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Certain Balance Sheet Items - Prepaid expenses and other assets (Details) - USD ($) $ in Thousands | Dec. 31, 2022 | Dec. 31, 2021
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Prepaid Expense and Other Assets, Current [Abstract] |  |
Prepaid manufacturing expenses | $ 51,694 | $ 47,991
Other prepaid expenses | 4,647 | 3,809
Other assets | 14,984 | 2,096
Total prepaid expense and other assets | 71,325 | 53,896
Less long-term portion | (26,301) | (13,414)
Total prepaid expense and other assets, current | $ 45,024 | $ 40,482

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