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Revenue - Disaggregation of Revenue (Details) - USD ($) $ in Thousands | 12 Months Ended
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Dec. 31, 2022 | Dec. 31, 2021 | Dec. 31, 2020
Disaggregation of Revenue [Line Items] |  |  |
Total revenues | $ 660,116 | $ 443,310 | $ 267,594
Royalties |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Total revenues | 360,475 | 203,900 | 88,596
Product sales, net |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Total revenues | 191,030 | 104,224 | 55,987
Sales of bulk rHuPH20 |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Total revenues | 82,084 | 80,960 | 38,956
Sale of proprietary products |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Total revenues | 72,849 | 23,264 | 17,031
Sale of Device Partnered Products |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Total revenues | 36,097 | 0 | 0
Revenues under collaborative agreements |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Total revenues | 108,611 | 135,186 | 123,011
Upfront license and target nomination fees |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Total revenues | 30,000 | 42,000 | 37,264
Event-based development milestones and regulatory milestone and other fees |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Total revenues | 59,000 | 42,000 | 69,500
Sales-based milestones |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Total revenues | 10,000 | 50,000 | 15,000
Device Licensing and development revenue |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Total revenues | $ 9,611 | $ 1,186 | $ 1,247

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- Definition Amount, excluding tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer. Tax collected from customer is tax assessed by governmental authority that is both imposed on and concurrent with specific revenue-producing transaction, including, but not limited to, sales, use, value added and excise. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 30 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=123359005&loc=d3e8906-108599 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 40 -URI http://asc.fasb.org/extlink&oid=123359005&loc=d3e9031-108599 Reference 3: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 41 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=123359005&loc=d3e9038-108599 Reference 4: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 32 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=123359005&loc=d3e8933-108599 Reference 5: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 32 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=123359005&loc=d3e8933-108599 Reference 6: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 606 -SubTopic 10 -Section 50 -Paragraph 4 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=123351226&loc=SL49130543-203045 Reference 7: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 22 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=123359005&loc=d3e8736-108599 Reference 8: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 22 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=123359005&loc=d3e8736-108599 Reference 9: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 42 -URI http://asc.fasb.org/extlink&oid=123359005&loc=d3e9054-108599 Reference 10: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 606 -SubTopic 10 -Section 50 -Paragraph 5 -URI http://asc.fasb.org/extlink&oid=123351226&loc=SL49130545-203045 Reference 11: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 924 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SAB Topic 11.L) -URI http://asc.fasb.org/extlink&oid=6472922&loc=d3e499488-122856 + Details
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