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Summary of Significant Accounting Policies (Tables)
3 Months Ended
Mar. 31, 2025
Accounting Policies [Abstract]  
Schedule of Significant Segment Expenses

In addition to the significant expense categories included within consolidated net loss presented on the Company’s condensed consolidated statements of operations, see below for disaggregated amounts that comprise research and development expenses:

 

 

 

As of March 31,

 

 

 

2025

 

 

2024

 

 

 

(in thousands)

 

Third-party research and development expenses(a)

 

$

132,743

 

 

$

69,270

 

Salaries and other employee-related expenses

 

 

37,194

 

 

 

25,163

 

Stock-based compensation expense

 

 

16,380

 

 

 

10,244

 

Amortization of intangible assets

 

 

267

 

 

 

267

 

Other research and development costs

 

 

19,165

 

 

 

13,077

 

Total research and development expense

 

$

205,749

 

 

$

118,021

 

(a) Third-party research and development expenses are comprised primarily of external costs incurred under agreements with third-party contract organizations, investigative clinical trial sites that conduct research and development activities on the Company’s behalf and consultants; costs related to the production of preclinical, clinical and pre-launch materials, including fees paid to contract manufacturers; and laboratory and vendor expenses related to the execution of discovery programs, preclinical and clinical trials.