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Consolidated Statements of Stockholders’ Equity (Deficit) - USD ($)
$ in Thousands
Total
Common Stock 
Additional Paid-in Capital
Accumulated Other Comprehensive Loss
  Accumulated Deficit
Beginning balance (in shares) at Dec. 31, 2021   101,767,446      
Beginning balance at Dec. 31, 2021 $ 645,005 $ 1 $ 1,657,593 $ (4,764) $ (1,007,825)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Issuance of common stock upon exercise of stock options (in shares) 228,311 228,311      
Issuance of common stock upon exercise of stock options $ 2,625   2,625    
Vesting of restricted stock units (in shares)   315,673      
Vesting of common stock exercised early 8   8    
Issuance of common stock under employee stock purchase plan (in shares)   307,953      
Issuance of common stock under employee stock purchase plan 9,316   9,316    
Employee taxes paid related to settlement of restricted stock units (7,878)   (7,878)    
Stock-based compensation 94,685   94,685    
Tender offer issued in connection with the Joint Venture Acquisition and acquisition related costs (14,235)   (14,235)    
Other comprehensive (loss) income (14,758)     (14,758)  
Net loss (654,588)       (654,588)
Ending balance (in shares) at Dec. 31, 2022   102,619,383      
Ending balance at Dec. 31, 2022 60,180 $ 1 1,742,114 (19,522) (1,662,413)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Issuance of common stock upon follow-on offering, net of offering costs (in shares)   14,375,000      
Issuance of common stock upon follow-on offering, net of offering costs 381,369   381,369    
Issuance of common stock upon registered direct offering (in shares)   3,387,446      
Issuance of common stock upon registered direct offering $ 90,616   90,616    
Issuance of common stock upon exercise of stock options (in shares) 51,124 51,124      
Issuance of common stock upon exercise of stock options $ 405   405    
Vesting of restricted stock units (in shares)   732,038      
Issuance of common stock under employee stock purchase plan (in shares)   464,870      
Issuance of common stock under employee stock purchase plan 10,154   10,154    
Employee taxes paid related to settlement of restricted stock units (11,197)   (11,197)    
Stock-based compensation 90,759   90,759    
Other comprehensive (loss) income 15,847     15,847  
Net loss (479,449)       (479,449)
Ending balance (in shares) at Dec. 31, 2023   121,629,861      
Ending balance at Dec. 31, 2023 $ 158,684 $ 1 2,304,220 (3,675) (2,141,862)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Issuance of common stock upon exercise of stock options (in shares) 609,495 609,495      
Issuance of common stock upon exercise of stock options $ 3,119   3,119    
Vesting of restricted stock units (in shares)   1,176,892      
Issuance of common stock under employee stock purchase plan (in shares)   577,758      
Issuance of common stock under employee stock purchase plan 11,719   11,719    
Employee taxes paid related to settlement of restricted stock units (15,681)   (15,681)    
Stock-based compensation 140,411   140,411    
Other comprehensive (loss) income (1,526)     (1,526)  
Net loss (436,373)       (436,373)
Ending balance (in shares) at Dec. 31, 2024   123,994,006      
Ending balance at Dec. 31, 2024 $ (139,647) $ 1 $ 2,443,788 $ (5,201) $ (2,578,235)