<SEC-DOCUMENT>0001576280-25-000062.txt : 20250304
<SEC-HEADER>0001576280-25-000062.hdr.sgml : 20250304
<ACCEPTANCE-DATETIME>20250304181628
ACCESSION NUMBER:		0001576280-25-000062
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20250301
FILED AS OF DATE:		20250304
DATE AS OF CHANGE:		20250304

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Saia John G.
		CENTRAL INDEX KEY:			0001737840
		ORGANIZATION NAME:           	

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-38683
		FILM NUMBER:		25707226

	MAIL ADDRESS:	
		STREET 1:		3100 HANOVER STREET
		CITY:			PALO ALTO
		STATE:			CA
		ZIP:			94304

	FORMER NAME:	
		FORMER CONFORMED NAME:	Saia John
		DATE OF NAME CHANGE:	20180417

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Guardant Health, Inc.
		CENTRAL INDEX KEY:			0001576280
		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-MEDICAL LABORATORIES [8071]
		ORGANIZATION NAME:           	08 Industrial Applications and Services
		IRS NUMBER:				454139254
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		3100 HANOVER STREET
		CITY:			PALO ALTO
		STATE:			CA
		ZIP:			94304
		BUSINESS PHONE:		855-698-8887

	MAIL ADDRESS:	
		STREET 1:		3100 HANOVER STREET
		CITY:			PALO ALTO
		STATE:			CA
		ZIP:			94304
</SEC-HEADER>
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<SEQUENCE>1
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<DESCRIPTION>FORM 4
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    <issuer>
        <issuerCik>0001576280</issuerCik>
        <issuerName>Guardant Health, Inc.</issuerName>
        <issuerTradingSymbol>GH</issuerTradingSymbol>
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            <rptOwnerStreet1>3100 HANOVER STREET</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>PALO ALTO</rptOwnerCity>
            <rptOwnerState>CA</rptOwnerState>
            <rptOwnerZipCode>94304</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
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            <isDirector>0</isDirector>
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            <isTenPercentOwner>0</isTenPercentOwner>
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            <officerTitle>Chief Legal Officer</officerTitle>
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    <footnotes>
        <footnote id="F1">These shares were retained by the Company in order to meet the tax withholding obligations of the award-holder in connection with the vesting of an installment of the restricted stock units. The amount retained by the Company was not in excess of the amount of the tax liability.</footnote>
        <footnote id="F2">This represents a performance-based restricted stock unit award granted on February 26, 2024, that a performance metric was achieved and that 33% of the shares subject to such award vested on March 1, 2025. The remaining 67% of the shares vest over the following two years, with 33% of the shares subject to the award vesting on January 1, 2026, and 34% of the shares subject to the award vesting on January 1, 2027.</footnote>
        <footnote id="F3">Not applicable for Restricted Stock Units.</footnote>
        <footnote id="F4">The restricted stock unit award  was granted on November 2, 2021, and vested as to 25% of the shares subject to such award on September 1, 2022,  the remaining 75% of the shares subject to such award vest in equal installments on each quarterly anniversary of September 1, 2022 during the three-year period thereafter.</footnote>
    </footnotes>

    <remarks></remarks>

    <ownerSignature>
        <signatureName>/s/ John G. Saia</signatureName>
        <signatureDate>2025-03-04</signatureDate>
    </ownerSignature>
</ownershipDocument>
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</SEC-DOCUMENT>
