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Condensed Consolidated Balance Sheet and Statement of Operations and Comprehensive Loss Components | 6 Months Ended
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Jun. 30, 2025
Organization, Consolidation and Presentation of Financial Statements [Abstract] |
Condensed Consolidated Balance Sheet and Statement of Operations and Comprehensive Loss Components | Condensed Consolidated Balance Sheet and Statement of Operations and Comprehensive Loss Components Prepaid Expenses and Other Current Assets Prepaid expenses and other current assets consist of the following:
| As of June 30, 2025 |  | As of December 31, 2024
| (amounts in thousands)
Prepaid expenses | $ | 16,575 |  |  | $ | 13,562 |
Other current assets | 2,549 |  |  | 6,708 |
Total prepaid expenses and other current assets | $ | 19,124 |  |  | $ | 20,270 |
Property and Equipment, Net Property and equipment, net consist of the following:
| As of June 30, 2025 |  | As of December 31, 2024
| (amounts in thousands)
Computer equipment and software | $ | 74,791 |  |  | $ | 73,312 |
Capitalized software | 26,312 |  |  | 25,921 |
Laboratory equipment | 108,576 |  |  | 103,795 |
Furniture and fixtures | 9,129 |  |  | 9,110 |
Leasehold improvements/Leased buildings | 63,295 |  |  | 63,039 |
Aircraft and leased equipment | 21,249 |  |  | 21,249 |
Total property and equipment | 303,352 |  |  | 296,426 |
Less: accumulated depreciation and amortization | (242,037) |  |  | (228,609) |
Property and equipment, net | $ | 61,315 |  |  | $ | 67,817 |
Total depreciation and amortization expense was $6.4 million and $11.6 million for the three months ended June 30, 2025 and 2024, respectively, and $13.5 million and $29.3 million for the six months ended June 30, 2025 and 2024, respectively. Accrued Expenses and Other Current Liabilities Accrued expenses and other current liabilities consist of the following:
| As of June 30, 2025 |  | As of December 31, 2024
| (amounts in thousands)
Trade accruals | $ | 5,749 |  |  | $ | 7,131 |
Accrued payroll and employee medical | 18,308 |  |  | 17,882 |
Accrued bonus | 13,516 |  |  | 25,736 |
Current portion of early exercise stock option liability | 327 |  |  | 4,957 |
Contract liability | 5,340 |  |  | 7,470 |
Current portion of operating lease liabilities | 7,291 |  |  | 6,080 |
Other accrued expenses | 10,826 |  |  | 8,286 |
Total accrued expenses and other current liabilities | $ | 61,357 |  |  | $ | 77,542 |
Other Long-Term Liabilities Other long-term liabilities consist of the following:
| As of June 30, 2025 |  | As of December 31, 2024
| (amounts in thousands)
Long-term operating lease liabilities, net of current portion | $ | 37,983 |  |  | $ | 38,651 |
Long-term portion of early exercise stock option liability | 380 |  |  | 5,767 |
Total other long-term liabilities | $ | 38,363 |  |  | $ | 44,418 |
Other Expense, Net Other expense, net, consists of the following:
| Three Months Ended June 30, |  | Six Months Ended June 30,
| 2025 |  | 2024 |  | 2025 |  | 2024
| (amounts in thousands)
Loss on debt extinguishment | $ | (17,930) |  |  | $ | — |  |  | $ | (17,930) |  |  | $ | — |
Other | (411) |  |  | (141) |  |  | (428) |  |  | (360) |
Total other expense, net | $ | (18,341) |  |  | $ | (141) |  |  | $ | (18,358) |  |  | $ | (360) |

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