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Stockholders' Equity - Share-based Compensation Expense (Details) - USD ($) $ in Thousands | 3 Months Ended | 9 Months Ended
--- | --- | ---
Sep. 30, 2025 | Sep. 30, 2024 | Sep. 30, 2025 | Sep. 30, 2024
Share-based Payment Arrangement, Expensed and Capitalized, Amount [Line Items] |  |  |  |
Total share-based compensation expense | $ 12,160 | $ 12,578 | $ 34,994 | $ 31,923
Stock options |  |  |  |
Share-based Payment Arrangement, Expensed and Capitalized, Amount [Line Items] |  |  |  |
Total share-based compensation expense | 3,734 | 3,922 | 11,316 | 12,115
RSUs, PSUs and ESPP |  |  |  |
Share-based Payment Arrangement, Expensed and Capitalized, Amount [Line Items] |  |  |  |
Total share-based compensation expense | 8,426 | 8,656 | 23,678 | 19,808
Research and development |  |  |  |
Share-based Payment Arrangement, Expensed and Capitalized, Amount [Line Items] |  |  |  |
Total share-based compensation expense | 3,601 | 3,598 | 10,375 | 9,511
Selling, general and administrative |  |  |  |
Share-based Payment Arrangement, Expensed and Capitalized, Amount [Line Items] |  |  |  |
Total share-based compensation expense | $ 8,559 | $ 8,980 | $ 24,619 | $ 22,412

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