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Certain Balance Sheet Items | 12 Months Ended
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Dec. 31, 2022
Balance Sheet Related Disclosures [Abstract] |
Certain Balance Sheet Items | Certain Balance Sheet Items Accounts receivable consisted of the following (in thousands):
|  | December 31, 2022 |  | December 31, 2021
Accounts receivable from product sales to partners |  | $ | 62,979 |  |  | $ | 18,504 |
Accounts receivable from revenues under collaborative agreements |  | 18,776 |  |  | 5,422 |
Accounts receivable from royalty payments |  | 100,900 |  |  | 63,555 |
Accounts receivable from other product sales |  | 6,229 |  |  | 4,634 |
Contract assets |  | 44,102 |  |  | — |
Subtotal |  | $ | 232,986 |  |  | $ | 92,115 |
Allowance for distribution fees and discounts |  | (1,914) |  |  | (1,140) |
Total accounts receivable |  | $ | 231,072 |  |  | $ | 90,975 |
Inventories consisted of the following (in thousands):
|  | December 31, 2022 |  | December 31, 2021
Raw materials |  | $ | 13,792 |  |  | $ | 10,672 |
Work-in-process |  | 40,361 |  |  | 17,451 |
Finished goods |  | 45,970 |  |  | 25,785 |
Total inventories |  | $ | 100,123 |  |  | $ | 53,908 |
Prepaid expenses and other assets consisted of the following (in thousands):
|  | December 31, 2022 |  | December 31, 2021
Prepaid manufacturing expenses |  | $ | 51,694 |  |  | $ | 47,991 |
Other prepaid expenses |  | 4,647 |  |  | 3,809 |
Other assets |  | 14,984 |  |  | 2,096 |
Total prepaid expenses and other assets |  | $ | 71,325 |  |  | $ | 53,896 |
Less long-term portion |  | (26,301) |  |  | (13,414) |
Total prepaid expenses and other assets, current |  | $ | 45,024 |  |  | $ | 40,482 |
Prepaid manufacturing expenses include raw materials, slot reservation fees and other amounts paid to contract manufacturing organizations. Such amounts are reclassified to work-in-process inventory as materials are used or the contract manufacturing organization services are complete. Property and equipment, net consisted of the following (in thousands):
|  | December 31, 2022 |  | December 31, 2021
Research equipment |  | $ | 7,380 |  |  | $ | 7,174 |
Manufacturing equipment |  | 27,893 |  |  | 5,719 |
Computer and office equipment |  | 7,855 |  |  | 5,370 |
Leasehold improvements |  | 6,729 |  |  | 1,628 |
Subtotal |  | $ | 49,857 |  |  | $ | 19,891 |
Accumulated depreciation and amortization |  | (14,756) |  |  | (13,100) |
Subtotal |  | $ | 35,101 |  |  | $ | 6,791 |
Right of use of assets |  | 40,469 |  |  | 2,003 |
Property and equipment, net |  | $ | 75,570 |  |  | $ | 8,794 |
Depreciation and amortization expense was approximately $6.5 million, $3.0 million, and $3.3 million, inclusive of ROU asset amortization of $3.0 million, $1.6 million and $1.7 million for the years ended December 31, 2022, 2021 and 2020, respectively. Accrued expenses consisted of the following (in thousands):
|  | December 31, 2022 |  | December 31, 2021
Accrued compensation and payroll taxes |  | $ | 19,939 |  |  | $ | 9,858 |
Accrued outsourced manufacturing expenses |  | 12,190 |  |  | 6,514 |
Income taxes payable |  | — |  |  | 1,439 |
Product returns and sales allowance |  | 30,261 |  |  | 706 |
Other accrued expenses |  | 29,771 |  |  | 3,648 |
Lease liability |  | 34,788 |  |  | 2,820 |
Total accrued expenses |  | $ | 126,949 |  |  | $ | 24,985 |
Less long-term portion |  | (30,433) |  |  | (544) |
Total accrued expenses, current |  | $ | 96,516 |  |  | $ | 24,441 |
Expense associated with the accretion of the lease liabilities was approximately $0.5 million, $0.3 million and $0.5 million for the twelve months ended December 31, 2022, 2021 and 2020, respectively. Total lease expense for the twelve months ended December 31, 2022, 2021 and 2020 was $3.3 million, $1.9 million and $2.2 million, respectively. Cash paid for amounts related to leases for the twelve months ended December 31, 2022, 2021 and 2020 was $4.2 million, $2.7 million and $3.2 million, respectively.

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- Definition The entire disclosure for supplemental balance sheet disclosures, including descriptions and amounts for assets, liabilities, and equity. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -URI http://asc.fasb.org/topic&trid=2122208 + Details
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