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Revenue - Textuals (Details) - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2022 | Dec. 31, 2021 | Dec. 31, 2020
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |
Revenue related to licenses granted to collaboration partners | $ 429,500 |  |
Recognition of deferred revenue | (2,494) | $ (1,496) | $ (4,119)
Deferred revenues | 5,499 | 4,276 |
Deferred Credits and Other Liabilities | 5,500 |  |
Contract assets | 44,102 | $ 0 |
License fees and event-based payments |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |
Recognition of deferred revenue | 2,000 |  |
Product sales, net |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |
Deferred Credits and Other Liabilities, Current | 75,200 |  |
2017 Roche |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |
Development milestones | 59,000 |  |
OtherCollaborators |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |
Deferred revenues | $ 80,700 |  |

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