    <SEC-DOCUMENT>0001193125-25-103939-index.html : 20250429
    <SEC-HEADER>0001193125-25-103939.hdr.sgml : 20250429
    <ACCEPTANCE-DATETIME>20250429163713
    ACCESSION NUMBER:		0001193125-25-103939
    CONFORMED SUBMISSION TYPE:	ARS
    PUBLIC DOCUMENT COUNT:		1
    CONFORMED PERIOD OF REPORT:	20241231
    FILED AS OF DATE:		20250429
    DATE AS OF CHANGE:		20250429
    EFFECTIVENESS DATE:		20250429

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			Guardant Health, Inc.
    		CENTRAL INDEX KEY:			0001576280
    		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-MEDICAL LABORATORIES [8071]
    		ORGANIZATION NAME:           	08 Industrial Applications and Services
    		EIN:				454139254
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		ARS
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-38683
    		FILM NUMBER:		25888428

    	BUSINESS ADDRESS:
    		STREET 1:		3100 HANOVER STREET
    		CITY:			PALO ALTO
    		STATE:			CA
    		ZIP:			94304
    		BUSINESS PHONE:		855-698-8887

    	MAIL ADDRESS:
    		STREET 1:		3100 HANOVER STREET
    		CITY:			PALO ALTO
    		STATE:			CA
    		ZIP:			94304
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>ARS
    <SEQUENCE>1
    <FILENAME>d831399dars.pdf
    <DESCRIPTION>ARS
    <TEXT>
    Document 1 - file: d831399dars.pdf

    </DOCUMENT>
    </SEC-DOCUMENT>