    <SEC-DOCUMENT>0000039263-20-000049-index.html : 20200812
    <SEC-HEADER>0000039263-20-000049.hdr.sgml : 20200812
    <ACCEPTANCE-DATETIME>20200812145422
    ACCESSION NUMBER:		0000039263-20-000049
    CONFORMED SUBMISSION TYPE:	S-3ASR
    PUBLIC DOCUMENT COUNT:		14
    FILED AS OF DATE:		20200812
    DATE AS OF CHANGE:		20200812
    EFFECTIVENESS DATE:		20200812

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			CULLEN/FROST BANKERS, INC.
    		CENTRAL INDEX KEY:			0000039263
    		STANDARD INDUSTRIAL CLASSIFICATION:	NATIONAL COMMERCIAL BANKS [6021]
    		IRS NUMBER:				741751768
    		STATE OF INCORPORATION:			TX
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		S-3ASR
    		SEC ACT:		1933 Act
    		SEC FILE NUMBER:	333-244971
    		FILM NUMBER:		201095203

    	BUSINESS ADDRESS:
    		STREET 1:		111 W HOUSTON ST
    		CITY:			SAN ANTONIO
    		STATE:			TX
    		ZIP:			78205
    		BUSINESS PHONE:		210-220-4011

    	MAIL ADDRESS:
    		STREET 1:		POST OFFICE BOX 1600
    		CITY:			SAN ANTONIO
    		STATE:			TX
    		ZIP:			78296-1600

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	CULLEN FROST BANKERS INC
    		DATE OF NAME CHANGE:	19920703

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	FROST BANK CORP
    		DATE OF NAME CHANGE:	19770823
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>S-3ASR
    <SEQUENCE>1
    <FILENAME>a3q20forms-3shelfregistrat.htm
    <DESCRIPTION>S-3ASR
    <TEXT>
    Document 1 - file: a3q20forms-3shelfregistrat.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-4.4
    <SEQUENCE>2
    <FILENAME>exhibit44-formofcertificat.htm
    <DESCRIPTION>EXHIBIT 4.4 - FORM OF CERTIFICATE REPRESENTING CULLEN/FROST BANKERS, INC. COMMON
    <TEXT>
    Document 2 - file: exhibit44-formofcertificat.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-4.5
    <SEQUENCE>3
    <FILENAME>exhibit45-formofseniordebt.htm
    <DESCRIPTION>EXHIBIT 4.5 - FORM OF SENIOR DEBT SECURITIES INDENTURE BETWEEN CULLEN/FROST BANK
    <TEXT>
    Document 3 - file: exhibit45-formofseniordebt.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-4.6
    <SEQUENCE>4
    <FILENAME>exhibit46-subordinateddebt.htm
    <DESCRIPTION>EXHIBIT 4.6 - SUBORDINATED DEBT SECURITIES INDENTURE, DATED AS OF FEBRUARY 15, 2
    <TEXT>
    Document 4 - file: exhibit46-subordinateddebt.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-4.7
    <SEQUENCE>5
    <FILENAME>exhibit47-firstsupplementa.htm
    <DESCRIPTION>EXHIBIT 4.7 - FIRST SUPPLEMENTAL INDENTURE, DATED AS OF MARCH 17, 2017
    <TEXT>
    Document 5 - file: exhibit47-firstsupplementa.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-5.1
    <SEQUENCE>6
    <FILENAME>exhibit51-opinionofsulliva.htm
    <DESCRIPTION>EXHIBIT 5.1 - OPINION OF SULLIVAN & CROMWELL LLP
    <TEXT>
    Document 6 - file: exhibit51-opinionofsulliva.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-5.2
    <SEQUENCE>7
    <FILENAME>exhibit52-opinionofjameslw.htm
    <DESCRIPTION>EXHIBIT 5.2 - OPINION OF JAMES L. WATERS
    <TEXT>
    Document 7 - file: exhibit52-opinionofjameslw.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-23.1
    <SEQUENCE>8
    <FILENAME>exhibit231-consentofernsty.htm
    <DESCRIPTION>EXHIBIT 23.1 - CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
    <TEXT>
    Document 8 - file: exhibit231-consentofernsty.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-24.1
    <SEQUENCE>9
    <FILENAME>exhibit241-powerofattorney.htm
    <DESCRIPTION>EXHIBIT 24.1 - POWER OF ATTORNEY
    <TEXT>
    Document 9 - file: exhibit241-powerofattorney.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-25.1
    <SEQUENCE>10
    <FILENAME>exhibit251-formtx1bnymxfor.htm
    <DESCRIPTION>EXHIBIT 25.1 - FORM T-1 BNYM - FORM OF SENIOR DEBT SECURITIES
    <TEXT>
    Document 10 - file: exhibit251-formtx1bnymxfor.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-25.2
    <SEQUENCE>11
    <FILENAME>exhibit252-formtx1bnymxsub.htm
    <DESCRIPTION>EXHIBIT 25.2 - FORM T-1 BNYM - SUBORDINATED DEBT SECURITIES
    <TEXT>
    Document 11 - file: exhibit252-formtx1bnymxsub.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>12
    <FILENAME>cfrformofcertificate72020.jpg
    <TEXT>
    Document 12 - file: cfrformofcertificate72020.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>13
    <FILENAME>cfrimagefors3.jpg
    <TEXT>
    Document 13 - file: cfrimagefors3.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>14
    <FILENAME>cfrimagefors3a01.jpg
    <TEXT>
    Document 14 - file: cfrimagefors3a01.jpg

    </DOCUMENT>
    </SEC-DOCUMENT>