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v3.25.1

CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands | 3 Months Ended
--- | ---
Mar. 31, 2025 | Mar. 31, 2024
Operating activities |  |
Net loss | $ (92,541) | $ (14,618)
Adjustments to reconcile net loss to net cash provided by operating activities: |  |
Intangible asset amortization | 154,448 | 155,730
Share-based compensation | 67,653 | 61,441
Acquisition accounting inventory fair value step-up adjustment | 29,880 | 28,943
Non-cash interest expense | 17,066 | 5,988
Depreciation | 10,425 | 7,653
Provision for losses on accounts receivable and inventory | 5,319 | 7,403
Acquired in-process research and development | 0 | 10,000
Deferred tax benefit | (43,833) | (66,385)
Other non-cash transactions | (6,537) | 14,674
Changes in assets and liabilities: |  |
Accounts receivable | 66,049 | (8,443)
Inventories | (35,621) | (12,844)
Prepaid expenses and other current assets | 36,277 | 54,947
Operating lease assets | 5,913 | 3,703
Other non-current assets | (752) | (4,090)
Accounts payable | 19,131 | (19,597)
Accrued liabilities | 181,038 | 34,677
Income taxes payable | 12,988 | 14,858
Operating lease liabilities, less current portion | (1,090) | (2,980)
Other non-current liabilities | 3,971 | (3,831)
Net cash provided by operating activities | 429,784 | 267,229
Investing activities |  |
Acquisition of investments | (440,050) | (375,000)
Acquisition of intangible assets | (25,000) | 0
Purchases of property, plant and equipment | (13,881) | (6,904)
Proceeds from maturity of investments | 310,000 | 120,000
Acquired in-process research and development | 0 | (10,000)
Net cash used in investing activities | (168,931) | (271,904)
Financing activities |  |
Repayments of long-term debt | (757,750) | (7,750)
Payment of employee withholding taxes related to share-based awards | (67,163) | (49,296)
Proceeds from employee equity incentive and purchase plans | 11,447 | 494
Net cash used in financing activities | (813,466) | (56,552)
Effect of exchange rates on cash and cash equivalents | 1,695 | (1,698)
Net decrease in cash and cash equivalents | (550,918) | (62,925)
Cash and cash equivalents, at beginning of period | 2,412,864 | 1,506,310
Cash and cash equivalents, at end of period | $ 1,861,946 | $ 1,443,385

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