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    ACCESSION NUMBER:		0001193125-22-223279
    CONFORMED SUBMISSION TYPE:	8-K
    PUBLIC DOCUMENT COUNT:		15
    CONFORMED PERIOD OF REPORT:	20220817
    ITEM INFORMATION:		Entry into a Material Definitive Agreement
    ITEM INFORMATION:		Termination of a Material Definitive Agreement
    ITEM INFORMATION:		Completion of Acquisition or Disposition of Assets
    ITEM INFORMATION:		Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant
    ITEM INFORMATION:		Unregistered Sales of Equity Securities
    ITEM INFORMATION:		Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers: Compensatory Arrangements of Certain Officers
    ITEM INFORMATION:		Other Events
    ITEM INFORMATION:		Financial Statements and Exhibits
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    DATE AS OF CHANGE:		20220817

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    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			MKS INSTRUMENTS INC
    		CENTRAL INDEX KEY:			0001049502
    		STANDARD INDUSTRIAL CLASSIFICATION:	INDUSTRIAL INSTRUMENTS FOR MEASUREMENT, DISPLAY, AND CONTROL [3823]
    		IRS NUMBER:				042277512
    		STATE OF INCORPORATION:			MA
    		FISCAL YEAR END:			1231

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    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	000-23621
    		FILM NUMBER:		221174357

    	BUSINESS ADDRESS:
    		STREET 1:		2 TECH DRIVE
    		STREET 2:		SUITE 201
    		CITY:			ANDOVER
    		STATE:			MA
    		ZIP:			01810
    		BUSINESS PHONE:		978-645-5500

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    		STREET 2:		SUITE 201
    		CITY:			ANDOVER
    		STATE:			MA
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