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Summary of Significant Accounting Policies - Concentrations of Credit Risk (Details) - USD ($)	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Concentration Risk [Line Items]
Accounts receivable, allowance for credit loss	$ 0	$ 0
Total revenues	660,116,000	443,310,000	$ 267,594,000
Geographic Concentration Risk
Concentration Risk [Line Items]
Total revenues	660,116,000	443,310,000	267,594,000
United States | Geographic Concentration Risk
Concentration Risk [Line Items]
Total revenues	437,989,000	293,089,000	106,918,000
Switzerland | Geographic Concentration Risk
Concentration Risk [Line Items]
Total revenues	166,836,000	134,117,000	95,949,000
Ireland | Geographic Concentration Risk
Concentration Risk [Line Items]
Total revenues	3,000	14,000	30,552,000
Belgium | Geographic Concentration Risk
Concentration Risk [Line Items]
Total revenues	2,088,000	199,000	20,086,000
Japan | Geographic Concentration Risk
Concentration Risk [Line Items]
Total revenues	47,939,000	11,934,000	10,644,000
All other foreign | Geographic Concentration Risk
Concentration Risk [Line Items]
Total revenues	$ 5,261,000	$ 3,957,000	$ 3,445,000
Roche and Baxalta | Accounts Receivable | Customer Concentration Risk
Concentration Risk [Line Items]
Concentration Risk, Percentage (instant date)	52.00%	90.00%
Partner A | Sales | Customer Concentration Risk
Concentration Risk [Line Items]
Concentration risk, percentage	20.00%	25.00%	35.00%
Partner B | Sales | Customer Concentration Risk
Concentration Risk [Line Items]
Concentration risk, percentage	46.00%	48.00%	26.00%
Partner C | Sales | Customer Concentration Risk
Concentration Risk [Line Items]
Concentration risk, percentage	0.00%	0.00%	11.00%
Partner D | Sales | Customer Concentration Risk
Concentration Risk [Line Items]
Concentration risk, percentage	0.00%	10.00%	0.00%

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