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Income Taxes - Additional Information (Details) - USD ($) $ in Millions | 12 Months Ended |
--- | --- | ---
Dec. 31, 2024 | Dec. 31, 2023 | Dec. 31, 2022 | Dec. 31, 2021
Operating Loss Carryforwards [Line Items] |  |  |  |
Research credit carryforwards | $ 194.9 | $ 217.1 |  |
Unrecognized tax benefits | 162.7 | 149.8 | $ 127.2 | $ 107.3
Unrecognized tax benefits that would impact effective tax rate | 114.6 |  |  |
Unrecognized tax benefit that would result in adjustment to deferred tax assets | 48.1 |  |  |
Penalties and interest accrued | 5.0 |  |  |
Penalties and interest expense | (1.6) | $ 1.3 | $ 1.7 |
Domestic Tax Jurisdiction |  |  |  |
Operating Loss Carryforwards [Line Items] |  |  |  |
Operating loss carryforwards | 15.8 |  |  |
Operating loss carryforwards, subject to expiration | 4.0 |  |  |
Operating loss carryforwards, not subject to expiration | 11.8 |  |  |
Research credit carryforwards | 192.9 |  |  |
Domestic Tax Jurisdiction | Research Tax Credit Carryforward |  |  |  |
Operating Loss Carryforwards [Line Items] |  |  |  |
Unrecognized tax benefits | 102.9 |  |  |
State and Local Jurisdiction |  |  |  |
Operating Loss Carryforwards [Line Items] |  |  |  |
Operating loss carryforwards | 53.7 |  |  |
Research credit carryforwards | 180.0 |  |  |
State and Local Jurisdiction | Research Tax Credit Carryforward |  |  |  |
Operating Loss Carryforwards [Line Items] |  |  |  |
Unrecognized tax benefits | 49.7 |  |  |
Foreign Tax Jurisdiction |  |  |  |
Operating Loss Carryforwards [Line Items] |  |  |  |
Operating loss carryforwards | 25.2 |  |  |
Tax credit carryforward | $ 0.5 |  |  |

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