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Certain Balance Sheet Items | 3 Months Ended
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Mar. 31, 2025
Certain Balance Sheet Items [Abstract] |
Certain Balance Sheet Items | Certain Balance Sheet Items Property, plant and equipment consisted of the following (in thousands):
| March 31, 2025 |  | December 31, 2024
Manufacturing equipment and machinery | $ | 90,767 |  |  | $ | 87,451 |
Land and buildings | 72,502 |  |  | 71,902 |
Leasehold improvements | 70,489 |  |  | 70,201 |
Computer software | 44,914 |  |  | 42,635 |
Construction-in-progress | 43,078 |  |  | 34,493 |
Computer equipment | 20,113 |  |  | 20,137 |
Furniture and fixtures | 8,570 |  |  | 8,551 |
Subtotal | 350,433 |  |  | 335,370 |
Less accumulated depreciation and amortization | (171,564) |  |  | (161,957) |
Property, plant and equipment, net | $ | 178,869 |  |  | $ | 173,413 |
Accrued liabilities consisted of the following (in thousands):
| March 31, 2025 |  | December 31, 2024
Rebates and other sales deductions | $ | 442,765 |  |  | $ | 342,717 |
Accrued litigation settlement expenses | 172,000 |  |  | — |
Employee compensation and benefits | 139,388 |  |  | 153,133 |
Clinical trial accruals | 32,700 |  |  | 49,962 |
Consulting and professional services | 32,279 |  |  | 26,221 |
Accrued royalties | 29,270 |  |  | 36,802 |
Sales return reserve | 28,132 |  |  | 26,428 |
Inventory-related accruals | 27,396 |  |  | 25,509 |
Accrued development expenses | 26,295 |  |  | 23,099 |
Selling and marketing accruals | 22,532 |  |  | 26,981 |
Accrued interest | 21,485 |  |  | 41,626 |
Current portion of lease liabilities | 13,444 |  |  | 14,779 |
Accrued construction-in-progress | 9,377 |  |  | 10,061 |
Accrued collaboration expenses | 6,485 |  |  | 18,005 |
Accrued milestones | — |  |  | 27,500 |
Derivative instrument liabilities | — |  |  | 10,198 |
Other | 60,370 |  |  | 77,926 |
Total accrued liabilities | $ | 1,063,918 |  |  | $ | 910,947 |

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- Definition Certain Balance Sheet Items [Abstract] + References No definition available. + Details
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- Definition The entire disclosure for supplemental balance sheet disclosures, including descriptions and amounts for assets, liabilities, and equity. + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 210 -Name Accounting Standards Codification -Publisher FASB -URI https://asc.fasb.org/210/tableOfContent + Details
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