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Revenue - Disaggregation of Revenue (Details) - USD ($) $ in Thousands | 12 Months Ended
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Dec. 31, 2024 | Dec. 31, 2023 | Dec. 31, 2022
Disaggregation of Revenue [Line Items] |  |  |
Total revenues | $ 1,015,324 | $ 829,253 | $ 660,116
Royalties |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Total revenues | 570,991 | 447,865 | 360,475
Product sales, net |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Total revenues | 303,492 | 300,854 | 191,030
Proprietary product sales |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Total revenues | 166,620 | 130,834 | 72,849
Bulk rHuPH20 sales |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Total revenues | 86,334 | 115,442 | 82,084
Device partnered product sales |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Total revenues | 50,538 | 54,578 | 36,097
Revenues under collaborative agreements |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Total revenues | 140,841 | 80,534 | 108,611
Upfront license and target nomination fees |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Total revenues | 27,000 | 2,000 | 30,000
Event-based development and regulatory milestones and other fees |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Total revenues | 72,500 | 69,000 | 59,000
Sales-based milestones |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Total revenues | 30,000 | 0 | 10,000
Device licensing and development revenue |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Total revenues | $ 11,341 | $ 9,534 | $ 9,611

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