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Organization - Additional Information (Details) - USD ($)
$ / shares in Units, $ in Thousands
 1 Months Ended 12 Months Ended
Aug. 31, 2024
Nov. 30, 2021
Dec. 31, 2024
Mar. 31, 2025
Class Of Stock [Line Items]        
Accumulated deficit     $ (1,737,801) $ (1,951,217)
Common stock, shares, issued     185,896,625 186,258,206
Underwriter's Option to Purchase Additional Shares        
Class Of Stock [Line Items]        
Common stock, shares, issued     2,445,652  
Underwritten Public Offering        
Class Of Stock [Line Items]        
Common stock, shares, issued     16,576,088  
Common stock, price per share     $ 46  
Net proceeds from issuance     $ 823,000  
Underwriting discounts and commissions     38,800  
Stock issuance expenses     600  
2021 ATM Program | Common Stock        
Class Of Stock [Line Items]        
Net proceeds from issuance     $ 59,200  
Aggregate gross proceeds through equity issuance maximum potential amount   $ 250,000    
Issuance of common stock upon offering, net of offering costs, shares     1,294,050  
Proceeds from issuance of common stock gross     $ 60,800  
2024 ATM Program | Common Stock        
Class Of Stock [Line Items]        
Net proceeds from issuance     $ 59,500  
Aggregate gross proceeds through equity issuance maximum potential amount $ 500,000      
Issuance of common stock upon offering, net of offering costs, shares     1,147,893  
Proceeds from issuance of common stock gross     $ 60,400  
Pre Funded Warrants        
Class Of Stock [Line Items]        
Common stock, shares, issued     2,173,917  
Common stock, price per share     $ 45.9999