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Consolidated Statements of Income - USD ($)
shares in Thousands, $ in Thousands
 12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Revenues      
Total revenues $ 829,253 $ 660,116 $ 443,310
Operating expenses      
Cost of sales 192,361 139,304 81,413
Amortization of intangible assets 73,773 43,148 0
Research and development 76,363 66,607 35,672
Selling, general and administrative 149,182 143,526 50,323
Total operating expenses 491,679 392,585 167,408
Operating income 337,574 267,531 275,902
Other income (expense)      
Investment and other income, net 16,317 1,046 1,102
Induced conversion expense related to convertible notes 0 (2,712) (20,960)
Contingent liability fair value measurement gain 13,200 0 0
Interest expense (18,762) (16,947) (7,526)
Net income before income taxes 348,329 248,918 248,518
Income tax expense (benefit) 66,735 46,789 (154,192)
Net income $ 281,594 $ 202,129 $ 402,710
Earnings per share      
Basic (usd per share) $ 2.13 $ 1.48 $ 2.86
Diluted (usd per share) $ 2.10 $ 1.44 $ 2.74
Weighted average common shares outstanding      
Basic (in shares) 131,927 136,844 140,646
Diluted (shares) 134,197 140,608 146,796
Royalties      
Revenues      
Total revenues $ 447,865 $ 360,475 $ 203,900
Product sales, net      
Revenues      
Total revenues 300,854 191,030 104,224
Revenues under collaborative agreements      
Revenues      
Total revenues $ 80,534 $ 108,611 $ 135,186