<SEC-DOCUMENT>0001576280-25-000213.txt : 20250702
<SEC-HEADER>0001576280-25-000213.hdr.sgml : 20250702
<ACCEPTANCE-DATETIME>20250702211851
ACCESSION NUMBER:		0001576280-25-000213
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20250630
FILED AS OF DATE:		20250702
DATE AS OF CHANGE:		20250702

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Talasaz AmirAli
		CENTRAL INDEX KEY:			0001753159
		ORGANIZATION NAME:           	

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-38683
		FILM NUMBER:		251103566

	MAIL ADDRESS:	
		STREET 1:		3100 HANOVER STREET
		CITY:			PALO ALTO
		STATE:			CA
		ZIP:			94304

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Guardant Health, Inc.
		CENTRAL INDEX KEY:			0001576280
		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-MEDICAL LABORATORIES [8071]
		ORGANIZATION NAME:           	08 Industrial Applications and Services
		EIN:				454139254
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		3100 HANOVER STREET
		CITY:			PALO ALTO
		STATE:			CA
		ZIP:			94304
		BUSINESS PHONE:		855-698-8887

	MAIL ADDRESS:	
		STREET 1:		3100 HANOVER STREET
		CITY:			PALO ALTO
		STATE:			CA
		ZIP:			94304
</SEC-HEADER>
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    <footnotes>
        <footnote id="F1">These shares were retained by the Company in order to meet the tax withholding obligations of the award-holder in connection with the vesting of an installment of the restricted stock units. The amount retained by the Company was not in excess of the amount of the tax liability.</footnote>
        <footnote id="F2">This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 17, 2024.</footnote>
        <footnote id="F3">The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $50.08 to $51.07 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.</footnote>
        <footnote id="F4">The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $51.08 to $51.94 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.</footnote>
        <footnote id="F5">This represents a restricted stock unit award granted on March 12, 2025 that vests in four equal installments on the last day of each calendar quarter, March 31, 2025, June 30, 2025, September 30, 2025, and December 31, 2025.</footnote>
        <footnote id="F6">Not applicable for Restricted Stock Units.</footnote>
        <footnote id="F7">This restricted stock unit award vested with respect to 1/3 of the shares on January 1, 2025. The remaining shares vest  quarterly for the remaining twenty-four months.</footnote>
    </footnotes>

    <remarks></remarks>

    <ownerSignature>
        <signatureName>/s/ John G. Saia, as attorney-in-fact for AmirAli Talasaz</signatureName>
        <signatureDate>2025-07-02</signatureDate>
    </ownerSignature>
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</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
