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Income Taxes - Narrative (Details) - USD ($) | 12 Months Ended |
--- | --- | ---
Dec. 31, 2018 | Dec. 31, 2017 | Dec. 31, 2016 | Dec. 31, 2015
Operating Loss Carryforwards [Line Items] |  |  |  |
Federal income tax rates | 21.00% | 34.00% | 34.00% |
Operating loss carryforwards, expiring in future | $ 307,400,000 |  |  |
Operating loss carryforwards, carryforward indefinitely | 616,200,000 |  |  |
Unrecognized tax benefits | 59,800,000 | $ 25,600,000 | $ 15,700,000 | $ 7,900,000
Unrecognized tax benefits that would impact effective tax rate | 4,500,000 |  |  |
Unrecognized tax benefits that would impact effective tax rate, adjustment to deferred tax assets and valuation allowance | 55,300,000 |  |  |
Penalties and interest accrued | 1,300,000 |  |  |
Penalties and interest expense | 700,000 | 200,000 | $ 400,000 |
Undistributed earnings of foreign subsidiaries | 0 |  |  |
Estimated reduction in deferred tax assets due to remeasurement |  | 63,100,000 |  |
Estimated tax benefit from repealed corporate AMT |  | 1,400,000 |  |
Estimated transition tax inclusion |  | $ 0 |  |
Domestic |  |  |  |
Operating Loss Carryforwards [Line Items] |  |  |  |
Operating loss carryforwards | 923,600,000 |  |  |
Domestic | Research Tax Credit Carryforward |  |  |  |
Operating Loss Carryforwards [Line Items] |  |  |  |
Tax credit carryforward, amount | 145,000,000 |  |  |
Tax credit carryforward, valuation allowance | 36,100,000 |  |  |
State |  |  |  |
Operating Loss Carryforwards [Line Items] |  |  |  |
Operating loss carryforwards | 403,500,000 |  |  |
State | Research Tax Credit Carryforward |  |  |  |
Operating Loss Carryforwards [Line Items] |  |  |  |
Tax credit carryforward, amount | 76,800,000 |  |  |
Tax credit carryforward, valuation allowance | 19,100,000 |  |  |
State | State Enterprise Tax Credit Carryforward |  |  |  |
Operating Loss Carryforwards [Line Items] |  |  |  |
Tax credit carryforward, amount | 3,700,000 |  |  |
Foreign |  |  |  |
Operating Loss Carryforwards [Line Items] |  |  |  |
Operating loss carryforwards | 288,000,000 |  |  |
Operating loss carryforwards, carryforward indefinitely | 265,100,000 |  |  |
Operating loss carryforwards, acquired | $ 22,900,000 |  |  |

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