<?xml version="1.0" encoding="us-ascii"?>
<!--XBRL document created with Toppan Merrill Bridge  9.6.7908.23199 -->
<!--Based on XBRL 2.1-->
<!--Created on: 11/1/2021 7:58:10 PM-->
<!--Modified on: 11/1/2021 7:58:10 PM-->
<link:linkbase xmlns="http://www.xbrl.org/2003/linkbase" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:xlink="http://www.w3.org/1999/xlink" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd" xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xbrli="http://www.xbrl.org/2003/instance">
  <roleRef xlink:type="simple" xlink:href="adc-20210930.xsd#StatementCondensedConsolidatedBalanceSheets" roleURI="http://www.agreerealty.com/role/StatementCondensedConsolidatedBalanceSheets" />
  <roleRef xlink:type="simple" xlink:href="adc-20210930.xsd#StatementCondensedConsolidatedStatementsOfOperationsAndComprehensiveIncome" roleURI="http://www.agreerealty.com/role/StatementCondensedConsolidatedStatementsOfOperationsAndComprehensiveIncome" />
  <roleRef xlink:type="simple" xlink:href="adc-20210930.xsd#StatementConsolidatedStatementsOfIncomeAndComprehensiveIncomeCalc2" roleURI="http://www.agreerealty.com/role/StatementConsolidatedStatementsOfIncomeAndComprehensiveIncomeCalc2" />
  <roleRef xlink:type="simple" xlink:href="adc-20210930.xsd#StatementCondensedConsolidatedStatementsOfCashFlows" roleURI="http://www.agreerealty.com/role/StatementCondensedConsolidatedStatementsOfCashFlows" />
  <roleRef xlink:type="simple" xlink:href="adc-20210930.xsd#DisclosureSummaryOfSignificantAccountingPoliciesRealEstatePropertiesDetails" roleURI="http://www.agreerealty.com/role/DisclosureSummaryOfSignificantAccountingPoliciesRealEstatePropertiesDetails" />
  <roleRef xlink:type="simple" xlink:href="adc-20210930.xsd#DisclosureSummaryOfSignificantAccountingPoliciesFutureAmortizationOfDeferredExpensesDetails" roleURI="http://www.agreerealty.com/role/DisclosureSummaryOfSignificantAccountingPoliciesFutureAmortizationOfDeferredExpensesDetails" />
  <roleRef xlink:type="simple" xlink:href="adc-20210930.xsd#DisclosureSummaryOfSignificantAccountingPoliciesReconciliationOfCashAndCashEquivalentsAndCashHeldInEscrowDetails" roleURI="http://www.agreerealty.com/role/DisclosureSummaryOfSignificantAccountingPoliciesReconciliationOfCashAndCashEquivalentsAndCashHeldInEscrowDetails" />
  <roleRef xlink:type="simple" xlink:href="adc-20210930.xsd#DisclosureSummaryOfSignificantAccountingPoliciesEarningsPerShareDetails" roleURI="http://www.agreerealty.com/role/DisclosureSummaryOfSignificantAccountingPoliciesEarningsPerShareDetails" />
  <roleRef xlink:type="simple" xlink:href="adc-20210930.xsd#DisclosureLeasesTenantLeasesDetails" roleURI="http://www.agreerealty.com/role/DisclosureLeasesTenantLeasesDetails" />
  <roleRef xlink:type="simple" xlink:href="adc-20210930.xsd#DisclosureLeasesLandLeaseObligationsDetails" roleURI="http://www.agreerealty.com/role/DisclosureLeasesLandLeaseObligationsDetails" />
  <roleRef xlink:type="simple" xlink:href="adc-20210930.xsd#DisclosureLeasesLandLeaseObligationsDetailsCalc2" roleURI="http://www.agreerealty.com/role/DisclosureLeasesLandLeaseObligationsDetailsCalc2" />
  <roleRef xlink:type="simple" xlink:href="adc-20210930.xsd#DisclosureDebtMortgagesPayableDetails" roleURI="http://www.agreerealty.com/role/DisclosureDebtMortgagesPayableDetails" />
  <roleRef xlink:type="simple" xlink:href="adc-20210930.xsd#DisclosureDebtSeniorUnsecuredNotesDetails" roleURI="http://www.agreerealty.com/role/DisclosureDebtSeniorUnsecuredNotesDetails" />
  <roleRef xlink:type="simple" xlink:href="adc-20210930.xsd#DisclosureDebtDebtMaturitiesDetails" roleURI="http://www.agreerealty.com/role/DisclosureDebtDebtMaturitiesDetails" />
  <roleRef xlink:type="simple" xlink:href="adc-20210930.xsd#DisclosureDerivativeInstrumentsAndHedgingActivityOffsettingOfDerivativeAssetsAndLiabilitiesDetails" roleURI="http://www.agreerealty.com/role/DisclosureDerivativeInstrumentsAndHedgingActivityOffsettingOfDerivativeAssetsAndLiabilitiesDetails" />
  <link:roleRef xlink:type="simple" xlink:href="adc-20210930.xsd#DisclosureRealEstateInvestments" roleURI="http://www.agreerealty.com/role/DisclosureRealEstateInvestments" />
  <link:roleRef xlink:type="simple" xlink:href="adc-20210930.xsd#DisclosureCommonAndPreferredStock" roleURI="http://www.agreerealty.com/role/DisclosureCommonAndPreferredStock" />
  <link:roleRef xlink:type="simple" xlink:href="adc-20210930.xsd#DisclosureSummaryOfSignificantAccountingPoliciesAmortizationOfDeferredExpensesDetails" roleURI="http://www.agreerealty.com/role/DisclosureSummaryOfSignificantAccountingPoliciesAmortizationOfDeferredExpensesDetails" />
  <link:roleRef xlink:type="simple" xlink:href="adc-20210930.xsd#DisclosureSummaryOfSignificantAccountingPolicies" roleURI="http://www.agreerealty.com/role/DisclosureSummaryOfSignificantAccountingPolicies" />
  <calculationLink xlink:role="http://www.agreerealty.com/role/StatementCondensedConsolidatedBalanceSheets" xlink:type="extended" xlink:title="00100 - Statement - CONDENSED CONSOLIDATED BALANCE SHEETS">
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_Assets" xlink:label="loc_us-gaap_Assets" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RealEstateInvestmentPropertyNet" xlink:label="us-gaap_RealEstateInvestmentPropertyNet_637713934742843147" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets" xlink:to="us-gaap_RealEstateInvestmentPropertyNet_637713934742843147" order="1" use="optional" weight="1" />
    <loc xlink:type="locator" xlink:href="adc-20210930.xsd#adc_RealEstateInvestmentPropertyExcludingPropertyUnderDevelopmentNetOfAccumulatedDepreciation" xlink:label="adc_RealEstateInvestmentPropertyExcludingPropertyUnderDevelopmentNetOfAccumulatedDepreciation_637713934742843147" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_RealEstateInvestmentPropertyNet_637713934742843147" xlink:to="adc_RealEstateInvestmentPropertyExcludingPropertyUnderDevelopmentNetOfAccumulatedDepreciation_637713934742843147" order="1" use="optional" weight="1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_Land" xlink:label="us-gaap_Land_637713934742843147" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="adc_RealEstateInvestmentPropertyExcludingPropertyUnderDevelopmentNetOfAccumulatedDepreciation_637713934742843147" xlink:to="us-gaap_Land_637713934742843147" order="1" use="optional" weight="1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InvestmentBuildingAndBuildingImprovements" xlink:label="us-gaap_InvestmentBuildingAndBuildingImprovements_637713934742853107" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="adc_RealEstateInvestmentPropertyExcludingPropertyUnderDevelopmentNetOfAccumulatedDepreciation_637713934742843147" xlink:to="us-gaap_InvestmentBuildingAndBuildingImprovements_637713934742853107" order="2" use="optional" weight="1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RealEstateInvestmentPropertyAccumulatedDepreciation" xlink:label="us-gaap_RealEstateInvestmentPropertyAccumulatedDepreciation_637713934742853107" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="adc_RealEstateInvestmentPropertyExcludingPropertyUnderDevelopmentNetOfAccumulatedDepreciation_637713934742843147" xlink:to="us-gaap_RealEstateInvestmentPropertyAccumulatedDepreciation_637713934742853107" order="3" use="optional" weight="-1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DevelopmentInProcess" xlink:label="us-gaap_DevelopmentInProcess_637713934742853107" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_RealEstateInvestmentPropertyNet_637713934742843147" xlink:to="us-gaap_DevelopmentInProcess_637713934742853107" order="2" use="optional" weight="1" />
    <loc xlink:type="locator" xlink:href="adc-20210930.xsd#adc_RealEstateHeldForSaleNetTotal" xlink:label="adc_RealEstateHeldForSaleNetTotal_637713934742853107" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets" xlink:to="adc_RealEstateHeldForSaleNetTotal_637713934742853107" order="2" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue" xlink:label="us-gaap_CashAndCashEquivalentsAtCarryingValue_637713934742853107" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets" xlink:to="us-gaap_CashAndCashEquivalentsAtCarryingValue_637713934742853107" order="3" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EscrowDeposit" xlink:label="us-gaap_EscrowDeposit_637713934742853107" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets" xlink:to="us-gaap_EscrowDeposit_637713934742853107" order="4" use="optional" weight="1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccountsReceivableNet" xlink:label="us-gaap_AccountsReceivableNet_637713934742853107" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets" xlink:to="us-gaap_AccountsReceivableNet_637713934742853107" order="5" use="optional" weight="1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetAcquiredInPlaceLeases" xlink:label="us-gaap_FiniteLivedIntangibleAssetAcquiredInPlaceLeases_637713934742853107" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets" xlink:to="us-gaap_FiniteLivedIntangibleAssetAcquiredInPlaceLeases_637713934742853107" order="6" use="optional" weight="1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherAssets" xlink:label="us-gaap_OtherAssets_637713934742863105" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets" xlink:to="us-gaap_OtherAssets_637713934742863105" order="7" use="optional" weight="1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LiabilitiesAndStockholdersEquity" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquity" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest" xlink:label="us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest_637713934742863105" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity" xlink:to="us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest_637713934742863105" order="1" use="optional" weight="1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockholdersEquity" xlink:label="us-gaap_StockholdersEquity_637713934742863105" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest_637713934742863105" xlink:to="us-gaap_StockholdersEquity_637713934742863105" order="1" use="optional" weight="1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStockValue" xlink:label="us-gaap_CommonStockValue_637713934742863105" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_StockholdersEquity_637713934742863105" xlink:to="us-gaap_CommonStockValue_637713934742863105" order="1" use="optional" weight="1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PreferredStockValue" xlink:label="us-gaap_PreferredStockValue_637713934742863105" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_StockholdersEquity_637713934742863105" xlink:to="us-gaap_PreferredStockValue_637713934742863105" order="2" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AdditionalPaidInCapital" xlink:label="us-gaap_AdditionalPaidInCapital_637713934742863105" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_StockholdersEquity_637713934742863105" xlink:to="us-gaap_AdditionalPaidInCapital_637713934742863105" order="3" use="optional" weight="1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccumulatedDistributionsInExcessOfNetIncome" xlink:label="us-gaap_AccumulatedDistributionsInExcessOfNetIncome_637713934742863105" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_StockholdersEquity_637713934742863105" xlink:to="us-gaap_AccumulatedDistributionsInExcessOfNetIncome_637713934742863105" order="4" use="optional" weight="-1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax" xlink:label="us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_637713934742873105" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_StockholdersEquity_637713934742863105" xlink:to="us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_637713934742873105" order="5" use="optional" weight="1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_MinorityInterest" xlink:label="us-gaap_MinorityInterest_637713934742873105" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest_637713934742863105" xlink:to="us-gaap_MinorityInterest_637713934742873105" order="2" use="optional" weight="1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_Liabilities" xlink:label="us-gaap_Liabilities_637713934742873105" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity" xlink:to="us-gaap_Liabilities_637713934742873105" order="2" use="optional" weight="1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SecuredDebt" xlink:label="us-gaap_SecuredDebt_637713934742873105" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_Liabilities_637713934742873105" xlink:to="us-gaap_SecuredDebt_637713934742873105" order="1" use="optional" weight="1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_UnsecuredDebt" xlink:label="us-gaap_UnsecuredDebt_637713934742873105" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_Liabilities_637713934742873105" xlink:to="us-gaap_UnsecuredDebt_637713934742873105" order="2" use="optional" weight="1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SeniorNotes" xlink:label="us-gaap_SeniorNotes_637713934742873105" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_Liabilities_637713934742873105" xlink:to="us-gaap_SeniorNotes_637713934742873105" order="3" use="optional" weight="1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LineOfCredit" xlink:label="us-gaap_LineOfCredit_637713934742883107" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_Liabilities_637713934742873105" xlink:to="us-gaap_LineOfCredit_637713934742883107" order="4" use="optional" weight="1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DividendsPayableCurrentAndNoncurrent" xlink:label="us-gaap_DividendsPayableCurrentAndNoncurrent_637713934742883107" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_Liabilities_637713934742873105" xlink:to="us-gaap_DividendsPayableCurrentAndNoncurrent_637713934742883107" order="5" use="optional" weight="1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccountsPayableAndAccruedLiabilitiesCurrentAndNoncurrent" xlink:label="us-gaap_AccountsPayableAndAccruedLiabilitiesCurrentAndNoncurrent_637713934742883107" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_Liabilities_637713934742873105" xlink:to="us-gaap_AccountsPayableAndAccruedLiabilitiesCurrentAndNoncurrent_637713934742883107" order="6" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BelowMarketLeaseNet" xlink:label="us-gaap_BelowMarketLeaseNet_637713934742883107" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_Liabilities_637713934742873105" xlink:to="us-gaap_BelowMarketLeaseNet_637713934742883107" order="7" use="optional" weight="1" />
  </calculationLink>
  <calculationLink xlink:role="http://www.agreerealty.com/role/StatementCondensedConsolidatedStatementsOfOperationsAndComprehensiveIncome" xlink:type="extended" xlink:title="00200 - Statement - CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE INCOME">
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic" xlink:label="us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic_1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PreferredStockDividendsIncomeStatementImpact" xlink:label="us-gaap_PreferredStockDividendsIncomeStatementImpact_637713934742893229" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic_1" xlink:to="us-gaap_PreferredStockDividendsIncomeStatementImpact_637713934742893229" order="1" use="optional" weight="-1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetIncomeLoss" xlink:label="us-gaap_NetIncomeLoss_637713934742893229" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic_1" xlink:to="us-gaap_NetIncomeLoss_637713934742893229" order="2" use="optional" weight="1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetIncomeLossAttributableToNoncontrollingInterest" xlink:label="us-gaap_NetIncomeLossAttributableToNoncontrollingInterest_637713934742893229" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetIncomeLoss_637713934742893229" xlink:to="us-gaap_NetIncomeLossAttributableToNoncontrollingInterest_637713934742893229" order="1" use="optional" weight="-1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProfitLoss" xlink:label="us-gaap_ProfitLoss_637713934742893229" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetIncomeLoss_637713934742893229" xlink:to="us-gaap_ProfitLoss_637713934742893229" order="2" use="optional" weight="1" priority="3" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingIncomeLoss" xlink:label="us-gaap_OperatingIncomeLoss_637713934742893229" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_ProfitLoss_637713934742893229" xlink:to="us-gaap_OperatingIncomeLoss_637713934742893229" order="1" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_Revenues" xlink:label="us-gaap_Revenues_637713934742893229" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_OperatingIncomeLoss_637713934742893229" xlink:to="us-gaap_Revenues_637713934742893229" order="1" use="optional" weight="1" priority="3" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RevenueFromContractWithCustomerIncludingAssessedTax" xlink:label="us-gaap_RevenueFromContractWithCustomerIncludingAssessedTax_637713934742893229" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_Revenues_637713934742893229" xlink:to="us-gaap_RevenueFromContractWithCustomerIncludingAssessedTax_637713934742893229" order="1" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RevenueNotFromContractWithCustomerOther" xlink:label="us-gaap_RevenueNotFromContractWithCustomerOther_637713934742893229" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_Revenues_637713934742893229" xlink:to="us-gaap_RevenueNotFromContractWithCustomerOther_637713934742893229" order="2" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CostsAndExpenses" xlink:label="us-gaap_CostsAndExpenses_637713934742903113" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_OperatingIncomeLoss_637713934742893229" xlink:to="us-gaap_CostsAndExpenses_637713934742903113" order="2" use="optional" weight="-1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ImpairmentOfLongLivedAssetsHeldForUse" xlink:label="us-gaap_ImpairmentOfLongLivedAssetsHeldForUse_637713934742903113" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_CostsAndExpenses_637713934742903113" xlink:to="us-gaap_ImpairmentOfLongLivedAssetsHeldForUse_637713934742903113" order="1" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DepreciationAndAmortization" xlink:label="us-gaap_DepreciationAndAmortization_637713934742903113" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_CostsAndExpenses_637713934742903113" xlink:to="us-gaap_DepreciationAndAmortization_637713934742903113" order="2" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingLeaseInitialDirectCostExpenseOverTerm" xlink:label="us-gaap_OperatingLeaseInitialDirectCostExpenseOverTerm_637713934742903113" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_CostsAndExpenses_637713934742903113" xlink:to="us-gaap_OperatingLeaseInitialDirectCostExpenseOverTerm_637713934742903113" order="3" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_GeneralAndAdministrativeExpense" xlink:label="us-gaap_GeneralAndAdministrativeExpense_637713934742903113" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_CostsAndExpenses_637713934742903113" xlink:to="us-gaap_GeneralAndAdministrativeExpense_637713934742903113" order="4" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingLeaseExpense" xlink:label="us-gaap_OperatingLeaseExpense_637713934742903113" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_CostsAndExpenses_637713934742903113" xlink:to="us-gaap_OperatingLeaseExpense_637713934742903113" order="5" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RealEstateTaxExpense" xlink:label="us-gaap_RealEstateTaxExpense_637713934742903113" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_CostsAndExpenses_637713934742903113" xlink:to="us-gaap_RealEstateTaxExpense_637713934742903113" order="6" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_GainsLossesOnSalesOfAssets" xlink:label="us-gaap_GainsLossesOnSalesOfAssets_637713934742903113" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_OperatingIncomeLoss_637713934742893229" xlink:to="us-gaap_GainsLossesOnSalesOfAssets_637713934742903113" order="3" use="optional" weight="1" priority="3" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeTaxExpenseBenefit" xlink:label="us-gaap_IncomeTaxExpenseBenefit_637713934742913107" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_ProfitLoss_637713934742893229" xlink:to="us-gaap_IncomeTaxExpenseBenefit_637713934742913107" order="2" use="optional" weight="-1" priority="2" />
    <loc xlink:type="locator" xlink:href="adc-20210930.xsd#adc_GainLossOnEarlyExtinguishmentOfDebtAndSettlementOfRelatedInterestRateSwaps" xlink:label="adc_GainLossOnEarlyExtinguishmentOfDebtAndSettlementOfRelatedInterestRateSwaps_637713934742913107" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_ProfitLoss_637713934742893229" xlink:to="adc_GainLossOnEarlyExtinguishmentOfDebtAndSettlementOfRelatedInterestRateSwaps_637713934742913107" order="3" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InterestExpense" xlink:label="us-gaap_InterestExpense_637713934742913107" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_ProfitLoss_637713934742893229" xlink:to="us-gaap_InterestExpense_637713934742913107" order="4" use="optional" weight="-1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherNonoperatingIncomeExpense" xlink:label="us-gaap_OtherNonoperatingIncomeExpense_637713934742913107" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_ProfitLoss_637713934742893229" xlink:to="us-gaap_OtherNonoperatingIncomeExpense_637713934742913107" order="5" use="optional" weight="1" priority="2" />
  </calculationLink>
  <calculationLink xlink:role="http://www.agreerealty.com/role/StatementConsolidatedStatementsOfIncomeAndComprehensiveIncomeCalc2" xlink:type="extended" xlink:title="00201 - Statement - CONSOLIDATED STATEMENTS OF INCOME AND COMPREHENSIVE INCOME (Calc2)">
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ComprehensiveIncomeNetOfTax" xlink:label="us-gaap_ComprehensiveIncomeNetOfTax_636909247033970716" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterest" xlink:label="us-gaap_ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterest_637713934742913107" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_ComprehensiveIncomeNetOfTax_636909247033970716" xlink:to="us-gaap_ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterest_637713934742913107" order="1" use="optional" weight="1" priority="3" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProfitLoss" xlink:label="us-gaap_ProfitLoss_637713934742913107" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterest_637713934742913107" xlink:to="us-gaap_ProfitLoss_637713934742913107" order="1" use="optional" weight="1" priority="1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTax" xlink:label="us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTax_637713934742923105" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterest_637713934742913107" xlink:to="us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTax_637713934742923105" order="2" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="adc-20210930.xsd#adc_OtherComprehensiveIncomeLossCashFlowHedgeGainLossFromSettlement" xlink:label="adc_OtherComprehensiveIncomeLossCashFlowHedgeGainLossFromSettlement_637713934742923105" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterest_637713934742913107" xlink:to="adc_OtherComprehensiveIncomeLossCashFlowHedgeGainLossFromSettlement_637713934742923105" order="3" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ComprehensiveIncomeNetOfTaxAttributableToNoncontrollingInterest" xlink:label="us-gaap_ComprehensiveIncomeNetOfTaxAttributableToNoncontrollingInterest_637713934742923105" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_ComprehensiveIncomeNetOfTax_636909247033970716" xlink:to="us-gaap_ComprehensiveIncomeNetOfTaxAttributableToNoncontrollingInterest_637713934742923105" order="2" use="optional" weight="-1" priority="3" />
  </calculationLink>
  <calculationLink xlink:role="http://www.agreerealty.com/role/StatementCondensedConsolidatedStatementsOfCashFlows" xlink:type="extended" xlink:title="00400 - Statement - CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS">
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect" xlink:label="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities" xlink:label="us-gaap_NetCashProvidedByUsedInOperatingActivities_637713934742923105" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect" xlink:to="us-gaap_NetCashProvidedByUsedInOperatingActivities_637713934742923105" order="1" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProfitLoss" xlink:label="us-gaap_ProfitLoss_637713934742923105" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetCashProvidedByUsedInOperatingActivities_637713934742923105" xlink:to="us-gaap_ProfitLoss_637713934742923105" order="1" use="optional" weight="1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AmortizationOfAboveAndBelowMarketLeases" xlink:label="us-gaap_AmortizationOfAboveAndBelowMarketLeases_637713934742923105" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetCashProvidedByUsedInOperatingActivities_637713934742923105" xlink:to="us-gaap_AmortizationOfAboveAndBelowMarketLeases_637713934742923105" order="2" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_WriteOffOfDeferredDebtIssuanceCost" xlink:label="us-gaap_WriteOffOfDeferredDebtIssuanceCost_637713934742923105" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetCashProvidedByUsedInOperatingActivities_637713934742923105" xlink:to="us-gaap_WriteOffOfDeferredDebtIssuanceCost_637713934742923105" order="3" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DepreciationAndAmortization" xlink:label="us-gaap_DepreciationAndAmortization_637713934742923105" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetCashProvidedByUsedInOperatingActivities_637713934742923105" xlink:to="us-gaap_DepreciationAndAmortization_637713934742923105" order="4" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ImpairmentOfLongLivedAssetsHeldForUse" xlink:label="us-gaap_ImpairmentOfLongLivedAssetsHeldForUse_637713934742933106" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetCashProvidedByUsedInOperatingActivities_637713934742923105" xlink:to="us-gaap_ImpairmentOfLongLivedAssetsHeldForUse_637713934742933106" order="5" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="adc-20210930.xsd#adc_GainLossOnSettlementOfInterestRateSwaps" xlink:label="adc_GainLossOnSettlementOfInterestRateSwaps_637713934742933106" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetCashProvidedByUsedInOperatingActivities_637713934742923105" xlink:to="adc_GainLossOnSettlementOfInterestRateSwaps_637713934742933106" order="6" use="optional" weight="-1" priority="3" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AmortizationOfFinancingCostsAndDiscounts" xlink:label="us-gaap_AmortizationOfFinancingCostsAndDiscounts_637713934742933106" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetCashProvidedByUsedInOperatingActivities_637713934742923105" xlink:to="us-gaap_AmortizationOfFinancingCostsAndDiscounts_637713934742933106" order="7" use="optional" weight="1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ShareBasedCompensation" xlink:label="us-gaap_ShareBasedCompensation_637713934742933106" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetCashProvidedByUsedInOperatingActivities_637713934742923105" xlink:to="us-gaap_ShareBasedCompensation_637713934742933106" order="8" use="optional" weight="1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_GainLossOnDispositionOfAssets1" xlink:label="us-gaap_GainLossOnDispositionOfAssets1_637713934742933106" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetCashProvidedByUsedInOperatingActivities_637713934742923105" xlink:to="us-gaap_GainLossOnDispositionOfAssets1_637713934742933106" order="9" use="optional" weight="-1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncreaseDecreaseInAccountsReceivable" xlink:label="us-gaap_IncreaseDecreaseInAccountsReceivable_637713934742933106" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetCashProvidedByUsedInOperatingActivities_637713934742923105" xlink:to="us-gaap_IncreaseDecreaseInAccountsReceivable_637713934742933106" order="10" use="optional" weight="-1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncreaseDecreaseInOtherOperatingAssets" xlink:label="us-gaap_IncreaseDecreaseInOtherOperatingAssets_637713934742933106" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetCashProvidedByUsedInOperatingActivities_637713934742923105" xlink:to="us-gaap_IncreaseDecreaseInOtherOperatingAssets_637713934742933106" order="11" use="optional" weight="-1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncreaseDecreaseInAccountsPayable" xlink:label="us-gaap_IncreaseDecreaseInAccountsPayable_637713934742933106" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetCashProvidedByUsedInOperatingActivities_637713934742923105" xlink:to="us-gaap_IncreaseDecreaseInAccountsPayable_637713934742933106" order="12" use="optional" weight="1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities" xlink:label="us-gaap_NetCashProvidedByUsedInFinancingActivities_637713934742943106" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect" xlink:to="us-gaap_NetCashProvidedByUsedInFinancingActivities_637713934742943106" order="2" use="optional" weight="1" priority="1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProceedsFromIssuanceOfCommonStock" xlink:label="us-gaap_ProceedsFromIssuanceOfCommonStock_637713934742943106" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetCashProvidedByUsedInFinancingActivities_637713934742943106" xlink:to="us-gaap_ProceedsFromIssuanceOfCommonStock_637713934742943106" order="1" use="optional" weight="1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PaymentsForRepurchaseOfCommonStock" xlink:label="us-gaap_PaymentsForRepurchaseOfCommonStock_637713934742943106" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetCashProvidedByUsedInFinancingActivities_637713934742943106" xlink:to="us-gaap_PaymentsForRepurchaseOfCommonStock_637713934742943106" order="2" use="optional" weight="-1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProceedsFromRepaymentsOfLinesOfCredit" xlink:label="us-gaap_ProceedsFromRepaymentsOfLinesOfCredit_637713934742943106" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetCashProvidedByUsedInFinancingActivities_637713934742943106" xlink:to="us-gaap_ProceedsFromRepaymentsOfLinesOfCredit_637713934742943106" order="3" use="optional" weight="1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RepaymentsOfSecuredDebt" xlink:label="us-gaap_RepaymentsOfSecuredDebt_637713934742943106" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetCashProvidedByUsedInFinancingActivities_637713934742943106" xlink:to="us-gaap_RepaymentsOfSecuredDebt_637713934742943106" order="4" use="optional" weight="-1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RepaymentsOfUnsecuredDebt" xlink:label="us-gaap_RepaymentsOfUnsecuredDebt_637713934742943106" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetCashProvidedByUsedInFinancingActivities_637713934742943106" xlink:to="us-gaap_RepaymentsOfUnsecuredDebt_637713934742943106" order="5" use="optional" weight="-1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProceedsFromUnsecuredNotesPayable" xlink:label="us-gaap_ProceedsFromUnsecuredNotesPayable_637713934742943106" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetCashProvidedByUsedInFinancingActivities_637713934742943106" xlink:to="us-gaap_ProceedsFromUnsecuredNotesPayable_637713934742943106" order="6" use="optional" weight="1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PaymentsOfDividendsCommonStock" xlink:label="us-gaap_PaymentsOfDividendsCommonStock_637713934742953104" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetCashProvidedByUsedInFinancingActivities_637713934742943106" xlink:to="us-gaap_PaymentsOfDividendsCommonStock_637713934742953104" order="7" use="optional" weight="-1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PaymentsToMinorityShareholders" xlink:label="us-gaap_PaymentsToMinorityShareholders_637713934742953104" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetCashProvidedByUsedInFinancingActivities_637713934742943106" xlink:to="us-gaap_PaymentsToMinorityShareholders_637713934742953104" order="8" use="optional" weight="-1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PaymentsOfFinancingCosts" xlink:label="us-gaap_PaymentsOfFinancingCosts_637713934742953104" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetCashProvidedByUsedInFinancingActivities_637713934742943106" xlink:to="us-gaap_PaymentsOfFinancingCosts_637713934742953104" order="9" use="optional" weight="-1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProceedsFromIssuanceOfPreferredStockAndPreferenceStock" xlink:label="us-gaap_ProceedsFromIssuanceOfPreferredStockAndPreferenceStock_637713934742953104" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetCashProvidedByUsedInFinancingActivities_637713934742943106" xlink:to="us-gaap_ProceedsFromIssuanceOfPreferredStockAndPreferenceStock_637713934742953104" order="10" use="optional" weight="1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities" xlink:label="us-gaap_NetCashProvidedByUsedInInvestingActivities_637713934742953104" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect" xlink:to="us-gaap_NetCashProvidedByUsedInInvestingActivities_637713934742953104" order="3" use="optional" weight="1" priority="1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PaymentsToAcquireRealEstate" xlink:label="us-gaap_PaymentsToAcquireRealEstate_637713934742953104" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetCashProvidedByUsedInInvestingActivities_637713934742953104" xlink:to="us-gaap_PaymentsToAcquireRealEstate_637713934742953104" order="1" use="optional" weight="-1" />
    <loc xlink:type="locator" xlink:href="adc-20210930.xsd#adc_PaymentsForProceedsFromDevelopRealEstateAssets" xlink:label="adc_PaymentsForProceedsFromDevelopRealEstateAssets_637713934742963103" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetCashProvidedByUsedInInvestingActivities_637713934742953104" xlink:to="adc_PaymentsForProceedsFromDevelopRealEstateAssets_637713934742963103" order="2" use="optional" weight="-1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PaymentsForLeasingCosts" xlink:label="us-gaap_PaymentsForLeasingCosts_637713934742963103" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetCashProvidedByUsedInInvestingActivities_637713934742953104" xlink:to="us-gaap_PaymentsForLeasingCosts_637713934742963103" order="3" use="optional" weight="-1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProceedsFromSaleOfProductiveAssets" xlink:label="us-gaap_ProceedsFromSaleOfProductiveAssets_637713934742963103" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetCashProvidedByUsedInInvestingActivities_637713934742953104" xlink:to="us-gaap_ProceedsFromSaleOfProductiveAssets_637713934742963103" order="4" use="optional" weight="1" />
  </calculationLink>
  <calculationLink xlink:role="http://www.agreerealty.com/role/DisclosureSummaryOfSignificantAccountingPoliciesRealEstatePropertiesDetails" xlink:type="extended" xlink:title="40201 - Disclosure - Summary of Significant Accounting Policies - Real Estate Properties (Details)">
    <loc xlink:type="locator" xlink:href="adc-20210930.xsd#adc_RealEstateHeldForSaleNetTotal" xlink:label="adc_RealEstateHeldForSaleNetTotal" />
    <loc xlink:type="locator" xlink:href="adc-20210930.xsd#adc_RealEstateHeldForSaleGross" xlink:label="adc_RealEstateHeldForSaleGross_637713934742963103" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="adc_RealEstateHeldForSaleNetTotal" xlink:to="adc_RealEstateHeldForSaleGross_637713934742963103" order="1" use="optional" weight="1" />
    <loc xlink:type="locator" xlink:href="adc-20210930.xsd#adc_RealEstateHeldForSaleLeaseLiability" xlink:label="adc_RealEstateHeldForSaleLeaseLiability_637713934742963103" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="adc_RealEstateHeldForSaleGross_637713934742963103" xlink:to="adc_RealEstateHeldForSaleLeaseLiability_637713934742963103" order="1" use="optional" weight="-1" priority="2" />
    <loc xlink:type="locator" xlink:href="adc-20210930.xsd#adc_RealEstateHeldForSaleBuilding" xlink:label="adc_RealEstateHeldForSaleBuilding_637713934742963103" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="adc_RealEstateHeldForSaleGross_637713934742963103" xlink:to="adc_RealEstateHeldForSaleBuilding_637713934742963103" order="2" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="adc-20210930.xsd#adc_RealEstateHeldForSaleLand" xlink:label="adc_RealEstateHeldForSaleLand_637713934742973103" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="adc_RealEstateHeldForSaleGross_637713934742963103" xlink:to="adc_RealEstateHeldForSaleLand_637713934742973103" order="3" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="adc-20210930.xsd#adc_RealEstateHeldForSaleLeaseIntangibles" xlink:label="adc_RealEstateHeldForSaleLeaseIntangibles_637713934742973103" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="adc_RealEstateHeldForSaleGross_637713934742963103" xlink:to="adc_RealEstateHeldForSaleLeaseIntangibles_637713934742973103" order="4" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="adc-20210930.xsd#adc_RealEstateHeldForSaleAccumulatedDepreciation" xlink:label="adc_RealEstateHeldForSaleAccumulatedDepreciation_637713934742973103" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="adc_RealEstateHeldForSaleNetTotal" xlink:to="adc_RealEstateHeldForSaleAccumulatedDepreciation_637713934742973103" order="2" use="optional" weight="-1" priority="2" />
  </calculationLink>
  <calculationLink xlink:role="http://www.agreerealty.com/role/DisclosureSummaryOfSignificantAccountingPoliciesFutureAmortizationOfDeferredExpensesDetails" xlink:type="extended" xlink:title="40203 - Disclosure - Summary of Significant Accounting Policies - Future Amortization of Deferred Expenses (Details)">
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BelowMarketLeaseNet" xlink:label="loc_us-gaap_BelowMarketLeaseNet" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BelowMarketLeaseAmortizationIncomeRemainderOfFiscalYear" xlink:label="us-gaap_BelowMarketLeaseAmortizationIncomeRemainderOfFiscalYear_637713934742973103" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BelowMarketLeaseNet" xlink:to="us-gaap_BelowMarketLeaseAmortizationIncomeRemainderOfFiscalYear_637713934742973103" order="1" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BelowMarketLeaseAmortizationIncomeNextTwelveMonths" xlink:label="us-gaap_BelowMarketLeaseAmortizationIncomeNextTwelveMonths_637713934742973103" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BelowMarketLeaseNet" xlink:to="us-gaap_BelowMarketLeaseAmortizationIncomeNextTwelveMonths_637713934742973103" order="2" use="optional" weight="1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BelowMarketLeaseAmortizationIncomeYearTwo" xlink:label="us-gaap_BelowMarketLeaseAmortizationIncomeYearTwo_637713934742973103" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BelowMarketLeaseNet" xlink:to="us-gaap_BelowMarketLeaseAmortizationIncomeYearTwo_637713934742973103" order="3" use="optional" weight="1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BelowMarketLeaseAmortizationIncomeYearThree" xlink:label="us-gaap_BelowMarketLeaseAmortizationIncomeYearThree_637713934742973103" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BelowMarketLeaseNet" xlink:to="us-gaap_BelowMarketLeaseAmortizationIncomeYearThree_637713934742973103" order="4" use="optional" weight="1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BelowMarketLeaseAmortizationIncomeYearFour" xlink:label="us-gaap_BelowMarketLeaseAmortizationIncomeYearFour_637713934742973103" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BelowMarketLeaseNet" xlink:to="us-gaap_BelowMarketLeaseAmortizationIncomeYearFour_637713934742973103" order="5" use="optional" weight="1" />
    <loc xlink:type="locator" xlink:href="adc-20210930.xsd#adc_BelowMarketLeaseAmortizationIncomeYearFiveAndAfterYearFive" xlink:label="adc_BelowMarketLeaseAmortizationIncomeYearFiveAndAfterYearFive_637713934742983108" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BelowMarketLeaseNet" xlink:to="adc_BelowMarketLeaseAmortizationIncomeYearFiveAndAfterYearFive_637713934742983108" order="6" use="optional" weight="1" priority="1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsNet" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsNet" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear" xlink:label="us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear_637713934742983108" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet" xlink:to="us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear_637713934742983108" order="1" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths" xlink:label="us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_637713934742983108" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet" xlink:to="us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_637713934742983108" order="2" use="optional" weight="1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo" xlink:label="us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_637713934742983108" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet" xlink:to="us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_637713934742983108" order="3" use="optional" weight="1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree" xlink:label="us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_637713934742983108" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet" xlink:to="us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_637713934742983108" order="4" use="optional" weight="1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour" xlink:label="us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_637713934742983108" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet" xlink:to="us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_637713934742983108" order="5" use="optional" weight="1" />
    <loc xlink:type="locator" xlink:href="adc-20210930.xsd#adc_FiniteLivedIntangibleAssetExpectedAmortizationYearFiveAndAfterYearFive" xlink:label="adc_FiniteLivedIntangibleAssetExpectedAmortizationYearFiveAndAfterYearFive_637713934742993177" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet" xlink:to="adc_FiniteLivedIntangibleAssetExpectedAmortizationYearFiveAndAfterYearFive_637713934742993177" order="6" use="optional" weight="1" priority="1" />
  </calculationLink>
  <calculationLink xlink:role="http://www.agreerealty.com/role/DisclosureSummaryOfSignificantAccountingPoliciesReconciliationOfCashAndCashEquivalentsAndCashHeldInEscrowDetails" xlink:type="extended" xlink:title="40204 - Disclosure - Summary of Significant Accounting Policies - Reconciliation of cash and cash equivalents and cash held in escrow - (Details)">
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" xlink:label="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EscrowDeposit" xlink:label="us-gaap_EscrowDeposit_637713934742993177" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" xlink:to="us-gaap_EscrowDeposit_637713934742993177" order="1" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue" xlink:label="us-gaap_CashAndCashEquivalentsAtCarryingValue_637713934742993177" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" xlink:to="us-gaap_CashAndCashEquivalentsAtCarryingValue_637713934742993177" order="2" use="optional" weight="1" priority="2" />
  </calculationLink>
  <calculationLink xlink:role="http://www.agreerealty.com/role/DisclosureSummaryOfSignificantAccountingPoliciesEarningsPerShareDetails" xlink:type="extended" xlink:title="40205 - Disclosure - Summary of Significant Accounting Policies - Earnings per Share (Details)">
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetIncomeLossAvailableToCommonStockholdersDiluted" xlink:label="us-gaap_NetIncomeLossAvailableToCommonStockholdersDiluted" />
    <loc xlink:type="locator" xlink:href="adc-20210930.xsd#adc_NetIncomeLossUnvestedRestrictedStock" xlink:label="adc_NetIncomeLossUnvestedRestrictedStock_637713934742993177" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetIncomeLossAvailableToCommonStockholdersDiluted" xlink:to="adc_NetIncomeLossUnvestedRestrictedStock_637713934742993177" order="1" use="optional" weight="-1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic" xlink:label="us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic_637713934742993177" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_NetIncomeLossAvailableToCommonStockholdersDiluted" xlink:to="us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic_637713934742993177" order="2" use="optional" weight="1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding" xlink:label="us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncrementalCommonSharesAttributableToEquityForwardAgreements" xlink:label="us-gaap_IncrementalCommonSharesAttributableToEquityForwardAgreements_637713934743003111" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding" xlink:to="us-gaap_IncrementalCommonSharesAttributableToEquityForwardAgreements_637713934743003111" order="1" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements" xlink:label="us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements_637713934743003111" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding" xlink:to="us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements_637713934743003111" order="2" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingBasic" xlink:label="us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_637713934743003111" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding" xlink:to="us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_637713934743003111" order="3" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_WeightedAverageNumberOfSharesIssuedBasic" xlink:label="us-gaap_WeightedAverageNumberOfSharesIssuedBasic_637713934743003111" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_637713934743003111" xlink:to="us-gaap_WeightedAverageNumberOfSharesIssuedBasic_637713934743003111" order="1" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_WeightedAverageNumberOfSharesRestrictedStock" xlink:label="us-gaap_WeightedAverageNumberOfSharesRestrictedStock_637713934743003111" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_637713934743003111" xlink:to="us-gaap_WeightedAverageNumberOfSharesRestrictedStock_637713934743003111" order="2" use="optional" weight="-1" priority="2" />
  </calculationLink>
  <calculationLink xlink:role="http://www.agreerealty.com/role/DisclosureLeasesTenantLeasesDetails" xlink:type="extended" xlink:title="40301 - Disclosure - Leases - Tenant Leases (Details)">
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LessorOperatingLeasePaymentsToBeReceived" xlink:label="us-gaap_LessorOperatingLeasePaymentsToBeReceived" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LessorOperatingLeasePaymentsToBeReceivedRemainderOfFiscalYear" xlink:label="us-gaap_LessorOperatingLeasePaymentsToBeReceivedRemainderOfFiscalYear_637713934743003111" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_LessorOperatingLeasePaymentsToBeReceived" xlink:to="us-gaap_LessorOperatingLeasePaymentsToBeReceivedRemainderOfFiscalYear_637713934743003111" order="1" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LessorOperatingLeasePaymentsToBeReceivedNextTwelveMonths" xlink:label="us-gaap_LessorOperatingLeasePaymentsToBeReceivedNextTwelveMonths_637713934743003111" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_LessorOperatingLeasePaymentsToBeReceived" xlink:to="us-gaap_LessorOperatingLeasePaymentsToBeReceivedNextTwelveMonths_637713934743003111" order="2" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LessorOperatingLeasePaymentsToBeReceivedTwoYears" xlink:label="us-gaap_LessorOperatingLeasePaymentsToBeReceivedTwoYears_637713934743013107" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_LessorOperatingLeasePaymentsToBeReceived" xlink:to="us-gaap_LessorOperatingLeasePaymentsToBeReceivedTwoYears_637713934743013107" order="3" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LessorOperatingLeasePaymentsToBeReceivedThreeYears" xlink:label="us-gaap_LessorOperatingLeasePaymentsToBeReceivedThreeYears_637713934743013107" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_LessorOperatingLeasePaymentsToBeReceived" xlink:to="us-gaap_LessorOperatingLeasePaymentsToBeReceivedThreeYears_637713934743013107" order="4" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LessorOperatingLeasePaymentsToBeReceivedFourYears" xlink:label="us-gaap_LessorOperatingLeasePaymentsToBeReceivedFourYears_637713934743013107" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_LessorOperatingLeasePaymentsToBeReceived" xlink:to="us-gaap_LessorOperatingLeasePaymentsToBeReceivedFourYears_637713934743013107" order="5" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="adc-20210930.xsd#adc_LessorOperatingLeasePaymentToBeReceivedYearFiveAndAfterYearFive" xlink:label="adc_LessorOperatingLeasePaymentToBeReceivedYearFiveAndAfterYearFive_637713934743013107" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_LessorOperatingLeasePaymentsToBeReceived" xlink:to="adc_LessorOperatingLeasePaymentToBeReceivedYearFiveAndAfterYearFive_637713934743013107" order="6" use="optional" weight="1" priority="1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingLeaseLeaseIncome" xlink:label="us-gaap_OperatingLeaseLeaseIncome" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingLeaseLeaseIncomeLeasePayments" xlink:label="us-gaap_OperatingLeaseLeaseIncomeLeasePayments_637713934743013107" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_OperatingLeaseLeaseIncome" xlink:to="us-gaap_OperatingLeaseLeaseIncomeLeasePayments_637713934743013107" order="1" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingLeaseVariableLeaseIncome" xlink:label="us-gaap_OperatingLeaseVariableLeaseIncome_637713934743013107" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_OperatingLeaseLeaseIncome" xlink:to="us-gaap_OperatingLeaseVariableLeaseIncome_637713934743013107" order="2" use="optional" weight="1" priority="2" />
  </calculationLink>
  <calculationLink xlink:role="http://www.agreerealty.com/role/DisclosureLeasesLandLeaseObligationsDetails" xlink:type="extended" xlink:title="40303 - Disclosure - Leases - Land Lease Obligations (Details)">
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FinanceLeaseLiability" xlink:label="us-gaap_FinanceLeaseLiability" />
    <loc xlink:type="locator" xlink:href="adc-20210930.xsd#adc_NetFinanceLeaseLiabilityPaymentsNextTwelveMonths" xlink:label="adc_NetFinanceLeaseLiabilityPaymentsNextTwelveMonths_637713934743023107" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_FinanceLeaseLiability" xlink:to="adc_NetFinanceLeaseLiabilityPaymentsNextTwelveMonths_637713934743023107" order="1" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="adc-20210930.xsd#adc_NetFinanceLeaseLiabilityPaymentsRemainderOfFiscalYear" xlink:label="adc_NetFinanceLeaseLiabilityPaymentsRemainderOfFiscalYear_637713934743023107" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_FinanceLeaseLiability" xlink:to="adc_NetFinanceLeaseLiabilityPaymentsRemainderOfFiscalYear_637713934743023107" order="2" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="adc-20210930.xsd#adc_NetFinanceLeaseLiabilityPaymentsYearFiveAndAfterYearFive" xlink:label="adc_NetFinanceLeaseLiabilityPaymentsYearFiveAndAfterYearFive_637713934743023107" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_FinanceLeaseLiability" xlink:to="adc_NetFinanceLeaseLiabilityPaymentsYearFiveAndAfterYearFive_637713934743023107" order="3" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="adc-20210930.xsd#adc_NetFinanceLeaseLiabilityPaymentsYearFour" xlink:label="adc_NetFinanceLeaseLiabilityPaymentsYearFour_637713934743023107" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_FinanceLeaseLiability" xlink:to="adc_NetFinanceLeaseLiabilityPaymentsYearFour_637713934743023107" order="4" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="adc-20210930.xsd#adc_NetFinanceLeaseLiabilityPaymentsYearThree" xlink:label="adc_NetFinanceLeaseLiabilityPaymentsYearThree_637713934743023107" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_FinanceLeaseLiability" xlink:to="adc_NetFinanceLeaseLiabilityPaymentsYearThree_637713934743023107" order="5" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="adc-20210930.xsd#adc_NetFinanceLeaseLiabilityPaymentsYearTwo" xlink:label="adc_NetFinanceLeaseLiabilityPaymentsYearTwo_637713934743023107" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_FinanceLeaseLiability" xlink:to="adc_NetFinanceLeaseLiabilityPaymentsYearTwo_637713934743023107" order="6" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FinanceLeaseLiabilityPaymentsDue" xlink:label="us-gaap_FinanceLeaseLiabilityPaymentsDue" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FinanceLeaseLiabilityPaymentsRemainderOfFiscalYear" xlink:label="us-gaap_FinanceLeaseLiabilityPaymentsRemainderOfFiscalYear_637713934743023107" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_FinanceLeaseLiabilityPaymentsDue" xlink:to="us-gaap_FinanceLeaseLiabilityPaymentsRemainderOfFiscalYear_637713934743023107" order="1" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FinanceLeaseLiabilityPaymentsDueYearFour" xlink:label="us-gaap_FinanceLeaseLiabilityPaymentsDueYearFour_637713934743033178" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_FinanceLeaseLiabilityPaymentsDue" xlink:to="us-gaap_FinanceLeaseLiabilityPaymentsDueYearFour_637713934743033178" order="2" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FinanceLeaseLiabilityPaymentsDueNextTwelveMonths" xlink:label="us-gaap_FinanceLeaseLiabilityPaymentsDueNextTwelveMonths_637713934743033178" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_FinanceLeaseLiabilityPaymentsDue" xlink:to="us-gaap_FinanceLeaseLiabilityPaymentsDueNextTwelveMonths_637713934743033178" order="3" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FinanceLeaseLiabilityPaymentsDueYearThree" xlink:label="us-gaap_FinanceLeaseLiabilityPaymentsDueYearThree_637713934743033178" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_FinanceLeaseLiabilityPaymentsDue" xlink:to="us-gaap_FinanceLeaseLiabilityPaymentsDueYearThree_637713934743033178" order="4" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FinanceLeaseLiabilityPaymentsDueYearTwo" xlink:label="us-gaap_FinanceLeaseLiabilityPaymentsDueYearTwo_637713934743033178" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_FinanceLeaseLiabilityPaymentsDue" xlink:to="us-gaap_FinanceLeaseLiabilityPaymentsDueYearTwo_637713934743033178" order="5" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="adc-20210930.xsd#adc_FinanceLeasesLiabilityUndiscountedExcessAmount" xlink:label="adc_FinanceLeasesLiabilityUndiscountedExcessAmount" />
    <loc xlink:type="locator" xlink:href="adc-20210930.xsd#adc_FinanceLeaseLiabilityUndiscountedExcessAmountNextTwelveMonths" xlink:label="adc_FinanceLeaseLiabilityUndiscountedExcessAmountNextTwelveMonths_637713934743033178" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="adc_FinanceLeasesLiabilityUndiscountedExcessAmount" xlink:to="adc_FinanceLeaseLiabilityUndiscountedExcessAmountNextTwelveMonths_637713934743033178" order="1" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="adc-20210930.xsd#adc_FinanceLeaseLiabilityUndiscountedExcessAmountRemainderOfFiscalYear" xlink:label="adc_FinanceLeaseLiabilityUndiscountedExcessAmountRemainderOfFiscalYear_637713934743033178" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="adc_FinanceLeasesLiabilityUndiscountedExcessAmount" xlink:to="adc_FinanceLeaseLiabilityUndiscountedExcessAmountRemainderOfFiscalYear_637713934743033178" order="2" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="adc-20210930.xsd#adc_FinanceLeaseLiabilityUndiscountedExcessAmountYearFiveAndAfterYearFive" xlink:label="adc_FinanceLeaseLiabilityUndiscountedExcessAmountYearFiveAndAfterYearFive_637713934743043105" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="adc_FinanceLeasesLiabilityUndiscountedExcessAmount" xlink:to="adc_FinanceLeaseLiabilityUndiscountedExcessAmountYearFiveAndAfterYearFive_637713934743043105" order="3" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="adc-20210930.xsd#adc_FinanceLeaseLiabilityUndiscountedExcessAmountYearFour" xlink:label="adc_FinanceLeaseLiabilityUndiscountedExcessAmountYearFour_637713934743043105" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="adc_FinanceLeasesLiabilityUndiscountedExcessAmount" xlink:to="adc_FinanceLeaseLiabilityUndiscountedExcessAmountYearFour_637713934743043105" order="4" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="adc-20210930.xsd#adc_FinanceLeaseLiabilityUndiscountedExcessAmountYearThree" xlink:label="adc_FinanceLeaseLiabilityUndiscountedExcessAmountYearThree_637713934743043105" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="adc_FinanceLeasesLiabilityUndiscountedExcessAmount" xlink:to="adc_FinanceLeaseLiabilityUndiscountedExcessAmountYearThree_637713934743043105" order="5" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="adc-20210930.xsd#adc_FinanceLeaseLiabilityUndiscountedExcessAmountYearTwo" xlink:label="adc_FinanceLeaseLiabilityUndiscountedExcessAmountYearTwo_637713934743043105" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="adc_FinanceLeasesLiabilityUndiscountedExcessAmount" xlink:to="adc_FinanceLeaseLiabilityUndiscountedExcessAmountYearTwo_637713934743043105" order="6" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue" xlink:label="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue" />
    <loc xlink:type="locator" xlink:href="adc-20210930.xsd#adc_LesseeOperatingLeaseLiabilityToBePaidYearFiveAndAfterYearFive" xlink:label="adc_LesseeOperatingLeaseLiabilityToBePaidYearFiveAndAfterYearFive_637713934743043105" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue" xlink:to="adc_LesseeOperatingLeaseLiabilityToBePaidYearFiveAndAfterYearFive_637713934743043105" order="1" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear" xlink:label="us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear_637713934743043105" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue" xlink:to="us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear_637713934743043105" order="2" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths" xlink:label="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths_637713934743053109" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue" xlink:to="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths_637713934743053109" order="3" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour" xlink:label="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour_637713934743053109" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue" xlink:to="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour_637713934743053109" order="4" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree" xlink:label="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree_637713934743053109" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue" xlink:to="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree_637713934743053109" order="5" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo" xlink:label="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo_637713934743053109" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue" xlink:to="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo_637713934743053109" order="6" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount" xlink:label="us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount" />
    <loc xlink:type="locator" xlink:href="adc-20210930.xsd#adc_LesseeOperatingLeaseLiabilityUndiscountedExcessAmountNextTwelveMonths" xlink:label="adc_LesseeOperatingLeaseLiabilityUndiscountedExcessAmountNextTwelveMonths_637713934743053109" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount" xlink:to="adc_LesseeOperatingLeaseLiabilityUndiscountedExcessAmountNextTwelveMonths_637713934743053109" order="1" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="adc-20210930.xsd#adc_LesseeOperatingLeaseLiabilityUndiscountedExcessAmountRemainderOfFiscalYear" xlink:label="adc_LesseeOperatingLeaseLiabilityUndiscountedExcessAmountRemainderOfFiscalYear_637713934743063104" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount" xlink:to="adc_LesseeOperatingLeaseLiabilityUndiscountedExcessAmountRemainderOfFiscalYear_637713934743063104" order="2" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="adc-20210930.xsd#adc_LesseeOperatingLeaseLiabilityUndiscountedExcessAmountYearFiveAndAfterYearFive" xlink:label="adc_LesseeOperatingLeaseLiabilityUndiscountedExcessAmountYearFiveAndAfterYearFive_637713934743063104" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount" xlink:to="adc_LesseeOperatingLeaseLiabilityUndiscountedExcessAmountYearFiveAndAfterYearFive_637713934743063104" order="3" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="adc-20210930.xsd#adc_LesseeOperatingLeaseLiabilityUndiscountedExcessAmountYearFour" xlink:label="adc_LesseeOperatingLeaseLiabilityUndiscountedExcessAmountYearFour_637713934743063104" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount" xlink:to="adc_LesseeOperatingLeaseLiabilityUndiscountedExcessAmountYearFour_637713934743063104" order="4" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="adc-20210930.xsd#adc_LesseeOperatingLeaseLiabilityUndiscountedExcessAmountYearThree" xlink:label="adc_LesseeOperatingLeaseLiabilityUndiscountedExcessAmountYearThree_637713934743063104" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount" xlink:to="adc_LesseeOperatingLeaseLiabilityUndiscountedExcessAmountYearThree_637713934743063104" order="5" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="adc-20210930.xsd#adc_LesseeOperatingLeaseLiabilityUndiscountedExcessAmountYearTwo" xlink:label="adc_LesseeOperatingLeaseLiabilityUndiscountedExcessAmountYearTwo_637713934743063104" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount" xlink:to="adc_LesseeOperatingLeaseLiabilityUndiscountedExcessAmountYearTwo_637713934743063104" order="6" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingLeaseLiability" xlink:label="us-gaap_OperatingLeaseLiability" />
    <loc xlink:type="locator" xlink:href="adc-20210930.xsd#adc_NetLesseeOperatingLeaseLiabilityPaymentsNextTwelveMonths" xlink:label="adc_NetLesseeOperatingLeaseLiabilityPaymentsNextTwelveMonths_637713934743073102" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_OperatingLeaseLiability" xlink:to="adc_NetLesseeOperatingLeaseLiabilityPaymentsNextTwelveMonths_637713934743073102" order="1" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="adc-20210930.xsd#adc_NetLesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear" xlink:label="adc_NetLesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear_637713934743073102" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_OperatingLeaseLiability" xlink:to="adc_NetLesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear_637713934743073102" order="2" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="adc-20210930.xsd#adc_NetLesseeOperatingLeaseLiabilityPaymentsYearFiveAndAfterYearFive" xlink:label="adc_NetLesseeOperatingLeaseLiabilityPaymentsYearFiveAndAfterYearFive_637713934743073102" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_OperatingLeaseLiability" xlink:to="adc_NetLesseeOperatingLeaseLiabilityPaymentsYearFiveAndAfterYearFive_637713934743073102" order="3" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="adc-20210930.xsd#adc_NetLesseeOperatingLeaseLiabilityPaymentsYearFour" xlink:label="adc_NetLesseeOperatingLeaseLiabilityPaymentsYearFour_637713934743073102" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_OperatingLeaseLiability" xlink:to="adc_NetLesseeOperatingLeaseLiabilityPaymentsYearFour_637713934743073102" order="4" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="adc-20210930.xsd#adc_NetLesseeOperatingLeaseLiabilityPaymentsYearThree" xlink:label="adc_NetLesseeOperatingLeaseLiabilityPaymentsYearThree_637713934743073102" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_OperatingLeaseLiability" xlink:to="adc_NetLesseeOperatingLeaseLiabilityPaymentsYearThree_637713934743073102" order="5" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="adc-20210930.xsd#adc_NetLesseeOperatingLeaseLiabilityPaymentsYearTwo" xlink:label="adc_NetLesseeOperatingLeaseLiabilityPaymentsYearTwo_637713934743083102" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_OperatingLeaseLiability" xlink:to="adc_NetLesseeOperatingLeaseLiabilityPaymentsYearTwo_637713934743083102" order="6" use="optional" weight="1" priority="2" />
  </calculationLink>
  <calculationLink xlink:role="http://www.agreerealty.com/role/DisclosureLeasesLandLeaseObligationsDetailsCalc2" xlink:type="extended" xlink:title="40303 - Disclosure - Leases - Land Lease Obligations (Details) (Calc 2)">
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue" xlink:label="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount" xlink:label="us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount_637713934743083102" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue" xlink:to="us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount_637713934743083102" order="1" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingLeaseLiability" xlink:label="us-gaap_OperatingLeaseLiability_637713934743083102" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue" xlink:to="us-gaap_OperatingLeaseLiability_637713934743083102" order="2" use="optional" weight="1" priority="2" />
  </calculationLink>
  <calculationLink xlink:role="http://www.agreerealty.com/role/DisclosureDebtMortgagesPayableDetails" xlink:type="extended" xlink:title="40502 - Disclosure - Debt - Mortgages Payable (Details)">
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongTermDebt" xlink:label="us-gaap_LongTermDebt" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DeferredFinanceCostsNet" xlink:label="us-gaap_DeferredFinanceCostsNet_637713934743093178" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_LongTermDebt" xlink:to="us-gaap_DeferredFinanceCostsNet_637713934743093178" order="1" use="optional" weight="-1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentCarryingAmount" xlink:label="us-gaap_DebtInstrumentCarryingAmount_637713934743093178" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_LongTermDebt" xlink:to="us-gaap_DebtInstrumentCarryingAmount_637713934743093178" order="2" use="optional" weight="1" priority="2" />
  </calculationLink>
  <calculationLink xlink:role="http://www.agreerealty.com/role/DisclosureDebtSeniorUnsecuredNotesDetails" xlink:type="extended" xlink:title="40504 - Disclosure - Debt - Senior Unsecured Notes (Details)">
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongTermDebt" xlink:label="us-gaap_LongTermDebt" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet" xlink:label="us-gaap_DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet_637713934743093178" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_LongTermDebt" xlink:to="us-gaap_DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet_637713934743093178" order="1" use="optional" weight="-1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentCarryingAmount" xlink:label="us-gaap_DebtInstrumentCarryingAmount_637713934743093178" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_LongTermDebt" xlink:to="us-gaap_DebtInstrumentCarryingAmount_637713934743093178" order="2" use="optional" weight="1" priority="2" />
  </calculationLink>
  <calculationLink xlink:role="http://www.agreerealty.com/role/DisclosureDebtDebtMaturitiesDetails" xlink:type="extended" xlink:title="40505 - Disclosure - Debt - Debt Maturities (Details)">
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongTermDebt" xlink:label="us-gaap_LongTermDebt" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentCarryingAmount" xlink:label="us-gaap_DebtInstrumentCarryingAmount_637713934743093178" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_LongTermDebt" xlink:to="us-gaap_DebtInstrumentCarryingAmount_637713934743093178" order="1" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalRemainderOfFiscalYear" xlink:label="us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalRemainderOfFiscalYear_637713934743103107" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_DebtInstrumentCarryingAmount_637713934743093178" xlink:to="us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalRemainderOfFiscalYear_637713934743103107" order="1" use="optional" weight="1" priority="1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearTwo" xlink:label="us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearTwo_637713934743103107" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_DebtInstrumentCarryingAmount_637713934743093178" xlink:to="us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearTwo_637713934743103107" order="2" use="optional" weight="1" priority="1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearThree" xlink:label="us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearThree_637713934743103107" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_DebtInstrumentCarryingAmount_637713934743093178" xlink:to="us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearThree_637713934743103107" order="3" use="optional" weight="1" priority="1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFour" xlink:label="us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFour_637713934743103107" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_DebtInstrumentCarryingAmount_637713934743093178" xlink:to="us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFour_637713934743103107" order="4" use="optional" weight="1" priority="1" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInNextTwelveMonths" xlink:label="us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInNextTwelveMonths_637713934743103107" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_DebtInstrumentCarryingAmount_637713934743093178" xlink:to="us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInNextTwelveMonths_637713934743103107" order="5" use="optional" weight="1" priority="3" />
    <loc xlink:type="locator" xlink:href="adc-20210930.xsd#adc_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFiveAndAfterYearFive" xlink:label="adc_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFiveAndAfterYearFive_637713934743103107" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_DebtInstrumentCarryingAmount_637713934743093178" xlink:to="adc_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFiveAndAfterYearFive_637713934743103107" order="6" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentUnamortizedDiscount" xlink:label="us-gaap_DebtInstrumentUnamortizedDiscount_637713934743103107" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_LongTermDebt" xlink:to="us-gaap_DebtInstrumentUnamortizedDiscount_637713934743103107" order="2" use="optional" weight="-1" priority="4" />
  </calculationLink>
  <calculationLink xlink:role="http://www.agreerealty.com/role/DisclosureDerivativeInstrumentsAndHedgingActivityOffsettingOfDerivativeAssetsAndLiabilitiesDetails" xlink:type="extended" xlink:title="40905 - Disclosure - Derivative Instruments and Hedging Activity - Offsetting of Derivative Assets and Liabilities (Details)">
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeAssetFairValueOffsetAgainstCollateralNetOfNotSubjectToMasterNettingArrangementPolicyElection" xlink:label="us-gaap_DerivativeAssetFairValueOffsetAgainstCollateralNetOfNotSubjectToMasterNettingArrangementPolicyElection" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeAssets" xlink:label="us-gaap_DerivativeAssets_637713934743103107" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_DerivativeAssetFairValueOffsetAgainstCollateralNetOfNotSubjectToMasterNettingArrangementPolicyElection" xlink:to="us-gaap_DerivativeAssets_637713934743103107" order="1" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeFairValueOfDerivativeAsset" xlink:label="us-gaap_DerivativeFairValueOfDerivativeAsset_637713934743113103" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_DerivativeAssets_637713934743103107" xlink:to="us-gaap_DerivativeFairValueOfDerivativeAsset_637713934743113103" order="1" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeAssetFairValueGrossLiability" xlink:label="us-gaap_DerivativeAssetFairValueGrossLiability_637713934743113103" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_DerivativeAssets_637713934743103107" xlink:to="us-gaap_DerivativeAssetFairValueGrossLiability_637713934743113103" order="2" use="optional" weight="-1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeAssetNotOffsetPolicyElectionDeduction" xlink:label="us-gaap_DerivativeAssetNotOffsetPolicyElectionDeduction_637713934743113103" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_DerivativeAssetFairValueOffsetAgainstCollateralNetOfNotSubjectToMasterNettingArrangementPolicyElection" xlink:to="us-gaap_DerivativeAssetNotOffsetPolicyElectionDeduction_637713934743113103" order="2" use="optional" weight="-1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeCollateralObligationToReturnCash" xlink:label="us-gaap_DerivativeCollateralObligationToReturnCash_637713934743113103" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_DerivativeAssetFairValueOffsetAgainstCollateralNetOfNotSubjectToMasterNettingArrangementPolicyElection" xlink:to="us-gaap_DerivativeCollateralObligationToReturnCash_637713934743113103" order="3" use="optional" weight="-1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeLiabilityFairValueOffsetAgainstCollateralNetOfNotSubjectToMasterNettingArrangementPolicyElection" xlink:label="us-gaap_DerivativeLiabilityFairValueOffsetAgainstCollateralNetOfNotSubjectToMasterNettingArrangementPolicyElection" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeLiabilities" xlink:label="us-gaap_DerivativeLiabilities_637713934743113103" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_DerivativeLiabilityFairValueOffsetAgainstCollateralNetOfNotSubjectToMasterNettingArrangementPolicyElection" xlink:to="us-gaap_DerivativeLiabilities_637713934743113103" order="1" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeLiabilityFairValueGrossAsset" xlink:label="us-gaap_DerivativeLiabilityFairValueGrossAsset_637713934743113103" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_DerivativeLiabilities_637713934743113103" xlink:to="us-gaap_DerivativeLiabilityFairValueGrossAsset_637713934743113103" order="1" use="optional" weight="-1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeFairValueOfDerivativeLiability" xlink:label="us-gaap_DerivativeFairValueOfDerivativeLiability_637713934743113103" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_DerivativeLiabilities_637713934743113103" xlink:to="us-gaap_DerivativeFairValueOfDerivativeLiability_637713934743113103" order="2" use="optional" weight="1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeLiabilityNotOffsetPolicyElectionDeduction" xlink:label="us-gaap_DerivativeLiabilityNotOffsetPolicyElectionDeduction_637713934743123103" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_DerivativeLiabilityFairValueOffsetAgainstCollateralNetOfNotSubjectToMasterNettingArrangementPolicyElection" xlink:to="us-gaap_DerivativeLiabilityNotOffsetPolicyElectionDeduction_637713934743123103" order="2" use="optional" weight="-1" priority="2" />
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeCollateralRightToReclaimCash" xlink:label="us-gaap_DerivativeCollateralRightToReclaimCash_637713934743123103" />
    <calculationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="us-gaap_DerivativeLiabilityFairValueOffsetAgainstCollateralNetOfNotSubjectToMasterNettingArrangementPolicyElection" xlink:to="us-gaap_DerivativeCollateralRightToReclaimCash_637713934743123103" order="3" use="optional" weight="-1" priority="2" />
  </calculationLink>
</link:linkbase>
