<SEC-DOCUMENT>0002090209-25-000004.txt : 20251006
<SEC-HEADER>0002090209-25-000004.hdr.sgml : 20251006
<ACCEPTANCE-DATETIME>20251006171423
ACCESSION NUMBER:		0002090209-25-000004
CONFORMED SUBMISSION TYPE:	3
PUBLIC DOCUMENT COUNT:		2
CONFORMED PERIOD OF REPORT:	20251001
FILED AS OF DATE:		20251006
DATE AS OF CHANGE:		20251006

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Caudill Cortney
		CENTRAL INDEX KEY:			0002090209
		ORGANIZATION NAME:           	

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-32335
		FILM NUMBER:		251377617

	MAIL ADDRESS:	
		STREET 1:		C/O HALOZYME THERAPEUTICS, INC.
		STREET 2:		12390 EL CAMINO REAL
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92130

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			HALOZYME THERAPEUTICS, INC.
		CENTRAL INDEX KEY:			0001159036
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		ORGANIZATION NAME:           	03 Life Sciences
		EIN:				880488686
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		12390 EL CAMINO REAL
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92130
		BUSINESS PHONE:		(858) 794-8889

	MAIL ADDRESS:	
		STREET 1:		12390 EL CAMINO REAL
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92130

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	HALOZYME THERAPEUTICS INC
		DATE OF NAME CHANGE:	20040312

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	GLOBAL YACHT SERVICES INC
		DATE OF NAME CHANGE:	20010912
</SEC-HEADER>
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<TYPE>3
<SEQUENCE>1
<FILENAME>form3-10062025_091019.xml
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    <periodOfReport>2025-10-01</periodOfReport>

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    <issuer>
        <issuerCik>0001159036</issuerCik>
        <issuerName>HALOZYME THERAPEUTICS, INC.</issuerName>
        <issuerTradingSymbol>HALO</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0002090209</rptOwnerCik>
            <rptOwnerName>Caudill Cortney</rptOwnerName>
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            <rptOwnerStreet1>C/O HALOZYME THERAPEUTICS, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>12390 EL CAMINO REAL</rptOwnerStreet2>
            <rptOwnerCity>SAN DIEGO</rptOwnerCity>
            <rptOwnerState>CA</rptOwnerState>
            <rptOwnerZipCode>92130</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
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            <isDirector>false</isDirector>
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            <isTenPercentOwner>false</isTenPercentOwner>
            <isOther>false</isOther>
            <officerTitle>SVP, CHIEF OPERATING OFFICER</officerTitle>
            <otherText></otherText>
        </reportingOwnerRelationship>
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        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
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                <sharesOwnedFollowingTransaction>
                    <value>7674</value>
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    <derivativeTable>
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            <securityTitle>
                <value>Option to Purchase Common Stock</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>33.51</value>
            </conversionOrExercisePrice>
            <exerciseDate>
                <value>2024-11-01</value>
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            <securityTitle>
                <value>Option to Purchase Common Stock</value>
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            <exerciseDate>
                <value>2026-02-20</value>
                <footnoteId id="F1"/>
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            <expirationDate>
                <value>2035-02-20</value>
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                <value>Restricted Stock Unit</value>
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            <exerciseDate>
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            <securityTitle>
                <value>Performance Stock Unit</value>
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            <conversionOrExercisePrice>
                <value>0</value>
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            <exerciseDate>
                <value>2027-02-23</value>
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                <underlyingSecurityTitle>
                    <value>Common Stock</value>
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        <derivativeHolding>
            <securityTitle>
                <value>Performance Stock Unit</value>
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            <exerciseDate>
                <value>2027-02-23</value>
                <footnoteId id="F3"/>
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            <expirationDate>
                <footnoteId id="F3"/>
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            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
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                    <value>9246</value>
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                    <value>D</value>
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                    <value></value>
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        </derivativeHolding>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">This option vests one-fourth on such date and then vests 1/48th monthly thereafter.</footnote>
        <footnote id="F2">One-fourth of the original grant vests on such date and one-fourth vests annually thereafter. Represents a restricted stock unit award with no exercise price.</footnote>
        <footnote id="F3">Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock. The Issuer awarded the reporting person performance-based vesting stock units (&quot;PSUs&quot;) on February 23, 2024 that included a performance measurement period ending December 31, 2024. This PSU holding represents the Issuer's determination of the number of stock units that became eligible to vest based on performance for such performance period. The stock units remain subject to a service-based requirement through the third anniversary of the PSU grant date.</footnote>
    </footnotes>

    <remarks>Exhibit List: Exhibit 24 - Power of Attorney</remarks>

    <ownerSignature>
        <signatureName>/s/ James R. Oehler, Attorney-in-Fact</signatureName>
        <signatureDate>2025-10-06</signatureDate>
    </ownerSignature>
</ownershipDocument>
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</DOCUMENT>
<DOCUMENT>
<TYPE>EX-24
<SEQUENCE>2
<FILENAME>ex24-10062025_091019.htm
<TEXT>
<!DOCTYPE html PUBLIC "-//IETF//DTD HTML//EN">
<html><head><title>ex24-10062025_091019.htm</title><meta name="author" content="Barbara Birer"><meta name="date" content="09/30/2025"></head><body style="margin-top:0;font-family:Times New Roman; font-size:10pt; color:#000000">
<p style="margin:0px"><br></p>
<p style="margin:0px"><br></p>
<p style="margin:0px; font-size:12pt" align="right"><b>EXHIBIT 24</b></p>
<p style="margin:0px" align="right"><br></p>
<p style="margin:0px; font-size:12pt" align="center"><b>LIMITED POWER OF ATTORNEY</b></p>
<p style="margin:0px; font-size:12pt" align="center"><b>FOR </b></p>
<p style="margin:0px; font-size:12pt" align="center"><b>HALOZYME THERAPEUTICS, INC.</b></p>
<p style="margin:0px"><br></p>
<p style="margin:0px; text-indent:48px; font-size:12pt">Know all by these presents, that the undersigned hereby constitutes and appoints each of James R. Oehler, Nicole LaBrosse and Jennifer Benoit, signing singly, the undersigned's true and lawful attorneys-in-fact to:</p>
<p style="margin:0px"><br></p>
<p style="margin-top:0px; margin-bottom:-2px; text-indent:48px; width:96px; font-size:12pt; float:left">(1)</p>
<p style="margin:0px; padding-left:96px; text-indent:-2px; font-size:12pt">execute for and on behalf of the undersigned, in the undersigned&#146;s capacity as an officer, director and/or stockholder of Halozyme Therapeutics, Inc. (the &#147;<u>Company</u>&#148;), Forms ID,&nbsp;3, 4, and 5 and amendments thereto in accordance with Section&nbsp;16(a) of the Securities Exchange Act of 1934, as amended (the &#147;<u>Exchange Act</u>&#148;), and the rules thereunder; </p>
<p style="margin:0px; clear:left"><br></p>
<p style="margin-top:0px; margin-bottom:-2px; text-indent:48px; width:96px; font-size:12pt; float:left">(2)</p>
<p style="margin:0px; padding-left:96px; text-indent:-2px; font-size:12pt">do and perform any and all acts for and on behalf of the undersigned which may be necessary or desirable to complete and execute any such Form ID,&nbsp;3, 4, or 5 or amendment thereto and timely file such form with the United States Securities and Exchange Commission (the &#147;<u>SEC</u>&#148;) and any stock exchange or similar authority; </p>
<p style="margin:0px; clear:left"><br></p>
<p style="margin-top:0px; margin-bottom:-2px; text-indent:48px; width:96px; font-size:12pt; float:left">(3)</p>
<p style="margin:0px; padding-left:96px; text-indent:-2px; font-size:12pt">take such actions as may be necessary or appropriate to enable the undersigned to submit and file forms, schedules and other documents with the SEC utilizing the SEC&#146;s Electronic Data Gathering and Retrieval (&#147;<u>EDGAR</u>&#148;) system, which actions may include (a) enrolling the undersigned in EDGAR Next and (b) preparing, executing and submitting to the SEC a Form ID, amendments thereto, and such other documents and information as may be necessary or appropriate to obtain codes and passwords enabling the undersigned to make filings and submissions utilizing the EDGAR system;</p>
<p style="margin:0px; clear:left"><br></p>
<p style="margin-top:0px; margin-bottom:-2px; text-indent:48px; width:96px; font-size:12pt; float:left">(4)</p>
<p style="margin:0px; padding-left:96px; text-indent:-2px; font-size:12pt">act as an account administrator for the undersigned&#146;s EDGAR account, including: (a)&nbsp;appointing, removing and replacing account administrators, account users, technical administrators and delegated entities; (b) maintaining the security of the undersigned&#146;s EDGAR account, including modification of access codes; (c) maintaining, modifying and certifying the accuracy of information on the undersigned&#146;s EDGAR account dashboard; (d) acting as the EDGAR point of contact with respect to the undersigned&#146;s EDGAR account; and (e) any other actions contemplated by Rule 10 of Regulation S-T with respect to account administrators;</p>
<p style="margin:0px; clear:left"><br></p>
<p style="margin-top:0px; margin-bottom:-2px; text-indent:48px; width:96px; font-size:12pt; float:left">(5)</p>
<p style="margin:0px; padding-left:96px; text-indent:-2px; font-size:12pt">cause the Company to accept a delegation of authority from any of the undersigned&#146;s EDGAR account administrators and, pursuant to that delegation, authorize the Company&#146;s EDGAR account administrators to appoint, remove or replace users for the undersigned&#146;s EDGAR account; and</p>
<p style="margin:0px; clear:left"><br></p>
<p style="margin-top:0px; margin-bottom:-2px; text-indent:48px; width:96px; font-size:12pt; float:left">(6)</p>
<p style="margin:0px; padding-left:96px; text-indent:-2px; font-size:12pt">take any other action of any type whatsoever which, in the opinion of such attorney-in-fact, may be necessary or desirable in connection with the foregoing authority, it being understood that the documents executed by such attorney-in-fact on behalf of the undersigned pursuant to this Power of Attorney shall be in such form and shall contain such terms and conditions as such attorney-in-fact may approve.</p>
<p style="margin:0px; clear:left"><br></p>
<p style="margin:0px; text-indent:48px; font-size:12pt">The undersigned hereby grants to each such attorney-in-fact full power and authority to do and perform any and every act and thing whatsoever requisite, necessary, or proper to be done in the exercise of any of the rights and powers herein granted, as fully to all intents and purposes as the undersigned might or could do if personally present, with full power of substitution or revocation, hereby ratifying and confirming all that such attorneys-in-fact, or such attorneys-in-fact's substitute or substitutes, shall lawfully do or cause to be done by virtue of this Limited Power of Attorney and the rights and powers herein granted. &nbsp;</p>
<p style="margin:0px"><br></p>
<p style="margin:0px; text-indent:48px; font-size:12pt">The undersigned acknowledges that: (i) this Limited Power of Attorney does not relieve the undersigned from responsibility for compliance with the undersigned&#146;s obligations under Section 16 of the Exchange Act, including, without, limitation, the reporting requirements under Section 16(a) of the Exchange Act and the foregoing attorneys-in-fact, in serving in such capacity at the request of the undersigned, are not assuming, nor is the Company assuming, any of the undersigned's responsibilities to comply with Section&nbsp;16 of the Exchange Act; (ii) this Limited Power of Attorney authorizes, but does not require, the attorneys-in-fact to act at his or her discretion on information provided to such attorneys-in-fact without independent verification of such information; (iii) any documents prepared and/or executed by the attorneys-in-fact on behalf of the undersigned pursuant to this Limited Power of Attorney will be in such form and will contain such information as the attorneys-in-fact, in his or her discretion, deems necessary or desirable; and (iv) neither the Company nor the attorneys-in-fact assumes any liability for the undersigned&#146;s responsibility to comply with the requirements of Section 16 of the Exchange Act, any liability of the undersigned for any failure to comply with such requirements, or any liability of the undersigned for disgorgement of profits under Section 16(b) of the Exchange Act.</p>
<p style="margin:0px"><br></p>
<p style="margin:0px; text-indent:48px; font-size:12pt">This Limited Power of Attorney shall remain in full force and effect until the undersigned is no longer required to file Forms ID,&nbsp;3, 4, and 5 with respect to the undersigned's holdings of and transactions in securities of the Company, unless earlier revoked by the undersigned in a signed writing delivered to the foregoing attorneys-in-fact. &nbsp;This Limited Power of Attorney may be filed with the SEC as a confirming statement of the authority granted herein.</p>
<p style="margin:0px"><br></p>
<p style="margin:0px"><br></p>
<p style="margin:0px; text-indent:48px; font-size:12pt">IN WITNESS WHEREOF, the undersigned has caused this Power of Attorney to be executed as of this 1st day of October, 2025.</p>
<p style="margin:0px"><br></p>
<p style="margin:0px"><br></p>
<p style="margin:0px"><br></p>
<p style="margin-top:0px; margin-bottom:-2px; text-indent:288px; width:422.4px; font-size:12pt; float:left">Signature: &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</p>
<p style="margin:0px; text-indent:-2px; font-size:12pt"><u>/s/ Cortney Caudill</u></p>
<p style="margin:0px; clear:left"><br></p>
<p style="margin:0px"><br></p>
<p style="margin:0px; text-indent:288px; font-size:12pt">Print Name: &nbsp;&nbsp;<u>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Cortney Caudill</u></p>
<p style="margin:0px"><br></p>
<p style="margin:0px"><br></p>
<p style="margin:0px"><br></p>
<p style="margin:0px" align="center">1</p>
<p style="margin:0px"><br></p>
<p style="margin:0px"><br></p>
</body></html>
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</SEC-DOCUMENT>
