<SEC-DOCUMENT>0001652956-25-000005.txt : 20251203
<SEC-HEADER>0001652956-25-000005.hdr.sgml : 20251203
<ACCEPTANCE-DATETIME>20251203213021
ACCESSION NUMBER:		0001652956-25-000005
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20251201
FILED AS OF DATE:		20251203
DATE AS OF CHANGE:		20251203

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Monroe Terilyn J.
		CENTRAL INDEX KEY:			0001652956
		ORGANIZATION NAME:           	

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-38683
		FILM NUMBER:		251548099

	MAIL ADDRESS:	
		STREET 1:		3100 HANOVER STREET
		CITY:			PALO ALTO
		STATE:			CA
		ZIP:			94304

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Guardant Health, Inc.
		CENTRAL INDEX KEY:			0001576280
		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-MEDICAL LABORATORIES [8071]
		ORGANIZATION NAME:           	08 Industrial Applications and Services
		EIN:				454139254
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		3100 HANOVER STREET
		CITY:			PALO ALTO
		STATE:			CA
		ZIP:			94304
		BUSINESS PHONE:		855-698-8887

	MAIL ADDRESS:	
		STREET 1:		3100 HANOVER STREET
		CITY:			PALO ALTO
		STATE:			CA
		ZIP:			94304
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>wk-form4_1764815418.xml
<DESCRIPTION>FORM 4
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                <value>2025-12-01</value>
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                <transactionPricePerShare>
                    <value>0</value>
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                <value>2034-02-26</value>
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                <underlyingSecurityTitle>
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    <footnotes>
        <footnote id="F1">Represents the weighted average sales price per share. These shares were sold in multiple transactions at prices ranging  from $104.625 to $105.620. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of shares sold at each separate price within the range.</footnote>
        <footnote id="F2">Represents the weighted average sales price per share. These shares were sold in multiple transactions at prices ranging  from $105.625 to $106.620. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of shares sold at each separate price within the range.</footnote>
        <footnote id="F3">Represents the weighted average sales price per share. These shares were sold in multiple transactions at prices ranging  from $106.625 to $107.560. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of shares sold at each separate price within the range.</footnote>
        <footnote id="F4">Represents the weighted average sales price per share. These shares were sold in multiple transactions at prices ranging  from $107.730 to $107.970. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of shares sold at each separate price within the range.</footnote>
        <footnote id="F5">Represents the weighted average sales price per share. These shares were sold in multiple transactions at prices ranging  from $104.680 to $105.620. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of shares sold at each separate price within the range.</footnote>
        <footnote id="F6">Represents the weighted average sales price per share. These shares were sold in multiple transactions at prices ranging  from $105.680 to $106.670. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of shares sold at each separate price within the range.</footnote>
        <footnote id="F7">Represents the weighted average sales price per share. These shares were sold in multiple transactions at prices ranging  from $106.710 to $107.770. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of shares sold at each separate price within the range.</footnote>
        <footnote id="F8">This represents a stock option granted on February 26, 2024 that vests over a three-year period. 33% of the shares subject to such award vested on January 2, 2025 and the remaining 67% of the shares vests in equal monthly installments over the remaining two-year period thereafter.</footnote>
        <footnote id="F9">This represents a stock option award granted on November 8, 2024 that vests over a three-year period. 33% of the shares subject to such award vested on October 1, 2025, and the remaining 67% of the shares vests in equal monthly installments over the remaining two-year period thereafter.</footnote>
    </footnotes>

    <remarks></remarks>

    <ownerSignature>
        <signatureName>/s/ John G. Saia, as attorney-in-fact for Tarilyn J. Monroe</signatureName>
        <signatureDate>2025-12-02</signatureDate>
    </ownerSignature>
</ownershipDocument>
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</SEC-DOCUMENT>
