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Common Stock - Stock by Class (Details) - shares
Sep. 30, 2025
Dec. 31, 2024
Class of Stock [Line Items]    
Common stock, shares reserved for future issuance (in shares) 29,955,166 27,147,526
Shares underlying outstanding stock options    
Class of Stock [Line Items]    
Common stock, shares reserved for future issuance (in shares) 4,987,566 4,631,750
Shares underlying unvested restricted stock units    
Class of Stock [Line Items]    
Common stock, shares reserved for future issuance (in shares) 7,558,342 7,020,251
Performance-based restricted stock units granted    
Class of Stock [Line Items]    
Common stock, shares reserved for future issuance (in shares) 1,268,235 1,290,684
Shares available for issuance under the 2018 Incentive Award Plan    
Class of Stock [Line Items]    
Common stock, shares reserved for future issuance (in shares) 9,659,638 8,079,498
Shares available for issuance under the 2018 Employee Stock Purchase Plan    
Class of Stock [Line Items]    
Common stock, shares reserved for future issuance (in shares) 3,004,890 2,208,577
Shares available for issuance under the 2023 Employment Inducement Incentive Award Plan    
Class of Stock [Line Items]    
Common stock, shares reserved for future issuance (in shares) 3,476,495 3,916,766