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Cash, Cash Equivalents and Short-Term Investments - Schedule of Components (Details) - USD ($)
$ in Millions
Mar. 31, 2022
Dec. 31, 2021
Cash and Cash Equivalents [Line Items]    
Cash and cash equivalents, at carrying value $ 445.5 $ 533.0
Cash equivalents 445.5 533.0
Short-term investments, amortized cost 1,083.1 1,193.8
Short-term investments, unrealized gain 0.0 0.5
Short-term investments, unrealized loss (33.0) (9.2)
Short-term investments, estimated fair value 1,050.1 1,185.1
Total cash, cash equivalents, and short term investments, before unrealized gains (losses) on investments 1,528.6 1,726.8
Total cash, cash equivalents, and short term investments 1,495.6 1,718.1
Corporate notes and obligations    
Cash and Cash Equivalents [Line Items]    
Short-term investments, amortized cost 531.7 607.4
Short-term investments, unrealized gain 0.0 0.4
Short-term investments, unrealized loss (15.6) (4.0)
Short-term investments, estimated fair value 516.1 603.8
U.S. Treasury securities    
Cash and Cash Equivalents [Line Items]    
Short-term investments, amortized cost 264.6 240.4
Short-term investments, unrealized gain 0.0 0.0
Short-term investments, unrealized loss (9.2) (2.9)
Short-term investments, estimated fair value 255.4 237.5
Asset backed securities    
Cash and Cash Equivalents [Line Items]    
Short-term investments, amortized cost 138.7 140.7
Short-term investments, unrealized gain 0.0 0.1
Short-term investments, unrealized loss (4.4) (1.2)
Short-term investments, estimated fair value 134.3 139.6
Municipal securities    
Cash and Cash Equivalents [Line Items]    
Short-term investments, amortized cost 68.7 70.5
Short-term investments, unrealized gain 0.0 0.0
Short-term investments, unrealized loss (2.8) (0.7)
Short-term investments, estimated fair value 65.9 69.8
Commercial paper    
Cash and Cash Equivalents [Line Items]    
Short-term investments, amortized cost 24.4 61.7
Short-term investments, unrealized gain 0.0 0.0
Short-term investments, unrealized loss 0.0 0.0
Short-term investments, estimated fair value 24.4 61.7
Certificates of deposit    
Cash and Cash Equivalents [Line Items]    
Short-term investments, amortized cost 19.0 32.1
Short-term investments, unrealized gain 0.0 0.0
Short-term investments, unrealized loss 0.0 0.0
Short-term investments, estimated fair value 19.0 32.1
U.S. agency obligations    
Cash and Cash Equivalents [Line Items]    
Short-term investments, amortized cost 14.5 14.6
Short-term investments, unrealized gain 0.0 0.0
Short-term investments, unrealized loss (0.5) (0.2)
Short-term investments, estimated fair value 14.0 14.4
Foreign government obligations    
Cash and Cash Equivalents [Line Items]    
Short-term investments, amortized cost 13.5 18.4
Short-term investments, unrealized gain 0.0 0.0
Short-term investments, unrealized loss (0.3) (0.1)
Short-term investments, estimated fair value 13.2 18.3
Supranational securities    
Cash and Cash Equivalents [Line Items]    
Short-term investments, amortized cost 8.0 8.0
Short-term investments, unrealized gain 0.0 0.0
Short-term investments, unrealized loss (0.2) (0.1)
Short-term investments, estimated fair value 7.8 7.9
Cash    
Cash and Cash Equivalents [Line Items]    
Cash and cash equivalents, at carrying value 85.8 142.7
Cash equivalents 85.8 142.7
Money market funds    
Cash and Cash Equivalents [Line Items]    
Cash and cash equivalents, at carrying value 349.7 390.3
Cash equivalents 349.7 $ 390.3
Commercial paper    
Cash and Cash Equivalents [Line Items]    
Cash and cash equivalents, at carrying value 10.0  
Cash equivalents $ 10.0