<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with the Workiva Platform-->
<!--Copyright 2026 Workiva-->
<!--r:019b0928-bdb7-7166-8fe3-25546f7c96df,g:c4940980-ee84-4bb2-99c5-809fb4ee051a-->
<xs:schema xmlns:xs="http://www.w3.org/2001/XMLSchema" xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:epam="http://www.epam.com/20251231" xmlns:xbrli="http://www.xbrl.org/2003/instance" xmlns:dtr-types="http://www.xbrl.org/dtr/type/2024-01-31" xmlns:xbrldt="http://xbrl.org/2005/xbrldt" attributeFormDefault="unqualified" elementFormDefault="qualified" targetNamespace="http://www.epam.com/20251231">
  <xs:import namespace="http://fasb.org/srt/2025" schemaLocation="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd"/>
  <xs:import namespace="http://fasb.org/us-gaap/2025" schemaLocation="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd"/>
  <xs:import namespace="http://www.xbrl.org/2003/instance" schemaLocation="http://www.xbrl.org/2003/xbrl-instance-2003-12-31.xsd"/>
  <xs:import namespace="http://www.xbrl.org/2003/linkbase" schemaLocation="http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd"/>
  <xs:import namespace="http://www.xbrl.org/dtr/type/2024-01-31" schemaLocation="https://www.xbrl.org/dtr/type/2024-01-31/types.xsd"/>
  <xs:import namespace="http://xbrl.org/2005/xbrldt" schemaLocation="http://www.xbrl.org/2005/xbrldt-2005.xsd"/>
  <xs:import namespace="http://xbrl.sec.gov/country/2025" schemaLocation="https://xbrl.sec.gov/country/2025/country-2025.xsd"/>
  <xs:import namespace="http://xbrl.sec.gov/cyd-af-sub/2025" schemaLocation="https://xbrl.sec.gov/cyd/2025/cyd-af-sub-2025.xsd"/>
  <xs:import namespace="http://xbrl.sec.gov/dei/2025" schemaLocation="https://xbrl.sec.gov/dei/2025/dei-2025.xsd"/>
  <xs:import namespace="http://xbrl.sec.gov/ecd/2025" schemaLocation="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd"/>
  <xs:annotation>
    <xs:appinfo>
      <link:linkbaseRef xmlns:xlink="http://www.w3.org/1999/xlink" xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" xlink:href="epam-20251231_pre.xml" xlink:role="http://www.xbrl.org/2003/role/presentationLinkbaseRef" xlink:type="simple"/>
      <link:linkbaseRef xmlns:xlink="http://www.w3.org/1999/xlink" xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" xlink:href="epam-20251231_def.xml" xlink:role="http://www.xbrl.org/2003/role/definitionLinkbaseRef" xlink:type="simple"/>
      <link:linkbaseRef xmlns:xlink="http://www.w3.org/1999/xlink" xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" xlink:href="epam-20251231_lab.xml" xlink:role="http://www.xbrl.org/2003/role/labelLinkbaseRef" xlink:type="simple"/>
      <link:linkbaseRef xmlns:xlink="http://www.w3.org/1999/xlink" xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" xlink:href="epam-20251231_cal.xml" xlink:role="http://www.xbrl.org/2003/role/calculationLinkbaseRef" xlink:type="simple"/>
      <link:roleType id="CoverPage" roleURI="http://www.epam.com/role/CoverPage">
        <link:definition>0000001 - Document - Cover Page</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="AuditInformation" roleURI="http://www.epam.com/role/AuditInformation">
        <link:definition>0000002 - Document - Audit Information</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="CONSOLIDATEDBALANCESHEETS" roleURI="http://www.epam.com/role/CONSOLIDATEDBALANCESHEETS">
        <link:definition>9952151 - Statement - CONSOLIDATED BALANCE SHEETS</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="CONSOLIDATEDBALANCESHEETSParenthetical" roleURI="http://www.epam.com/role/CONSOLIDATEDBALANCESHEETSParenthetical">
        <link:definition>9952152 - Statement - CONSOLIDATED BALANCE SHEETS (Parenthetical)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="CONSOLIDATEDSTATEMENTSOFINCOME" roleURI="http://www.epam.com/role/CONSOLIDATEDSTATEMENTSOFINCOME">
        <link:definition>9952153 - Statement - CONSOLIDATED STATEMENTS OF INCOME</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="CONSOLIDATEDSTATEMENTSOFCOMPREHENSIVEINCOME" roleURI="http://www.epam.com/role/CONSOLIDATEDSTATEMENTSOFCOMPREHENSIVEINCOME">
        <link:definition>9952154 - Statement - CONSOLIDATED STATEMENTS OF COMPREHENSIVE INCOME</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="CONSOLIDATEDSTATEMENTSOFCHANGESINEQUITY" roleURI="http://www.epam.com/role/CONSOLIDATEDSTATEMENTSOFCHANGESINEQUITY">
        <link:definition>9952155 - Statement - CONSOLIDATED STATEMENTS OF CHANGES IN EQUITY</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="CONSOLIDATEDSTATEMENTSOFCASHFLOWS" roleURI="http://www.epam.com/role/CONSOLIDATEDSTATEMENTSOFCASHFLOWS">
        <link:definition>9952156 - Statement - CONSOLIDATED STATEMENTS OF CASH FLOWS</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="CONSOLIDATEDSTATEMENTSOFCASHFLOWSParenthetical" roleURI="http://www.epam.com/role/CONSOLIDATEDSTATEMENTSOFCASHFLOWSParenthetical">
        <link:definition>9952157 - Statement - CONSOLIDATED STATEMENTS OF CASH FLOWS (Parenthetical)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="ORGANIZATIONANDSUMMARYOFSIGNIFICANTACCOUNTINGPOLICIES" roleURI="http://www.epam.com/role/ORGANIZATIONANDSUMMARYOFSIGNIFICANTACCOUNTINGPOLICIES">
        <link:definition>9952158 - Disclosure - ORGANIZATION AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="IMPACTOFTHEINVASIONOFUKRAINE" roleURI="http://www.epam.com/role/IMPACTOFTHEINVASIONOFUKRAINE">
        <link:definition>9952159 - Disclosure - IMPACT OF THE INVASION OF UKRAINE</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="ACQUISITIONS" roleURI="http://www.epam.com/role/ACQUISITIONS">
        <link:definition>9952160 - Disclosure - ACQUISITIONS</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="GOODWILLANDINTANGIBLEASSETSNET" roleURI="http://www.epam.com/role/GOODWILLANDINTANGIBLEASSETSNET">
        <link:definition>9952161 - Disclosure - GOODWILL AND INTANGIBLE ASSETS, NET</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="FAIRVALUEMEASUREMENTS" roleURI="http://www.epam.com/role/FAIRVALUEMEASUREMENTS">
        <link:definition>9952162 - Disclosure - FAIR VALUE MEASUREMENTS</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="DERIVATIVEFINANCIALINSTRUMENTS" roleURI="http://www.epam.com/role/DERIVATIVEFINANCIALINSTRUMENTS">
        <link:definition>9952163 - Disclosure - DERIVATIVE FINANCIAL INSTRUMENTS</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="PROPERTYANDEQUIPMENTNET" roleURI="http://www.epam.com/role/PROPERTYANDEQUIPMENTNET">
        <link:definition>9952164 - Disclosure - PROPERTY AND EQUIPMENT, NET</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="ACCRUEDEXPENSESANDOTHERCURRENTLIABILITIES" roleURI="http://www.epam.com/role/ACCRUEDEXPENSESANDOTHERCURRENTLIABILITIES">
        <link:definition>9952165 - Disclosure - ACCRUED EXPENSES AND OTHER CURRENT LIABILITIES</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="LEASES" roleURI="http://www.epam.com/role/LEASES">
        <link:definition>9952166 - Disclosure - LEASES</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="DEBT" roleURI="http://www.epam.com/role/DEBT">
        <link:definition>9952167 - Disclosure - DEBT</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="PENSIONANDPOSTRETIREMENTBENEFITS" roleURI="http://www.epam.com/role/PENSIONANDPOSTRETIREMENTBENEFITS">
        <link:definition>9952168 - Disclosure - PENSION AND POSTRETIREMENT BENEFITS</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="COSTOPTIMIZATIONPROGRAMS" roleURI="http://www.epam.com/role/COSTOPTIMIZATIONPROGRAMS">
        <link:definition>9952169 - Disclosure - COST OPTIMIZATION PROGRAMS</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="REVENUES" roleURI="http://www.epam.com/role/REVENUES">
        <link:definition>9952170 - Disclosure - REVENUES</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="POLANDRESEARCHANDDEVELOPMENTINCENTIVES" roleURI="http://www.epam.com/role/POLANDRESEARCHANDDEVELOPMENTINCENTIVES">
        <link:definition>9952171 - Disclosure - POLAND RESEARCH AND DEVELOPMENT INCENTIVES</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="STOCKHOLDERSEQUITY" roleURI="http://www.epam.com/role/STOCKHOLDERSEQUITY">
        <link:definition>9952172 - Disclosure - STOCKHOLDERS&#8217; EQUITY</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="INCOMETAXES" roleURI="http://www.epam.com/role/INCOMETAXES">
        <link:definition>9952173 - Disclosure - INCOME TAXES</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="EARNINGSPERSHARE" roleURI="http://www.epam.com/role/EARNINGSPERSHARE">
        <link:definition>9952174 - Disclosure - EARNINGS PER SHARE</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="COMMITMENTSANDCONTINGENCIES" roleURI="http://www.epam.com/role/COMMITMENTSANDCONTINGENCIES">
        <link:definition>9952175 - Disclosure - COMMITMENTS AND CONTINGENCIES</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="SEGMENTINFORMATION" roleURI="http://www.epam.com/role/SEGMENTINFORMATION">
        <link:definition>9952176 - Disclosure - SEGMENT INFORMATION</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="ACCUMULATEDOTHERCOMPREHENSIVEINCOMELOSS" roleURI="http://www.epam.com/role/ACCUMULATEDOTHERCOMPREHENSIVEINCOMELOSS">
        <link:definition>9952177 - Disclosure - ACCUMULATED OTHER COMPREHENSIVE INCOME (LOSS)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="VALUATIONANDQUALIFYINGACCOUNTS" roleURI="http://www.epam.com/role/VALUATIONANDQUALIFYINGACCOUNTS">
        <link:definition>9952178 - Disclosure - VALUATION AND QUALIFYING ACCOUNTS</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="ORGANIZATIONANDSUMMARYOFSIGNIFICANTACCOUNTINGPOLICIESPolicies" roleURI="http://www.epam.com/role/ORGANIZATIONANDSUMMARYOFSIGNIFICANTACCOUNTINGPOLICIESPolicies">
        <link:definition>9955511 - Disclosure - ORGANIZATION AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (Policies)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="ACQUISITIONSTables" roleURI="http://www.epam.com/role/ACQUISITIONSTables">
        <link:definition>9955512 - Disclosure - ACQUISITIONS (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="GOODWILLANDINTANGIBLEASSETSNETTables" roleURI="http://www.epam.com/role/GOODWILLANDINTANGIBLEASSETSNETTables">
        <link:definition>9955513 - Disclosure - GOODWILL AND INTANGIBLE ASSETS, NET (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="FAIRVALUEMEASUREMENTSTables" roleURI="http://www.epam.com/role/FAIRVALUEMEASUREMENTSTables">
        <link:definition>9955514 - Disclosure - FAIR VALUE MEASUREMENTS (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="DERIVATIVEFINANCIALINSTRUMENTSTables" roleURI="http://www.epam.com/role/DERIVATIVEFINANCIALINSTRUMENTSTables">
        <link:definition>9955515 - Disclosure - DERIVATIVE FINANCIAL INSTRUMENTS (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="PROPERTYANDEQUIPMENTNETTables" roleURI="http://www.epam.com/role/PROPERTYANDEQUIPMENTNETTables">
        <link:definition>9955516 - Disclosure - PROPERTY AND EQUIPMENT, NET (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="ACCRUEDEXPENSESANDOTHERCURRENTLIABILITIESTables" roleURI="http://www.epam.com/role/ACCRUEDEXPENSESANDOTHERCURRENTLIABILITIESTables">
        <link:definition>9955517 - Disclosure - ACCRUED EXPENSES AND OTHER CURRENT LIABILITIES (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="LEASESTables" roleURI="http://www.epam.com/role/LEASESTables">
        <link:definition>9955518 - Disclosure - LEASES (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="DEBTTables" roleURI="http://www.epam.com/role/DEBTTables">
        <link:definition>9955519 - Disclosure - DEBT (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="PENSIONANDPOSTRETIREMENTBENEFITSTables" roleURI="http://www.epam.com/role/PENSIONANDPOSTRETIREMENTBENEFITSTables">
        <link:definition>9955520 - Disclosure - PENSION AND POSTRETIREMENT BENEFITS (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="COSTOPTIMIZATIONPROGRAMSTables" roleURI="http://www.epam.com/role/COSTOPTIMIZATIONPROGRAMSTables">
        <link:definition>9955521 - Disclosure - COST OPTIMIZATION PROGRAMS (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="REVENUESTables" roleURI="http://www.epam.com/role/REVENUESTables">
        <link:definition>9955522 - Disclosure - REVENUES (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="STOCKHOLDERSEQUITYTables" roleURI="http://www.epam.com/role/STOCKHOLDERSEQUITYTables">
        <link:definition>9955523 - Disclosure - STOCKHOLDERS&#8217; EQUITY (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="INCOMETAXESTables" roleURI="http://www.epam.com/role/INCOMETAXESTables">
        <link:definition>9955524 - Disclosure - INCOME TAXES (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="EARNINGSPERSHARETables" roleURI="http://www.epam.com/role/EARNINGSPERSHARETables">
        <link:definition>9955525 - Disclosure - EARNINGS PER SHARE (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="SEGMENTINFORMATIONTables" roleURI="http://www.epam.com/role/SEGMENTINFORMATIONTables">
        <link:definition>9955526 - Disclosure - SEGMENT INFORMATION (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="ACCUMULATEDOTHERCOMPREHENSIVEINCOMELOSSTables" roleURI="http://www.epam.com/role/ACCUMULATEDOTHERCOMPREHENSIVEINCOMELOSSTables">
        <link:definition>9955527 - Disclosure - ACCUMULATED OTHER COMPREHENSIVE INCOME (LOSS) (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="ORGANIZATIONANDSUMMARYOFSIGNIFICANTACCOUNTINGPOLICIESPropertyandEquipmentDetails" roleURI="http://www.epam.com/role/ORGANIZATIONANDSUMMARYOFSIGNIFICANTACCOUNTINGPOLICIESPropertyandEquipmentDetails">
        <link:definition>9955528 - Disclosure - ORGANIZATION AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (Property and Equipment) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="ORGANIZATIONANDSUMMARYOFSIGNIFICANTACCOUNTINGPOLICIESGoodwillandOtherIndefiniteLivedIntangibleAssetsDetails" roleURI="http://www.epam.com/role/ORGANIZATIONANDSUMMARYOFSIGNIFICANTACCOUNTINGPOLICIESGoodwillandOtherIndefiniteLivedIntangibleAssetsDetails">
        <link:definition>9955529 - Disclosure - ORGANIZATION AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (Goodwill and Other Indefinite-Lived Intangible Assets) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="ORGANIZATIONANDSUMMARYOFSIGNIFICANTACCOUNTINGPOLICIESRisksandUncertaintiesDetails" roleURI="http://www.epam.com/role/ORGANIZATIONANDSUMMARYOFSIGNIFICANTACCOUNTINGPOLICIESRisksandUncertaintiesDetails">
        <link:definition>9955530 - Disclosure - ORGANIZATION AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (Risks and Uncertainties) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="IMPACTOFTHEINVASIONOFUKRAINEDetails" roleURI="http://www.epam.com/role/IMPACTOFTHEINVASIONOFUKRAINEDetails">
        <link:definition>9955531 - Disclosure - IMPACT OF THE INVASION OF UKRAINE (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="ACQUISITIONSNarrativeDetails" roleURI="http://www.epam.com/role/ACQUISITIONSNarrativeDetails">
        <link:definition>9955532 - Disclosure - ACQUISITIONS (Narrative) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="ACQUISITIONSScheduleofFairValuesofNetAssetsAcquiredandLiabilitiesAssumedDetails" roleURI="http://www.epam.com/role/ACQUISITIONSScheduleofFairValuesofNetAssetsAcquiredandLiabilitiesAssumedDetails">
        <link:definition>9955533 - Disclosure - ACQUISITIONS (Schedule of Fair Values of Net Assets Acquired and Liabilities Assumed) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="ACQUISITIONSScheduleofAcquiredFiniteLivedIntangibleAssetsbyMajorClassDetails" roleURI="http://www.epam.com/role/ACQUISITIONSScheduleofAcquiredFiniteLivedIntangibleAssetsbyMajorClassDetails">
        <link:definition>9955534 - Disclosure - ACQUISITIONS (Schedule of Acquired Finite-Lived Intangible Assets by Major Class) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="ACQUISITIONSConsolidatedProformaDetails" roleURI="http://www.epam.com/role/ACQUISITIONSConsolidatedProformaDetails">
        <link:definition>9955535 - Disclosure - ACQUISITIONS (Consolidated Pro forma) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="GOODWILLANDINTANGIBLEASSETSNETScheduleofGoodwillbyReportableSegmentDetails" roleURI="http://www.epam.com/role/GOODWILLANDINTANGIBLEASSETSNETScheduleofGoodwillbyReportableSegmentDetails">
        <link:definition>9955536 - Disclosure - GOODWILL AND INTANGIBLE ASSETS, NET (Schedule of Goodwill by Reportable Segment) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="GOODWILLANDINTANGIBLEASSETSNETGoodwillAccumulatedImpairmentLossesNarrativeDetails" roleURI="http://www.epam.com/role/GOODWILLANDINTANGIBLEASSETSNETGoodwillAccumulatedImpairmentLossesNarrativeDetails">
        <link:definition>9955537 - Disclosure - GOODWILL AND INTANGIBLE ASSETS, NET (Goodwill Accumulated Impairment Losses) (Narrative) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="GOODWILLANDINTANGIBLEASSETSNETScheduleofIntangibleAssetsComponentsandAmortizationExpenseRecognizedDetails" roleURI="http://www.epam.com/role/GOODWILLANDINTANGIBLEASSETSNETScheduleofIntangibleAssetsComponentsandAmortizationExpenseRecognizedDetails">
        <link:definition>9955538 - Disclosure - GOODWILL AND INTANGIBLE ASSETS, NET (Schedule of Intangible Assets Components and Amortization Expense Recognized) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="GOODWILLANDINTANGIBLEASSETSNETScheduleofEstimatedAmortizationExpenseDetails" roleURI="http://www.epam.com/role/GOODWILLANDINTANGIBLEASSETSNETScheduleofEstimatedAmortizationExpenseDetails">
        <link:definition>9955539 - Disclosure - GOODWILL AND INTANGIBLE ASSETS, NET (Schedule of Estimated Amortization Expense) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="FAIRVALUEMEASUREMENTSScheduleofFinancialAssetsandLiabilitiesMeasuredatFairValueonaRecurringBasisDetails" roleURI="http://www.epam.com/role/FAIRVALUEMEASUREMENTSScheduleofFinancialAssetsandLiabilitiesMeasuredatFairValueonaRecurringBasisDetails">
        <link:definition>9955540 - Disclosure - FAIR VALUE MEASUREMENTS (Schedule of Financial Assets and Liabilities Measured at Fair Value on a Recurring Basis) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="FAIRVALUEMEASUREMENTSNarrativeDetails" roleURI="http://www.epam.com/role/FAIRVALUEMEASUREMENTSNarrativeDetails">
        <link:definition>9955541 - Disclosure - FAIR VALUE MEASUREMENTS (Narrative) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="FAIRVALUEMEASUREMENTSScheduleofAcquisitionRelatedContingentConsiderationRollForwardDetails" roleURI="http://www.epam.com/role/FAIRVALUEMEASUREMENTSScheduleofAcquisitionRelatedContingentConsiderationRollForwardDetails">
        <link:definition>9955542 - Disclosure - FAIR VALUE MEASUREMENTS (Schedule of Acquisition-Related Contingent Consideration Roll Forward) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="FAIRVALUEMEASUREMENTSScheduleofEstimatedFairValuesofFinancialAssetsandLiabilitiesNotMeasuredatFairValueonaRecurringBasisDetails" roleURI="http://www.epam.com/role/FAIRVALUEMEASUREMENTSScheduleofEstimatedFairValuesofFinancialAssetsandLiabilitiesNotMeasuredatFairValueonaRecurringBasisDetails">
        <link:definition>9955543 - Disclosure - FAIR VALUE MEASUREMENTS (Schedule of Estimated Fair Values of Financial Assets and Liabilities Not Measured at Fair Value on a Recurring Basis) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="FAIRVALUEMEASUREMENTSNonMarketableSecuritiesWithoutReadilyDeterminableFairValuesNarrativeDetails" roleURI="http://www.epam.com/role/FAIRVALUEMEASUREMENTSNonMarketableSecuritiesWithoutReadilyDeterminableFairValuesNarrativeDetails">
        <link:definition>9955544 - Disclosure - FAIR VALUE MEASUREMENTS (Non-Marketable Securities Without Readily Determinable Fair Values) (Narrative) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="DERIVATIVEFINANCIALINSTRUMENTSDetails" roleURI="http://www.epam.com/role/DERIVATIVEFINANCIALINSTRUMENTSDetails">
        <link:definition>9955545 - Disclosure - DERIVATIVE FINANCIAL INSTRUMENTS (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="PROPERTYANDEQUIPMENTNETScheduleofComponentsofPropertyandEquipmentandDepreciationDetails" roleURI="http://www.epam.com/role/PROPERTYANDEQUIPMENTNETScheduleofComponentsofPropertyandEquipmentandDepreciationDetails">
        <link:definition>9955546 - Disclosure - PROPERTY AND EQUIPMENT, NET (Schedule of Components of Property and Equipment and Depreciation) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="PROPERTYANDEQUIPMENTNETNarrativeDetails" roleURI="http://www.epam.com/role/PROPERTYANDEQUIPMENTNETNarrativeDetails">
        <link:definition>9955547 - Disclosure - PROPERTY AND EQUIPMENT, NET (Narrative) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="ACCRUEDEXPENSESANDOTHERCURRENTLIABILITIESDetails" roleURI="http://www.epam.com/role/ACCRUEDEXPENSESANDOTHERCURRENTLIABILITIESDetails">
        <link:definition>9955548 - Disclosure - ACCRUED EXPENSES AND OTHER CURRENT LIABILITIES (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="LEASESNarrativeDetails" roleURI="http://www.epam.com/role/LEASESNarrativeDetails">
        <link:definition>9955549 - Disclosure - LEASES (Narrative) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="LEASESScheduleofComponentsofLeaseExpensesDetails" roleURI="http://www.epam.com/role/LEASESScheduleofComponentsofLeaseExpensesDetails">
        <link:definition>9955550 - Disclosure - LEASES (Schedule of Components of Lease Expenses) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="LEASESScheduleofSupplementalCashFlowInformationDetails" roleURI="http://www.epam.com/role/LEASESScheduleofSupplementalCashFlowInformationDetails">
        <link:definition>9955551 - Disclosure - LEASES (Schedule of Supplemental Cash Flow Information) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="LEASESScheduleofWeightedAverageRemainingLeaseTermandDiscountRateDetails" roleURI="http://www.epam.com/role/LEASESScheduleofWeightedAverageRemainingLeaseTermandDiscountRateDetails">
        <link:definition>9955552 - Disclosure - LEASES (Schedule of Weighted Average Remaining Lease Term and Discount Rate) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="LEASESScheduleofMaturityofOperatingLeaseLiabilitiesDetails" roleURI="http://www.epam.com/role/LEASESScheduleofMaturityofOperatingLeaseLiabilitiesDetails">
        <link:definition>9955553 - Disclosure - LEASES (Schedule of Maturity of Operating Lease Liabilities) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="LEASESScheduleofMaturityofOperatingLeaseLiabilitiesDetails_1" roleURI="http://www.epam.com/role/LEASESScheduleofMaturityofOperatingLeaseLiabilitiesDetails_1">
        <link:definition>9955553 - Disclosure - LEASES (Schedule of Maturity of Operating Lease Liabilities) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="DEBTNarrativeDetails" roleURI="http://www.epam.com/role/DEBTNarrativeDetails">
        <link:definition>9955554 - Disclosure - DEBT (Narrative) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="DEBTScheduleofOutstandingDebtAndBorrowingCapacityDetails" roleURI="http://www.epam.com/role/DEBTScheduleofOutstandingDebtAndBorrowingCapacityDetails">
        <link:definition>9955555 - Disclosure - DEBT (Schedule of Outstanding Debt And Borrowing Capacity) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="PENSIONANDPOSTRETIREMENTBENEFITSNarrativeDetails" roleURI="http://www.epam.com/role/PENSIONANDPOSTRETIREMENTBENEFITSNarrativeDetails">
        <link:definition>9955556 - Disclosure - PENSION AND POSTRETIREMENT BENEFITS (Narrative) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="PENSIONANDPOSTRETIREMENTBENEFITSScheduleofDefinedBenefitPlansDisclosuresDetails" roleURI="http://www.epam.com/role/PENSIONANDPOSTRETIREMENTBENEFITSScheduleofDefinedBenefitPlansDisclosuresDetails">
        <link:definition>9955557 - Disclosure - PENSION AND POSTRETIREMENT BENEFITS (Schedule of Defined Benefit Plans Disclosures) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="COSTOPTIMIZATIONPROGRAMSNarrativeDetails" roleURI="http://www.epam.com/role/COSTOPTIMIZATIONPROGRAMSNarrativeDetails">
        <link:definition>9955558 - Disclosure - COST OPTIMIZATION PROGRAMS (Narrative) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="COSTOPTIMIZATIONPROGRAMSActivityinRestructuringReservesDetails" roleURI="http://www.epam.com/role/COSTOPTIMIZATIONPROGRAMSActivityinRestructuringReservesDetails">
        <link:definition>9955559 - Disclosure - COST OPTIMIZATION PROGRAMS (Activity in Restructuring Reserves) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="REVENUESScheduleofDisaggregationofRevenuesDetails" roleURI="http://www.epam.com/role/REVENUESScheduleofDisaggregationofRevenuesDetails">
        <link:definition>9955560 - Disclosure - REVENUES (Schedule of Disaggregation of Revenues) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="REVENUESScheduleofTimingofRevenueRecognitionDetails" roleURI="http://www.epam.com/role/REVENUESScheduleofTimingofRevenueRecognitionDetails">
        <link:definition>9955561 - Disclosure - REVENUES (Schedule of Timing of Revenue Recognition) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="REVENUESScheduleofTimingofRevenueRecognitionDetails_1" roleURI="http://www.epam.com/role/REVENUESScheduleofTimingofRevenueRecognitionDetails_1">
        <link:definition>9955561 - Disclosure - REVENUES (Schedule of Timing of Revenue Recognition) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="REVENUESScheduleofContractAssetsandLiabilitiesDetails" roleURI="http://www.epam.com/role/REVENUESScheduleofContractAssetsandLiabilitiesDetails">
        <link:definition>9955562 - Disclosure - REVENUES (Schedule of Contract Assets and Liabilities) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="POLANDRESEARCHANDDEVELOPMENTINCENTIVESDetails" roleURI="http://www.epam.com/role/POLANDRESEARCHANDDEVELOPMENTINCENTIVESDetails">
        <link:definition>9955563 - Disclosure - POLAND RESEARCH AND DEVELOPMENT INCENTIVES (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="STOCKHOLDERSEQUITYScheduleofComponentsofStockBasedCompensationExpensesDetails" roleURI="http://www.epam.com/role/STOCKHOLDERSEQUITYScheduleofComponentsofStockBasedCompensationExpensesDetails">
        <link:definition>9955564 - Disclosure - STOCKHOLDERS&#8217; EQUITY (Schedule of Components of Stock-Based Compensation Expenses) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="STOCKHOLDERSEQUITYEquityPlansDetails" roleURI="http://www.epam.com/role/STOCKHOLDERSEQUITYEquityPlansDetails">
        <link:definition>9955565 - Disclosure - STOCKHOLDERS&#8217; EQUITY (Equity Plans) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="STOCKHOLDERSEQUITYScheduleofRestrictedStockandRestrictedStockUnitsActivityDetails" roleURI="http://www.epam.com/role/STOCKHOLDERSEQUITYScheduleofRestrictedStockandRestrictedStockUnitsActivityDetails">
        <link:definition>9955566 - Disclosure - STOCKHOLDERS&#8217; EQUITY (Schedule of Restricted Stock and Restricted Stock Units Activity) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="STOCKHOLDERSEQUITYScheduleofFairValueofRestrictedStockandRestrictedStockUnitsVestedDetails" roleURI="http://www.epam.com/role/STOCKHOLDERSEQUITYScheduleofFairValueofRestrictedStockandRestrictedStockUnitsVestedDetails">
        <link:definition>9955567 - Disclosure - STOCKHOLDERS&#8217; EQUITY (Schedule of Fair Value of Restricted Stock and Restricted Stock Units Vested) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="STOCKHOLDERSEQUITYRestrictedStockandRestrictedStockUnitsAdditionalInformationDetails" roleURI="http://www.epam.com/role/STOCKHOLDERSEQUITYRestrictedStockandRestrictedStockUnitsAdditionalInformationDetails">
        <link:definition>9955568 - Disclosure - STOCKHOLDERS&#8217; EQUITY (Restricted Stock and Restricted Stock Units Additional Information) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="STOCKHOLDERSEQUITYScheduleofStockOptionActivityDetails" roleURI="http://www.epam.com/role/STOCKHOLDERSEQUITYScheduleofStockOptionActivityDetails">
        <link:definition>9955569 - Disclosure - STOCKHOLDERS&#8217; EQUITY (Schedule of Stock Option Activity) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="STOCKHOLDERSEQUITYScheduleofBlackScholesValuationModelAssumptionsDetails" roleURI="http://www.epam.com/role/STOCKHOLDERSEQUITYScheduleofBlackScholesValuationModelAssumptionsDetails">
        <link:definition>9955570 - Disclosure - STOCKHOLDERS&#8217; EQUITY (Schedule of Black Scholes Valuation Model Assumptions) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="STOCKHOLDERSEQUITYStockOptionsAdditionalInformationDetails" roleURI="http://www.epam.com/role/STOCKHOLDERSEQUITYStockOptionsAdditionalInformationDetails">
        <link:definition>9955571 - Disclosure - STOCKHOLDERS&#8217; EQUITY (Stock Options Additional Information) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="STOCKHOLDERSEQUITYEmployeeStockPurchasePlanAdditionalInformationDetails" roleURI="http://www.epam.com/role/STOCKHOLDERSEQUITYEmployeeStockPurchasePlanAdditionalInformationDetails">
        <link:definition>9955572 - Disclosure - STOCKHOLDERS&#8217; EQUITY (Employee Stock Purchase Plan Additional Information) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="STOCKHOLDERSEQUITYShareRepurchasesAdditionalInformationDetails" roleURI="http://www.epam.com/role/STOCKHOLDERSEQUITYShareRepurchasesAdditionalInformationDetails">
        <link:definition>9955573 - Disclosure - STOCKHOLDERS&#8217; EQUITY (Share Repurchases Additional Information) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="INCOMETAXESScheduleofIncomeBeforeProvisionforIncomeTaxesDetails" roleURI="http://www.epam.com/role/INCOMETAXESScheduleofIncomeBeforeProvisionforIncomeTaxesDetails">
        <link:definition>9955574 - Disclosure - INCOME TAXES (Schedule of Income Before Provision for Income Taxes) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="INCOMETAXESScheduleofProvisionforIncomeTaxesDetails" roleURI="http://www.epam.com/role/INCOMETAXESScheduleofProvisionforIncomeTaxesDetails">
        <link:definition>9955575 - Disclosure - INCOME TAXES (Schedule of Provision for Income Taxes) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="INCOMETAXESNarrativeDetails" roleURI="http://www.epam.com/role/INCOMETAXESNarrativeDetails">
        <link:definition>9955576 - Disclosure - INCOME TAXES (Narrative) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="INCOMETAXESEffectiveTaxRateReconciliationDetails" roleURI="http://www.epam.com/role/INCOMETAXESEffectiveTaxRateReconciliationDetails">
        <link:definition>9955577 - Disclosure - INCOME TAXES (Effective Tax Rate Reconciliation) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="INCOMETAXESDeferredIncomeTaxesDetails" roleURI="http://www.epam.com/role/INCOMETAXESDeferredIncomeTaxesDetails">
        <link:definition>9955578 - Disclosure - INCOME TAXES (Deferred Income Taxes) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="INCOMETAXESScheduleofUnrecognizedTaxBenefitsDetails" roleURI="http://www.epam.com/role/INCOMETAXESScheduleofUnrecognizedTaxBenefitsDetails">
        <link:definition>9955579 - Disclosure - INCOME TAXES (Schedule of Unrecognized Tax Benefits) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="INCOMETAXESCashIncomeTaxesPaidNetofRefundsDetails" roleURI="http://www.epam.com/role/INCOMETAXESCashIncomeTaxesPaidNetofRefundsDetails">
        <link:definition>9955580 - Disclosure - INCOME TAXES (Cash Income Taxes Paid, Net of Refunds) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="EARNINGSPERSHAREDetails" roleURI="http://www.epam.com/role/EARNINGSPERSHAREDetails">
        <link:definition>9955581 - Disclosure - EARNINGS PER SHARE (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="COMMITMENTSANDCONTINGENCIESDetails" roleURI="http://www.epam.com/role/COMMITMENTSANDCONTINGENCIESDetails">
        <link:definition>9955582 - Disclosure - COMMITMENTS AND CONTINGENCIES (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="SEGMENTINFORMATIONReconciliationofSegmentOperatingProfittoConsolidatedIncomeBeforeProvisionforIncomeTaxesDetails" roleURI="http://www.epam.com/role/SEGMENTINFORMATIONReconciliationofSegmentOperatingProfittoConsolidatedIncomeBeforeProvisionforIncomeTaxesDetails">
        <link:definition>9955583 - Disclosure - SEGMENT INFORMATION (Reconciliation of Segment Operating Profit to Consolidated Income Before Provision for Income Taxes (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="SEGMENTINFORMATIONPhysicalLocationsandValuesofLongLivedAssetsDetails" roleURI="http://www.epam.com/role/SEGMENTINFORMATIONPhysicalLocationsandValuesofLongLivedAssetsDetails">
        <link:definition>9955584 - Disclosure - SEGMENT INFORMATION (Physical Locations and Values of Long-Lived Assets) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="SEGMENTINFORMATIONRevenuesbyCustomerLocationDetails" roleURI="http://www.epam.com/role/SEGMENTINFORMATIONRevenuesbyCustomerLocationDetails">
        <link:definition>9955585 - Disclosure - SEGMENT INFORMATION (Revenues by Customer Location) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="ACCUMULATEDOTHERCOMPREHENSIVEINCOMELOSSDetails" roleURI="http://www.epam.com/role/ACCUMULATEDOTHERCOMPREHENSIVEINCOMELOSSDetails">
        <link:definition>9955586 - Disclosure - ACCUMULATED OTHER COMPREHENSIVE INCOME (LOSS) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="VALUATIONANDQUALIFYINGACCOUNTSDetails" roleURI="http://www.epam.com/role/VALUATIONANDQUALIFYINGACCOUNTSDetails">
        <link:definition>9955587 - Disclosure - VALUATION AND QUALIFYING ACCOUNTS (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
    </xs:appinfo>
  </xs:annotation>
  <xs:element id="epam_AuditorInformationAbstract" abstract="true" name="AuditorInformationAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="epam_TradeReceivablesAndContractAssetsAfterAllowanceForCreditLossCurrent" abstract="false" name="TradeReceivablesAndContractAssetsAfterAllowanceForCreditLossCurrent" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="epam_TradeReceivablesAndContractAssetsAllowanceForCreditLossCurrent" abstract="false" name="TradeReceivablesAndContractAssetsAllowanceForCreditLossCurrent" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="epam_WeightedAverageNumberBasicAndDilutedSharesOutstandingAbstract" abstract="true" name="WeightedAverageNumberBasicAndDilutedSharesOutstandingAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="epam_IncreaseDecreaseInTradeReceivablesAndContractAssets" abstract="false" name="IncreaseDecreaseInTradeReceivablesAndContractAssets" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="epam_IncreaseDecreaseInOperatingLeaseLiabilities" abstract="false" name="IncreaseDecreaseInOperatingLeaseLiabilities" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="epam_CashPaidDuringtheYearAbstract" abstract="true" name="CashPaidDuringtheYearAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="epam_RisksAndUncertaintiesPolicyPolicyTextBlock" abstract="false" name="RisksAndUncertaintiesPolicyPolicyTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="epam_ScheduleOfWeightedAverageRemainingLeaseTermsAndDiscountRatesTableTextBlock" abstract="false" name="ScheduleOfWeightedAverageRemainingLeaseTermsAndDiscountRatesTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="epam_ShareBasedCompensationRestrictedStockAndRestrictedStockUnitsVestedFairValueTableTextBlock" abstract="false" name="ShareBasedCompensationRestrictedStockAndRestrictedStockUnitsVestedFairValueTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="epam_HumanitarianCommitmentMember" abstract="true" name="HumanitarianCommitmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="epam_UnusualOrInfrequentItemsOrBothStandbyResourcesExpense" abstract="false" name="UnusualOrInfrequentItemsOrBothStandbyResourcesExpense" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="epam_A2025AcquisitionsMember" abstract="true" name="A2025AcquisitionsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="epam_FirstDerivativeLtdMember" abstract="true" name="FirstDerivativeLtdMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="epam_NEORISMember" abstract="true" name="NEORISMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="epam_A2024AcquisitionsMember" abstract="true" name="A2024AcquisitionsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="epam_A2023AcquisitionsMember" abstract="true" name="A2023AcquisitionsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="epam_BusinessCombinationNumberOfProfessionals" abstract="false" name="BusinessCombinationNumberOfProfessionals" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="epam_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedPropertyPlantAndEquipmentAndOtherNoncurrentAssets" abstract="false" name="BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedPropertyPlantAndEquipmentAndOtherNoncurrentAssets" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="epam_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssetsAcquiredIncludingGoodwill" abstract="false" name="BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssetsAcquiredIncludingGoodwill" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="epam_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNoncontrollingInterest" abstract="false" name="BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNoncontrollingInterest" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="epam_AmericasSegmentMember" abstract="true" name="AmericasSegmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="epam_EuropeSegmentMember" abstract="true" name="EuropeSegmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="epam_FirstDerivativeAcquisitionMember" abstract="true" name="FirstDerivativeAcquisitionMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="epam_Other2024AcquisitionsMember" abstract="true" name="Other2024AcquisitionsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="epam_SoftwareLicensesMember" abstract="true" name="SoftwareLicensesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="epam_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityForeignCurrencyTranslationAdjustment" abstract="false" name="FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityForeignCurrencyTranslationAdjustment" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="epam_CreditFacility2025Member" abstract="true" name="CreditFacility2025Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="epam_CreditFacility2021Member" abstract="true" name="CreditFacility2021Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="epam_BuildingAndLandImprovementsMember" abstract="true" name="BuildingAndLandImprovementsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="epam_MinskBelarusMember" abstract="true" name="MinskBelarusMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="epam_AssetAcquisitionContingentConsiderationMeasurementInput" abstract="false" name="AssetAcquisitionContingentConsiderationMeasurementInput" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:pureItemType"/>
  <xs:element id="epam_AssetAcquisitionProvisionalInformationInitialAccountingIncompleteIntangibleAssets" abstract="false" name="AssetAcquisitionProvisionalInformationInitialAccountingIncompleteIntangibleAssets" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="epam_AssetAcquisitionContingentConsiderationLiabilityPeriodIncreaseDecrease" abstract="false" name="AssetAcquisitionContingentConsiderationLiabilityPeriodIncreaseDecrease" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="epam_LeaseCostTable" abstract="true" name="LeaseCostTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="epam_LeaseCostLineItems" abstract="true" name="LeaseCostLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="epam_RightofUseAssetsObtainedinExchangeForLeaseObligationsAbstract" abstract="true" name="RightofUseAssetsObtainedinExchangeForLeaseObligationsAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="epam_NonCashChangesDuetoLeaseModificationsAbstract" abstract="true" name="NonCashChangesDuetoLeaseModificationsAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="epam_OperatingLeaseRightOfUseAssetModification" abstract="false" name="OperatingLeaseRightOfUseAssetModification" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="epam_OperatingLeaseLiabilityModification" abstract="false" name="OperatingLeaseLiabilityModification" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="epam_WeightedAverageRemainingLeaseTermAbstract" abstract="true" name="WeightedAverageRemainingLeaseTermAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="epam_WeightedAverageDiscountRateAbstract" abstract="true" name="WeightedAverageDiscountRateAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="epam_A2025CreditAgreementMember" abstract="true" name="A2025CreditAgreementMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="epam_A2025CreditAgreementPortionDenominatedInOtherCurrenciesMember" abstract="true" name="A2025CreditAgreementPortionDenominatedInOtherCurrenciesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="epam_A2021CreditAgreementMember" abstract="true" name="A2021CreditAgreementMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="epam_LineOfCreditFacilityAccordionFeatureIncreaseLimit" abstract="false" name="LineOfCreditFacilityAccordionFeatureIncreaseLimit" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="epam_EmployeeRelatedLiabilitiesCurrentMember" abstract="true" name="EmployeeRelatedLiabilitiesCurrentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="epam_A2025CostOptimizationProgramMember" abstract="true" name="A2025CostOptimizationProgramMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="epam_A2023CostOptimizationProgramMember" abstract="true" name="A2023CostOptimizationProgramMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="epam_A2024CostOptimizationProgramMember" abstract="true" name="A2024CostOptimizationProgramMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="epam_NumberOfGeographicMarkets" abstract="false" name="NumberOfGeographicMarkets" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="epam_CentralAndEasternEuropeMember" abstract="true" name="CentralAndEasternEuropeMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="epam_RussiaSegmentMember" abstract="true" name="RussiaSegmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="epam_ConsumerGoodsRetailAndTravelMember" abstract="true" name="ConsumerGoodsRetailAndTravelMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="epam_SoftwareAndHiTechSectorMember" abstract="true" name="SoftwareAndHiTechSectorMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="epam_BusinessInformationAndMediaSectorsMember" abstract="true" name="BusinessInformationAndMediaSectorsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="epam_OtherSectorsMember" abstract="true" name="OtherSectorsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="epam_LicensingMember" abstract="true" name="LicensingMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="epam_A2023ResearchAndDevelopmentActivitiesMember" abstract="true" name="A2023ResearchAndDevelopmentActivitiesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="epam_A2024ResearchAndDevelopmentActivitiesMember" abstract="true" name="A2024ResearchAndDevelopmentActivitiesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="epam_CompanyPersonnelMember" abstract="true" name="CompanyPersonnelMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="epam_NonEmployeeDirectorsMember" abstract="true" name="NonEmployeeDirectorsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="epam_ShareBasedCompensationArrangementByShareBasedPaymentAwardMaximumSalaryContributionPercent" abstract="false" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardMaximumSalaryContributionPercent" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="epam_ShareBasedCompensationArrangementByShareBasedPaymentAwardStockPlanOfferingPeriod" abstract="false" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardStockPlanOfferingPeriod" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="epam_AwardMetricAxis" abstract="true" name="AwardMetricAxis" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:dimensionItem" type="xbrli:stringItemType"/>
  <xs:element id="epam_AwardMetricDomain" abstract="true" name="AwardMetricDomain" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="epam_ServicePeriodMember" abstract="true" name="ServicePeriodMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="epam_PerformanceTargetsMember" abstract="true" name="PerformanceTargetsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="epam_AwardSettlementTypeAxis" abstract="true" name="AwardSettlementTypeAxis" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:dimensionItem" type="xbrli:stringItemType"/>
  <xs:element id="epam_AwardSettlementTypeDomain" abstract="true" name="AwardSettlementTypeDomain" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="epam_EquitySettledAwardMember" abstract="true" name="EquitySettledAwardMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="epam_CashSettledAwardMember" abstract="true" name="CashSettledAwardMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="epam_AwardClassificationAxis" abstract="true" name="AwardClassificationAxis" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:dimensionItem" type="xbrli:stringItemType"/>
  <xs:element id="epam_AwardClassificationDomain" abstract="true" name="AwardClassificationDomain" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="epam_EquityClassifiedAwardMember" abstract="true" name="EquityClassifiedAwardMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="epam_LiabilityClassifiedAwardMember" abstract="true" name="LiabilityClassifiedAwardMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="epam_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsModifiedInPeriod" abstract="false" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsModifiedInPeriod" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="epam_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsModifiedInPeriodWeightedAverageModificationDateFairValue" abstract="false" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsModifiedInPeriodWeightedAverageModificationDateFairValue" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:perShareItemType"/>
  <xs:element id="epam_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNotConsideredGrantedInPeriod" abstract="false" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNotConsideredGrantedInPeriod" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="epam_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAggregateIntrinsicValueRollForward" abstract="true" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAggregateIntrinsicValueRollForward" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="epam_A2025ShareRepurchaseProgramMember" abstract="true" name="A2025ShareRepurchaseProgramMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="epam_A2024ShareRepurchaseProgramMember" abstract="true" name="A2024ShareRepurchaseProgramMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="epam_A2023ShareRepurchaseProgramMember" abstract="true" name="A2023ShareRepurchaseProgramMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="epam_ScheduleofChangeinTaxLegislationTable" abstract="true" name="ScheduleofChangeinTaxLegislationTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="epam_LegalActNameAxis" abstract="true" name="LegalActNameAxis" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:dimensionItem" type="xbrli:stringItemType"/>
  <xs:element id="epam_LegalActNameDomain" abstract="true" name="LegalActNameDomain" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="epam_TaxCutsAndJobsActMember" abstract="true" name="TaxCutsAndJobsActMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="epam_ScheduleofChangeinTaxLegislationLineItems" abstract="true" name="ScheduleofChangeinTaxLegislationLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="epam_U.S.TaxRateOnForeignCashAndCertainOtherNetCurrentAssets" abstract="false" name="U.S.TaxRateOnForeignCashAndCertainOtherNetCurrentAssets" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="epam_U.S.TaxRateOnForeignEarnings" abstract="false" name="U.S.TaxRateOnForeignEarnings" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="epam_EffectiveIncomeTaxRateReconciliationForeignDisregardedEntitiesAmount" abstract="false" name="EffectiveIncomeTaxRateReconciliationForeignDisregardedEntitiesAmount" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="epam_EffectiveIncomeTaxRateReconciliationGILTIAndBEATUSTaxesAmount" abstract="false" name="EffectiveIncomeTaxRateReconciliationGILTIAndBEATUSTaxesAmount" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="epam_EffectiveIncomeTaxRateReconciliationForeignDisregardedEntitiesPercent" abstract="false" name="EffectiveIncomeTaxRateReconciliationForeignDisregardedEntitiesPercent" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="epam_DeferredTaxAssetsAccruedSalesDiscounts" abstract="false" name="DeferredTaxAssetsAccruedSalesDiscounts" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="epam_DeferredTaxAssetsDeferredRevenue" abstract="false" name="DeferredTaxAssetsDeferredRevenue" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="epam_DeferredTaxAssetsOperatingLeaseLiability" abstract="false" name="DeferredTaxAssetsOperatingLeaseLiability" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="epam_DeferredTaxAssetUnrealizedCurrencyLossAndOtherComprehensiveLoss" abstract="false" name="DeferredTaxAssetUnrealizedCurrencyLossAndOtherComprehensiveLoss" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="epam_DeferredTaxLiabilitiesResearchAndDevelopmentCreditCarryforward" abstract="false" name="DeferredTaxLiabilitiesResearchAndDevelopmentCreditCarryforward" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="epam_DeferredTaxLiabilitiesForeignCurrencyExchange" abstract="false" name="DeferredTaxLiabilitiesForeignCurrencyExchange" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="epam_DeferredTaxLiabilitiesDisregardedForeignSubsidiaries" abstract="false" name="DeferredTaxLiabilitiesDisregardedForeignSubsidiaries" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="epam_CloudServicesMember" abstract="true" name="CloudServicesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="epam_LongTermPurchaseCommitmentPercentage" abstract="false" name="LongTermPurchaseCommitmentPercentage" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="epam_NumberOfReportableSegmentsNotDisclosedFlag" abstract="false" name="NumberOfReportableSegmentsNotDisclosedFlag" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="epam_SegmentOperatingProfitLoss" abstract="false" name="SegmentOperatingProfitLoss" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="epam_OtherCountriesMember" abstract="true" name="OtherCountriesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="epam_ReclassificationFromAOCICurrentPeriodBeforeTaxForeignCurrencyAttributableToParent" abstract="false" name="ReclassificationFromAOCICurrentPeriodBeforeTaxForeignCurrencyAttributableToParent" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
</xs:schema>
