1,724           1,724        
Exercise of stock options (in shares) 1,911,119                    
Stock-based compensation $ 17,801           17,801        
Tax withholding related to vesting of restricted stock units (3,142)           (3,142)        
Foreign currency translation adjustment, net of tax 7                   7
Net loss $ (143,879)                 (143,879)  
Ending balance (in shares) at Dec. 31, 2024 266,595,867     266,595,867              
Ending balance at Dec. 31, 2024 $ 62,646     $ 27     $ 700,069     $ (626,940) $ (10,510)