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Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Operating activities:      
Net income $ 202,129 $ 402,710 $ 129,085
Adjustments to reconcile net income to net cash provided by operating activities:      
Share-based compensation 24,397 20,820 17,204
Depreciation and amortization 6,493 2,997 3,284
Amortization of intangible assets 43,148 0 0
Total amortization of debt discount 7,839 3,642 14,136
Amortization of (accretion of discounts) premiums on marketable securities 1,106 2,257 839
Realized loss on marketable securities 1,727 0 0
Loss (gain) on disposal of equipment 129 0 (772)
Deferral of unearned revenue 0 0 4,632
Recognition of deferred revenue (2,494) (1,496) (4,119)
Lease payments deferred (903) (751) (1,033)
Loss on impairment of right-of-use asset 0 0 577
Induced conversion expense related to convertible notes 2,712 20,960 0
Deferred income taxes (including benefit from valuation allowance release) 40,005 (155,434) 0
Other (227) (3) (13)
Changes in operating assets and liabilities:      
Accounts receivable, net (83,941) 6,755 (38,288)
Inventories (17,481) 7,371 (31,388)
Prepaid expenses and other assets (9,064) (11,555) 2,518
Accounts payable and accrued expenses 24,535 1,167 (41,208)
Net cash provided by operating activities 240,110 299,440 55,454
Investing activities:      
Purchases of marketable securities (255,208) (652,515) (226,185)
Proceeds from maturities of marketable securities 746,127 247,683 305,967
Acquisitions of business, net of cash acquired 999,120 0 0
Purchases of property and equipment (4,810) (1,457) (2,504)
Proceeds from sale of assets 26,006 0 1,076
Net cash (used in) provided by investing activities (487,005) (406,289) 78,354
Financing activities:      
Proceeds from term loan 250,000 0 0
Repayment of term loan (250,000) 0 0
Proceeds from revolving credit facilities 120,000 0 0
Repayment of revolving credit facilities 120,000 0 0
Proceeds from issuance of 2027 Convertible Notes, net 0 784,875 0
Repayments of convertible debt 77,453 369,064 19,560
Proceeds from issuance of 2028 Convertible Notes 702,000 0 0
Purchase of capped call (69,120) 0 0
Payment of debt issuance cost (7,104) (424) 0
Repurchase of common stock (200,002) (350,058) (150,117)
Proceeds from issuance of common stock under equity incentive plans, net of taxes paid related to net share settlement 14,050 12,536 63,393
Net cash provided by (used in) financing activities 362,371 77,865 (106,284)
Net increase (decrease) in cash, cash equivalents and restricted cash 115,476 (28,984) 27,524
Cash, cash equivalents and restricted cash at beginning of period 119,219 148,203 120,679
Cash, cash equivalents and restricted cash at end of period 234,695 119,219 148,203
Supplemental disclosure of cash flow information:      
Interest paid 6,107 3,296 6,534
Income taxes paid (received), net 16,224 (375) 180
Supplemental disclosure of non-cash investing and financing activities:      
Amounts accrued for purchases of property and equipment 6,229 72 117
Right-of-use assets obtained in exchange for lease obligation 34,435 318 1,746
Common stock issued for induced conversion related to convertible notes $ 1,018 $ 7,865 $ 0