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Segment and Geographic Information
 12 Months Ended
Dec. 31, 2024
Segment Reporting [Abstract]  
Segment and Geographic Information Segment and Geographic Information
The Company operates as one operating segment, and the Company's chief operating decision makers, or the CODMs, are its Co-Chief Executive Officers. The CODMs review segment financial information presented on a consolidated basis, including revenue, gross profit, operating expenses, net loss and adjusted EBITDA, and considers budget-to-actual variances for the purposes of making operating decisions, assessing financial performance and allocating resources. The CODMs do not evaluate operating segment performance using asset information.
The following table presents a summary of the Company's segment information:
Year Ended December 31,
202420232022
(in thousands)
Revenue$739,016 $563,948 $449,538 
Less:
Cost of precision oncology testing (1)
254,551 200,202 141,691 
Cost of development services and other (1)
24,886 18,863 8,126 
Research and development expense (1)
295,866 329,826 341,650 
Sales and marketing expense (1)
328,064 270,132 273,961 
General and administrative expense (1)
133,352 129,247 121,023 
Other segment items (2)
138,670 95,127 217,675 
Net loss$(436,373)$(479,449)$(654,588)
(1)Excludes stock-based compensation and related employer payroll tax payments, contingent consideration, and amortization of intangible assets.
(2)Includes stock-based compensation and related employer payroll tax payments, contingent consideration, amortization of intangible assets, interest income and expense, provision for income taxes, and other income and expense.
The following table sets forth the Company’s revenue by geographic areas based on the customers’ locations:
Year Ended December 31,
202420232022
(in thousands)
United States $697,162 $526,524 $420,618 
International41,854 37,424 28,920 
Total revenue
$739,016 $563,948 $449,538 
As of December 31, 2024 and 2023, 99% and 98%, respectively, of the Company’s long-lived assets and right-of-use assets are located in the United States.