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Summary of Significant Accounting Policies - Concentrations of Credit Risk (Details) - USD ($) | 12 Months Ended
--- | ---
Dec. 31, 2022 | Dec. 31, 2021 | Dec. 31, 2020
Concentration Risk [Line Items] |  |  |
Accounts receivable, allowance for credit loss | $ 0 | $ 0 |
Total revenues | 660,116,000 | 443,310,000 | $ 267,594,000
Geographic Concentration Risk |  |  |
Concentration Risk [Line Items] |  |  |
Total revenues | 660,116,000 | 443,310,000 | 267,594,000
United States | Geographic Concentration Risk |  |  |
Concentration Risk [Line Items] |  |  |
Total revenues | 437,989,000 | 293,089,000 | 106,918,000
Switzerland | Geographic Concentration Risk |  |  |
Concentration Risk [Line Items] |  |  |
Total revenues | 166,836,000 | 134,117,000 | 95,949,000
Ireland | Geographic Concentration Risk |  |  |
Concentration Risk [Line Items] |  |  |
Total revenues | 3,000 | 14,000 | 30,552,000
Belgium | Geographic Concentration Risk |  |  |
Concentration Risk [Line Items] |  |  |
Total revenues | 2,088,000 | 199,000 | 20,086,000
Japan | Geographic Concentration Risk |  |  |
Concentration Risk [Line Items] |  |  |
Total revenues | 47,939,000 | 11,934,000 | 10,644,000
All other foreign | Geographic Concentration Risk |  |  |
Concentration Risk [Line Items] |  |  |
Total revenues | $ 5,261,000 | $ 3,957,000 | $ 3,445,000
Roche and Baxalta | Accounts Receivable | Customer Concentration Risk |  |  |
Concentration Risk [Line Items] |  |  |
Concentration Risk, Percentage (instant date) | 52.00% | 90.00% |
Partner A | Sales | Customer Concentration Risk |  |  |
Concentration Risk [Line Items] |  |  |
Concentration risk, percentage | 20.00% | 25.00% | 35.00%
Partner B | Sales | Customer Concentration Risk |  |  |
Concentration Risk [Line Items] |  |  |
Concentration risk, percentage | 46.00% | 48.00% | 26.00%
Partner C | Sales | Customer Concentration Risk |  |  |
Concentration Risk [Line Items] |  |  |
Concentration risk, percentage | 0.00% | 0.00% | 11.00%
Partner D | Sales | Customer Concentration Risk |  |  |
Concentration Risk [Line Items] |  |  |
Concentration risk, percentage | 0.00% | 10.00% | 0.00%

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- Definition Amount of allowance for credit loss on accounts receivable, classified as current. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02(4) -URI http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 310 -SubTopic 10 -Section 50 -Paragraph 4 -URI http://asc.fasb.org/extlink&oid=123577603&loc=d3e5074-111524 Reference 3: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 326 -SubTopic 20 -Section 45 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=124255206&loc=SL82895884-210446 + Details
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