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Summary of Significant Accounting Policies - Concentrations of Credit Risk (Details) | 12 Months Ended
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Dec. 31, 2024 USD ($) bank financialInstitution | Dec. 31, 2023 USD ($) | Dec. 31, 2022 USD ($)
Concentration Risk [Line Items] |  |  |
Commercial banks where cash and cash equivalents are maintained | bank | 2 |  |
Financial institutions where marketable securities are maintained | financialInstitution | 1 |  |
Accounts receivable, allowance for credit loss | $ 0 | $ 0 |
Total revenues | 1,015,324,000 | 829,253,000 | $ 660,116,000
Geographic Concentration Risk |  |  |
Concentration Risk [Line Items] |  |  |
Total revenues | 1,015,324,000 | 829,253,000 | 660,116,000
United States | Geographic Concentration Risk |  |  |
Concentration Risk [Line Items] |  |  |
Total revenues | 690,461,000 | 587,196,000 | 437,989,000
Switzerland | Geographic Concentration Risk |  |  |
Concentration Risk [Line Items] |  |  |
Total revenues | 212,391,000 | 149,024,000 | 166,836,000
Belgium | Geographic Concentration Risk |  |  |
Concentration Risk [Line Items] |  |  |
Total revenues | 84,005,000 | 58,354,000 | 2,088,000
Japan | Geographic Concentration Risk |  |  |
Concentration Risk [Line Items] |  |  |
Total revenues | 18,939,000 | 15,096,000 | 47,939,000
All other foreign | Geographic Concentration Risk |  |  |
Concentration Risk [Line Items] |  |  |
Total revenues | $ 9,528,000 | $ 19,583,000 | $ 5,264,000
Janssen and Roche | Accounts Receivable | Customer Concentration Risk |  |  |
Concentration Risk [Line Items] |  |  |
Concentration risk, percentage (instant date) | 60.00% |  |
Janssen, Roche and Teva | Accounts Receivable | Customer Concentration Risk |  |  |
Concentration Risk [Line Items] |  |  |
Concentration risk, percentage (instant date) |  | 69.00% |
Partner A | Sales | Customer Concentration Risk |  |  |
Concentration Risk [Line Items] |  |  |
Concentration risk, percentage | 41.00% | 44.00% | 46.00%
Partner B | Sales | Customer Concentration Risk |  |  |
Concentration Risk [Line Items] |  |  |
Concentration risk, percentage | 17.00% | 19.00% | 20.00%
Partner C | Sales | Customer Concentration Risk |  |  |
Concentration Risk [Line Items] |  |  |
Concentration risk, percentage | 8.00% | 10.00% | 0.00%

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