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<SEC-DOCUMENT>0000012208-09-000030.txt : 20090522
<SEC-HEADER>0000012208-09-000030.hdr.sgml : 20090522
<ACCEPTANCE-DATETIME>20090520172913
ACCESSION NUMBER:		0000012208-09-000030
CONFORMED SUBMISSION TYPE:	8-K
PUBLIC DOCUMENT COUNT:		4
CONFORMED PERIOD OF REPORT:	20090518
ITEM INFORMATION:		Entry into a Material Definitive Agreement
ITEM INFORMATION:		Regulation FD Disclosure
ITEM INFORMATION:		Financial Statements and Exhibits
FILED AS OF DATE:		20090520
DATE AS OF CHANGE:		20090520

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			BIO RAD LABORATORIES INC
		CENTRAL INDEX KEY:			0000012208
		STANDARD INDUSTRIAL CLASSIFICATION:	LABORATORY ANALYTICAL INSTRUMENTS [3826]
		IRS NUMBER:				941381833
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		8-K
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-07928
		FILM NUMBER:		09843549

	BUSINESS ADDRESS:	
		STREET 1:		1000 ALFRED NOBEL DR
		CITY:			HERCULES
		STATE:			CA
		ZIP:			94547
		BUSINESS PHONE:		5107247000
</SEC-HEADER>
<DOCUMENT>
<TYPE>8-K
<SEQUENCE>1
<FILENAME>f8k05202009.htm
<DESCRIPTION>8K 05/18/2009
<TEXT>
<!doctype html public "-//IETF//DTD HTML//EN">
<HTML>f8K05182009.htm FOR BIO-RAD LABORATORIES, INC.
<HEAD>
<TITLE>UNITED STATES</TITLE>
<META NAME="author" CONTENT="Stephanie Trudrunng">
<META NAME="date" CONTENT="04/21/2008">
</HEAD>
<BODY style="line-height:12pt; font-family:Times New Roman; font-size:10pt; color:#000000">
<DIV style="width:643.2px"><P style="margin:0px" align=right><BR></P>
<P style="margin:0px"><BR></P>
<P style="margin:0px"><BR></P>
<P style="margin:0px; padding-top:4px; border-top:1px solid #7F0000"><BR></P>
<P style="margin:0px"><BR></P>
<P style="line-height:21.333px; margin:0px; font-size:18.667px" align=center><B>UNITED STATES</B></P>
<P style="line-height:21.333px; margin:0px; font-size:18.667px" align=center><B>SECURITIES AND EXCHANGE COMMISSION</B></P>
<P style="line-height:21.333px; margin:0px; font-size:18.667px" align=center><B>Washington, D.C. 20549</B></P>
<P style="margin:0px"><BR></P>
<P style="line-height:24px; margin:0px; font-size:21.333px" align=center><B>FORM 8-K</B></P>
<P style="margin:0px"><BR></P>
<P style="margin:0px; padding-top:4px; border-top:1px solid #7F0000"><BR></P>
<P style="line-height:10.667px; margin:0px"><BR></P>
<P style="line-height:21.333px; margin:0px; font-size:18.667px" align=center><B>CURRENT REPORT</B></P>
<P style="line-height:17.333px; margin:0px; font-size:14.667px" align=center><B>Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934</B></P>
<P style="margin:0px"><BR></P>
<P style="line-height:21.333px; margin:0px; font-size:18.667px" align=center><B>Date of Report: May 18, 2009</B></P>
<P style="margin:0px" align=center><B>(Date of earliest event reported)</B></P>
<P style="margin:0px"><BR></P>
<P style="line-height:10.667px; margin:0px; padding-top:4px; border-top:1px solid #7F0000"><BR></P>
<P style="margin:0px"><BR></P>
<P style="line-height:26.667px; margin:0px; font-size:24px" align=center><B>BIO-RAD LABORATORIES, INC.</B></P>
<P style="margin:0px" align=center><B>(Exact name of registrant as specified in its charter)</B></P>
<P style="margin:0px"><BR></P>
<P style="margin:0px; padding-top:4px; border-top:1px solid #7F0000"><BR></P>
<P style="line-height:12px; margin:0px"><BR></P>
<P style="line-height:21.333px; margin:0px; font-size:18.667px" align=center><B>Commission File Number: 1-7928</B></P>
<P style="margin:0px"><BR></P>
<TABLE style="font-size:13.333px" cellspacing=0 align=center><TR><TD width=360></TD><TD width=7.133></TD><TD width=352.8></TD></TR>
<TR><TD width=360><P style="margin:0px; font-size:10.667px">&nbsp;</P>
</TD><TD valign=bottom width=7.133><P style="margin:0px; font-size:10.667px">&nbsp;</P>
</TD><TD width=352.8><P style="margin:0px; font-size:10.667px">&nbsp;</P>
</TD></TR>
<TR><TD valign=top width=360><P style="line-height:18.667px; margin:0px; font-size:16px" align=center><B>Delaware</B></P>
</TD><TD valign=bottom width=7.133><P style="margin:0px; font-size:16px">&nbsp;</P>
</TD><TD valign=top width=352.8><P style="line-height:18.667px; margin:0px; font-size:16px" align=center><B>94-1381833</B></P>
</TD></TR>
<TR><TD valign=top width=360><P style="margin:0px" align=center><B>(State or other jurisdiction of</B></P>
<P style="margin:0px" align=center><B>incorporation or organization)</B></P>
</TD><TD valign=bottom width=7.133><P style="margin:0px">&nbsp;</P>
</TD><TD valign=top width=352.8><P style="margin:0px" align=center><B>(I.R.S. Employer</B></P>
<P style="margin:0px" align=center><B>Identification No.)</B></P>
</TD></TR>
</TABLE>
<P style="line-height:10.667px; margin:0px"><BR></P>
<P style="line-height:10.667px; margin:0px"><BR></P>
<P style="line-height:18.667px; margin:0px; font-size:16px" align=center><B>1000 Alfred Nobel Dr.</B></P>
<P style="line-height:18.667px; margin:0px; font-size:16px" align=center><B>Hercules, California 94547</B></P>
<P style="margin:0px" align=center><B>(Address of principal executive offices, including zip code)</B></P>
<P style="margin:0px"><BR></P>
<P style="line-height:18.667px; margin:0px; font-size:16px" align=center><B>(510) 724-7000</B></P>
<P style="margin:0px" align=center><B>(Registrant&#146;s telephone number, including area code)</B></P>
<P style="margin:0px"><BR></P>
<P style="line-height:10.667px; margin:0px"><BR></P>
<P style="line-height:10.667px; margin:0px; padding-top:4px; border-top:1px solid #7F0000"><BR></P>
<P style="margin:0px"><BR></P>
<P style="line-height:normal; margin:0px; font-size:10.667px">Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the <BIG>following provisions:</BIG></P>
<P style="margin:0px">&nbsp;</P>
<TABLE style="font-size:13.333px" cellspacing=0><TR><TD width=28.8></TD><TD width=562.733></TD></TR>
<TR><TD valign=top width=28.8><P style="margin:0px; font-family:Wingdings"><FONT FACE="Wingdings">&#168;</FONT></P>
</TD><TD valign=top width=562.733><P style="margin:0px"><FONT FACE="Times New Roman">Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)</FONT></P>
</TD></TR>
</TABLE>
<P style="margin:0px">&nbsp;</P>
<TABLE style="font-size:13.333px" cellspacing=0><TR><TD width=28.8></TD><TD width=565.6></TD></TR>
<TR><TD valign=top width=28.8><P style="margin:0px; font-family:Wingdings"><FONT FACE="Wingdings">&#168;</FONT></P>
</TD><TD valign=top width=565.6><P style="margin:0px"><FONT FACE="Times New Roman">Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)</FONT></P>
</TD></TR>
</TABLE>
<P style="margin:0px">&nbsp;</P>
<TABLE style="font-size:13.333px" cellspacing=0><TR><TD width=28.8></TD><TD width=616.267></TD></TR>
<TR><TD valign=top width=28.8><P style="margin:0px; font-family:Wingdings"><FONT FACE="Wingdings">&#168;</FONT></P>
</TD><TD valign=top width=616.267><P style="margin:0px"><FONT FACE="Times New Roman">Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))</FONT></P>
</TD></TR>
</TABLE>
<P style="margin:0px">&nbsp;</P>
<TABLE style="font-size:13.333px" cellspacing=0><TR><TD width=28.8></TD><TD width=615></TD></TR>
<TR><TD valign=top width=28.8><P style="margin:0px; font-family:Wingdings"><FONT FACE="Wingdings">&#168;</FONT></P>
</TD><TD valign=top width=615><P style="margin:0px"><FONT FACE="Times New Roman">Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))</FONT></P>
</TD></TR>
</TABLE>
<P style="margin:0px"><BR></P>
<P style="margin:0px"><BR>
<BR></P>
<P style="margin:0px; page-break-before:always" align=right><BR></P>
<P style="margin:0px"><BR></P>
<P style="margin:0px"><B>&nbsp;</B></P>
<TABLE style="font-size:13.333px" cellspacing=0><TR><TD width=83.333></TD><TD width=360.667></TD></TR>
<TR><TD valign=top width=83.333><P style="line-height:17.333px; margin:0px; font-size:14.667px" align=justify><B>Item 1.01</B></P>
</TD><TD valign=top width=360.667><P style="line-height:17.333px; margin:0px; font-size:14.667px"><B>Entry into a Material Definitive Agreement.</B></P>
</TD></TR>
</TABLE>
<P style="margin:0px"><BR></P>
<P style="line-height:17.333px; margin:0px; padding-right:24px; text-indent:48px; font-size:14.667px">Amendment No. 3 to Amended and Restated Credit Agreement (&#147;Amendment No. 3&#148;), by and among Bio-Rad Laboratories, Inc. (the &#147;Company&#148;), the lenders referred to therein, and JPMorgan Chase Bank, N.A. (successor by merger to Bank One, NA (Main Office Chicago), as lender and contractual representative), executed as of January 17, 2008, became effective by its terms as of May 18, 2009, which amends certain provisions of that certain Amended and Restated Credit Agreement dated as of June 21, 2005, as amended on August 26, 2005 and September 27, 2007 (the &#147;Credit Agreement&#148;), including, among other things, (i) increasing the amount of certain unsecured or subordinated indebtedness permitted by the Credit Agreement in an amount up to $300 million under certain conditions, and (ii) increasing the permitted maximum leverage ratio, as such definition has been amended, from 3.25 to 1.00 to 
3.50 to 1.00 under certain conditions.</P>
<P style="margin:0px"><BR></P>
<P style="line-height:normal; margin:0px; padding-right:24px; text-indent:48px; font-size:14.667px">The description of Amendment No. 3 does not purport to be complete and is qualified in its entirety by reference to Amendment No. 3, which is filed as Exhibit 10.1 hereto and incorporated by reference herein.</P>
<P style="margin:0px"><BR></P>
<TABLE style="font-size:13.333px" cellspacing=0><TR><TD width=83.333></TD><TD width=285.933></TD></TR>
<TR><TD valign=top width=83.333><P style="line-height:17.333px; margin:0px; font-size:14.667px" align=justify><B>Item 7.01</B></P>
</TD><TD valign=top width=285.933><P style="line-height:17.333px; margin:0px; font-size:14.667px"><B>Regulation FD Disclosure.</B></P>
</TD></TR>
</TABLE>
<P style="margin:0px"><BR></P>
<P style="line-height:17.333px; margin:0px; padding-right:24px; text-indent:48px; font-size:14.667px">On May 19, 2009, the Company issued a press release announcing a proposed private offering of $250 million of senior subordinated notes. &nbsp;A copy of the press release is attached as Exhibit 99.1 hereto.</P>
<P style="margin:0px"><BR></P>
<P style="line-height:17.333px; margin:0px; padding-right:24px; text-indent:48px; font-size:14.667px">On May 19, 2009, the Company announced the pricing of its offering of $300 million of senior subordinated notes due 2016 to qualified institutional buyers pursuant to Rule 144A and in offshore transactions pursuant to Regulation S under the Securities Act of 1933, as amended. &nbsp;A copy of the press release is attached as Exhibit 99.2 hereto.</P>
<P style="margin:0px"><BR></P>
<P style="margin:0px"><BR></P>
<TABLE style="font-size:13.333px" cellspacing=0><TR><TD width=83.333></TD><TD width=492.667></TD></TR>
<TR><TD valign=top width=83.333><P style="line-height:17.333px; margin:0px; font-size:14.667px"><B>ITEM 9.01</B></P>
</TD><TD valign=top width=492.667><P style="line-height:17.333px; margin:0px; font-size:14.667px"><B>Financial Statements and Exhibits.</B></P>
</TD></TR>
</TABLE>
<P style="margin:0px"><BR></P>
<P style="margin:0px"><BR></P>
<TABLE style="font-size:13.333px" cellspacing=0><TR><TD width=60></TD><TD width=24></TD><TD width=497.533></TD></TR>
<TR><TD width=60><P style="line-height:17.333px; margin:0px; font-size:14.667px">(d)</P>
</TD><TD valign=bottom width=521.533 colspan=2><P style="line-height:17.333px; margin:0px; font-size:14.667px">Exhibits.</P>
</TD></TR>
<TR><TD width=581.533 colspan=3><P style="margin:0px">&nbsp;</P>
<P style="line-height:17.333px; margin:0px">&nbsp;The following exhibits are filed with the Form 8-K:</P>
</TD></TR>
<TR><TD style="border-bottom:1px solid #000000" valign=bottom width=60><P style="margin:0px"><B>Exhibit</B></P>
<P style="margin:0px"><B>Number&nbsp;</B></P>
</TD><TD valign=bottom width=24><P style="margin:0px">&nbsp;</P>
</TD><TD style="border-bottom:1px solid #000000" valign=bottom width=497.533><P style="margin:0px"><BR></P>
<P style="margin:0px"><B>Description</B></P>
</TD></TR>
<TR><TD valign=top width=60><P style="margin-top:4.467px; margin-bottom:0px" align=right>10.1</P>
</TD><TD valign=bottom width=24><P style="margin-top:4.867px; margin-bottom:0px; font-size:14.667px">&nbsp;</P>
</TD><TD valign=bottom width=497.533><P style="margin:0px">Amendment No. 3 to Amended and Restated Credit Agreement, by and among Bio-Rad Laboratories, Inc., the lenders referred to herein, and JPMorgan Chase Bank, N.A. as lender and contractual representative, executed as of January 17, 2008, effective by its terms as of May 18, 2009</P>
</TD></TR>
<TR><TD valign=top width=60><P style="font-size:2pt">&nbsp;</P></TD><TD valign=bottom width=24><P style="font-size:2pt">&nbsp;</P></TD><TD valign=bottom width=497.533><P style="font-size:2pt">&nbsp;</P></TD></TR>
<TR><TD valign=top width=60><P style="margin-top:2.2px; margin-bottom:0px" align=right>99.1</P>
</TD><TD valign=bottom width=24><P style="font-size:2pt">&nbsp;</P></TD><TD valign=bottom width=497.533><P style="margin-top:2.2px; margin-bottom:0px">Press release dated May 19, 2009</P>
</TD></TR>
<TR><TD valign=top width=60><P style="font-size:2pt">&nbsp;</P></TD><TD valign=bottom width=24><P style="font-size:2pt">&nbsp;</P></TD><TD valign=bottom width=497.533><P style="font-size:2pt">&nbsp;</P></TD></TR>
<TR><TD valign=top width=60><P style="margin-top:2.2px; margin-bottom:0px" align=right>99.2</P>
</TD><TD valign=bottom width=24><P style="font-size:2pt">&nbsp;</P></TD><TD valign=bottom width=497.533><P style="margin-top:2.2px; margin-bottom:0px">Press release dated May 19, 2009</P>
</TD></TR>
</TABLE>
<P style="margin:0px" align=center><BR></P>
<P style="margin:0px" align=center><BR>
<BR></P>
<P style="margin:0px; page-break-before:always" align=right><BR></P>
<P style="margin:0px"><BR></P>
<P style="margin:0px" align=center><B>SIGNATURES</B></P>
<P style="margin:0px">&nbsp;</P>
<P style="margin:0px">Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.</P>
<P style="margin:0px">&nbsp;&nbsp;</P>
<TABLE style="font-size:13.333px" cellspacing=0><TR><TD width=50.867></TD><TD width=136.333></TD><TD width=29.467></TD><TD width=29.467></TD><TD width=4></TD><TD width=253.867></TD></TR>
<TR><TD valign=top width=50.867><P style="font-size:2pt">&nbsp;</P></TD><TD width=136.333><P style="font-size:2pt">&nbsp;</P></TD><TD valign=top width=29.467><P style="font-size:2pt">&nbsp;</P></TD><TD valign=top width=29.467><P style="font-size:2pt">&nbsp;</P></TD><TD valign=bottom width=257.867 colspan=2><P style="font-size:2pt">&nbsp;</P></TD></TR>
<TR><TD valign=top width=50.867><P style="font-size:2pt">&nbsp;</P></TD><TD width=136.333><P style="font-size:2pt">&nbsp;</P></TD><TD valign=top width=29.467><P style="font-size:2pt">&nbsp;</P></TD><TD valign=top width=29.467><P style="font-size:2pt">&nbsp;</P></TD><TD valign=bottom width=257.867 colspan=2><P style="font-size:2pt">&nbsp;</P></TD></TR>
<TR><TD valign=top width=50.867><P style="font-size:2pt">&nbsp;</P></TD><TD width=136.333><P style="font-size:2pt">&nbsp;</P></TD><TD valign=top width=29.467><P style="font-size:2pt">&nbsp;</P></TD><TD valign=top width=287.333 colspan=3><P style="line-height:17.333px; margin:0px; font-size:14.667px">BIO-RAD LABORATORIES, INC.</P>
</TD></TR>
<TR><TD valign=top width=50.867><P style="font-size:2pt">&nbsp;</P></TD><TD width=136.333><P style="font-size:2pt">&nbsp;</P></TD><TD valign=top width=29.467><P style="font-size:2pt">&nbsp;</P></TD><TD valign=top width=29.467><P style="font-size:2pt">&nbsp;</P></TD><TD valign=bottom width=257.867 colspan=2><P style="font-size:2pt">&nbsp;</P></TD></TR>
<TR><TD valign=top width=50.867><P style="line-height:17.333px; margin:0px; font-size:14.667px">Date:</P>
</TD><TD style="border-bottom:1px solid #000000" width=136.333><P style="line-height:17.333px; margin:0px; font-size:14.667px">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;May 20, 2009</P>
</TD><TD valign=top width=29.467><P style="font-size:2pt">&nbsp;</P></TD><TD valign=top width=29.467><P style="line-height:17.333px; margin:0px; font-size:14.667px">By:</P>
</TD><TD style="border-bottom:1px solid #000000" valign=bottom width=257.867 colspan=2><P style="line-height:17.333px; margin:0px; font-size:14.667px">/s/ Christine A. Tsingos</P>
</TD></TR>
<TR><TD valign=top width=50.867><P style="font-size:2pt">&nbsp;</P></TD><TD valign=top width=136.333><P style="font-size:2pt">&nbsp;</P></TD><TD valign=top width=29.467><P style="font-size:2pt">&nbsp;</P></TD><TD valign=bottom width=29.467><P style="margin:0px; font-size:14.667px">&nbsp;</P>
</TD><TD valign=bottom width=4><P style="font-size:2pt">&nbsp;</P></TD><TD valign=bottom width=253.867><P style="line-height:17.333px; margin:0px; font-size:14.667px">Christine A. Tsingos </P>
</TD></TR>
<TR><TD valign=top width=50.867><P style="font-size:2pt">&nbsp;</P></TD><TD valign=top width=136.333><P style="font-size:2pt">&nbsp;</P></TD><TD valign=top width=29.467><P style="font-size:2pt">&nbsp;</P></TD><TD valign=bottom width=29.467><P style="font-size:2pt">&nbsp;</P></TD><TD valign=bottom width=4><P style="font-size:2pt">&nbsp;</P></TD><TD valign=bottom width=253.867><P style="line-height:17.333px; margin:0px; font-size:14.667px">Vice President, Chief Financial Officer</P>
</TD></TR>
<TR><TD valign=top width=50.867><P style="font-size:2pt">&nbsp;</P></TD><TD valign=top width=136.333><P style="margin:0px">&nbsp;</P>
</TD><TD valign=top width=29.467><P style="font-size:2pt">&nbsp;</P></TD><TD valign=bottom width=29.467><P style="margin:0px">&nbsp;</P>
</TD><TD valign=bottom width=4><P style="margin:0px">&nbsp;</P>
</TD><TD valign=bottom width=253.867><P style="font-size:2pt">&nbsp;</P></TD></TR>
</TABLE>
<P style="margin:0px"><BR></P>
<P style="margin:0px"><BR></P>
<A NAME="id_11"></A><A NAME="id_12"></A><P style="margin:0px"><BR></P>
<P style="margin:0px" align=center><B>EXHIBIT INDEX</B></P>
<P style="margin:0px">&nbsp;</P>
<TABLE style="font-size:13.333px" cellspacing=0 align=center><TR><TD width=58.867></TD><TD width=12></TD><TD width=426.067></TD></TR>
<TR><TD width=58.867><P style="margin:0px; font-size:14.667px">&nbsp;</P>
</TD><TD valign=bottom width=12><P style="margin:0px; font-size:14.667px">&nbsp;</P>
</TD><TD width=426.067><P style="margin:0px; font-size:14.667px">&nbsp;</P>
</TD></TR>
<TR><TD style="border-bottom:1px solid #000000" valign=bottom width=58.867><P style="margin:0px"><B>Exhibit</B></P>
<P style="margin:0px"><B>Number</B></P>
</TD><TD valign=bottom width=12><P style="margin:0px">&nbsp;</P>
</TD><TD style="border-bottom:1px solid #000000" valign=bottom width=426.067><P style="margin:0px"><BR></P>
<P style="margin:0px"><B>Description</B></P>
</TD></TR>
<TR><TD valign=top width=58.867><P style="margin:0px" align=center>10.1</P>
</TD><TD valign=bottom width=12><P style="font-size:2pt">&nbsp;</P></TD><TD valign=bottom width=426.067><P style="margin:0px">Amendment No. 3 to Amended and Restated Credit Agreement, by and among Bio-Rad Laboratories, Inc., the lenders referred to herein, and JPMorgan Chase Bank, N.A. as lender and contractual representative, executed as of January 17, 2008, effective by its terms as of May 18, 2009.</P>
</TD></TR>
<TR><TD valign=top width=58.867><P style="font-size:2pt">&nbsp;</P></TD><TD valign=bottom width=12><P style="font-size:2pt">&nbsp;</P></TD><TD valign=bottom width=426.067><P style="font-size:2pt">&nbsp;</P></TD></TR>
<TR><TD valign=top width=58.867><P style="margin:0px" align=center>99.1</P>
</TD><TD valign=bottom width=12><P style="font-size:2pt">&nbsp;</P></TD><TD valign=bottom width=426.067><P style="margin:0px">Press release dated May 19, 2009</P>
</TD></TR>
<TR><TD valign=top width=58.867><P style="font-size:2pt">&nbsp;</P></TD><TD valign=bottom width=12><P style="font-size:2pt">&nbsp;</P></TD><TD valign=bottom width=426.067><P style="font-size:2pt">&nbsp;</P></TD></TR>
<TR><TD valign=top width=58.867><P style="margin:0px" align=center>99.2</P>
</TD><TD valign=bottom width=12><P style="font-size:2pt">&nbsp;</P></TD><TD valign=bottom width=426.067><P style="margin:0px">Press release dated May 19, 2009</P>
</TD></TR>
</TABLE>
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<DOCUMENT>
<TYPE>EX-10
<SEQUENCE>2
<FILENAME>exhibit101.htm
<DESCRIPTION>EXHIBIT 10.1
<TEXT>
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<TITLE>Converted by EDGARwiz</TITLE>
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<DIV style="width:624px"><P style="margin-top:0px; margin-bottom:15.333px" align=right><BR></P>
<P style="line-height:17.333px; margin-top:0px; margin-bottom:14.667px; font-size:14.667px" align=right><B><U>Exhibit 10.1</U></B></P>
<P style="line-height:18px; margin-top:0px; margin-bottom:15.333px; font-size:15.333px" align=right><B>EXECUTION COPY</B></P>
<P style="line-height:18px; margin-top:15.333px; margin-bottom:15.333px; font-size:15.333px" align=center><B>AMENDMENT NO. 3 TO AMENDED AND RESTATED CREDIT AGREEMENT</B></P>
<P style="line-height:18px; margin-top:0px; margin-bottom:15.333px; text-indent:48px; font-size:15.333px" align=justify>This Amendment No. 3 (this &#147;<U>Amendment</U>&#148;) is entered into as of January 17, 2008 by and among BIO-RAD LABORATORIES, INC., a Delaware corporation (the &#147;<U>Borrower</U>&#148;), certain of the financial institutions party to the below-defined Credit Agreement (collectively, the &#147;<U>Lenders</U>&#148;) and JPMORGAN CHASE BANK, N.A., as one of the Lenders and in its capacity as contractual representative (the &#147;<U>Agent</U>&#148;) on behalf of itself and the other Lenders.</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:15.333px; font-size:15.333px" align=center>RECITALS:</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:15.333px; text-indent:48px; font-size:15.333px" align=justify>WHEREAS, the Borrower, the Lenders and the Agent have entered into that certain Amended and Restated Credit Agreement dated as of June 21, 2005 (as amended prior to the date hereof, the &#147;<U>Credit Agreement</U>&#148;);</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:15.333px; text-indent:48px; font-size:15.333px" align=justify>WHEREAS, the Borrower wishes to amend the Credit Agreement in certain respects and the Lenders and the Agent are willing to amend the Credit Agreement on the terms and conditions set forth herein;</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:15.333px; text-indent:48px; font-size:15.333px" align=justify>NOW, THEREFORE, for good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, the parties hereto hereby agree as follows:</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:-18px; text-indent:48px; font-size:15.333px" align=justify>1.</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:15.333px; text-indent:96px; font-size:15.333px" align=justify><U>Defined Terms</U>. &nbsp;Capitalized terms used herein and not otherwise defined herein shall have the meanings attributed to such terms in the Credit Agreement.</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:-18px; text-indent:48px; font-size:15.333px" align=justify>2.</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:15.333px; text-indent:96px; font-size:15.333px" align=justify><U>Amendments to Credit Agreement</U>. Upon the Effective Date, in accordance with the provisions of <U>Section 3</U> below, the Credit Agreement is hereby amended as follows: </P>
<P style="line-height:18.667px; margin-top:0px; margin-bottom:-18.667px; padding-left:180px; text-indent:48px; font-size:16px" align=justify>(a)</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:15.333px; padding-left:180px; text-indent:108px; font-size:15.333px" align=justify><U>Section 1.01</U> of the Credit Agreement is hereby amended to add the following new defined terms thereto in the appropriate alphabetical order:</P>
<P style="line-height:18px; margin:0px; padding-left:96px; text-indent:48px; font-size:15.333px" align=justify><I>&#147;Permitted Senior Unsecured Note Indebtedness&#148; means Indebtedness of the Borrower in principal amount not to exceed (when aggregated with the Permitted Subordinated Indebtedness described in clause (iv) of the definition of &#147;Permitted Subordinated Indebtedness&#148;) $300,000,000 in the form of senior unsecured notes, the maturity of which is at least six months later than the Facility Termination Date and all of the terms and conditions of which are reasonably acceptable to the Agent.</I></P>
<P style="margin:0px" align=justify><BR></P>
<P style="line-height:18px; margin:0px; padding-left:96px; text-indent:48px; font-size:15.333px" align=justify><I>&#147;Senior Unsecured Note Indebtedness&#148; means the Permitted Senior Unsecured Note Indebtedness and any Permitted Refinancing in respect thereof.</I></P>
<P style="margin:0px" align=justify><BR></P>
<P style="margin:0px" align=justify><BR>
<BR></P>
<P style="line-height:18px; margin:0px; padding-left:96px; text-indent:48px; font-size:15.333px; page-break-before:always" align=justify><I>&#147;Specified Issuance&#148; means the issuance of new Subordinated Indebtedness or new Senior Unsecured Note Indebtedness in an aggregate principal amount in excess of $200,000,000 on or after January 17, 2008.</I></P>
<P style="margin:0px" align=justify><BR></P>
<P style="line-height:18.667px; margin-top:0px; margin-bottom:-18.667px; padding-left:180px; text-indent:48px; font-size:16px" align=justify>(b)<U><A NAME="B000001T"></A></U></P>
<P style="line-height:18px; margin-top:0px; margin-bottom:15.333px; padding-left:180px; text-indent:108px; font-size:15.333px" align=justify><A HREF="#T000001B"><U><SUP></SUP></U></A><U></U></P>
<P style="line-height:18px; margin-top:0px; margin-bottom:15.333px; padding-left:180px; text-indent:48px; font-size:15.333px" align=justify><U>Section 1.01</U> of the Credit Agreement is hereby amended to restate clause (v) of the definition of &#147;Change in Control&#148; in its entirety as follows:</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:-18px; padding-left:96px; text-indent:48px; font-size:15.333px" align=justify><I>(v)</I></P>
<P style="line-height:18px; margin:0px; padding-left:96px; text-indent:96px; font-size:15.333px" align=justify><I>any &#147;Change in Control&#148; or &#147;Change of Control&#148; as defined in any agreement governing Subordinated Indebtedness or Senior Unsecured Note Indebtedness occurs and as a result thereof the Borrower is required to prepay or repurchase, or make an offer to prepay or repurchase, such Subordinated Indebtedness or Senior Unsecured Note Indebtedness, as applicable.</I></P>
<P style="margin:0px" align=justify><BR></P>
<P style="line-height:18.667px; margin-top:0px; margin-bottom:-18.667px; padding-left:180px; text-indent:48px; font-size:16px" align=justify>(c)</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:15.333px; padding-left:180px; text-indent:108px; font-size:15.333px" align=justify><U>Section 1.01</U> of the Credit Agreement is hereby amended to restate clause (iii) of the definition of &#147;Consolidated Funded Indebtedness&#148; in its entirety as follows:</P>
<P style="line-height:18px; margin:0px; padding-left:96px; text-indent:48px; font-size:15.333px" align=justify><I>(iii) any amount of Subordinated Indebtedness or Senior Unsecured Note Indebtedness with respect to which the Borrower has exercised its right to elect to apply, and has so applied, legal defeasance and discharge, all in accordance with the terms of the indenture or other agreement governing such Subordinated Indebtedness or Senior Unsecured Note Indebtedness, as applicable.</I></P>
<P style="margin:0px" align=justify><BR></P>
<P style="line-height:18.667px; margin-top:0px; margin-bottom:-18.667px; padding-left:180px; text-indent:48px; font-size:16px" align=justify>(d)</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:15.333px; padding-left:180px; text-indent:108px; font-size:15.333px" align=justify><U>Section 1.01</U> of the Credit Agreement is hereby amended to restate the definition of &#147;Leverage Ratio&#148; in its entirety as follows:</P>
<P style="line-height:18px; margin:0px; padding-left:96px; text-indent:48px; font-size:15.333px" align=justify><I>&#147;Leverage Ratio&#148; means, as of any date of calculation, the ratio of (i) (x) Consolidated Funded Indebtedness outstanding on such date <U>minus</U>, only if the Borrower makes a Specified Issuance, (y) the <U>lesser</U> of (A) the sum of all unencumbered cash and Cash Equivalent Investments of the Borrower held on deposit in the United States of America with (1) Lenders or Affiliates of Lenders at a Lending Installation and (2) financial institutions which are not Lenders or Affiliates of Lenders in account(s) which are subject to control agreements reasonably satisfactory to the Administrative Agent and (B) $100,000,000, to (ii) Consolidated EBITDA for the Borrower&#146;s then most-recently ended four fiscal quarters.</I></P>
<P style="margin:0px"><BR></P>
<P style="line-height:18.667px; margin-top:0px; margin-bottom:-18.667px; padding-left:180px; text-indent:48px; font-size:16px" align=justify>(e)</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:15.333px; padding-left:180px; text-indent:108px; font-size:15.333px" align=justify><U>Section 1.01</U> of the Credit Agreement is hereby amended to restate the definition of &#147;Permitted Refinancing&#148; in its entirety as follows:</P>
<P style="line-height:18px; margin:0px; padding-left:96px; text-indent:48px; font-size:15.333px" align=justify><I>&#147;Permitted Refinancing&#148; means Indebtedness of the Borrower the proceeds of which are used to refinance Subordinated Indebtedness or Senior Unsecured Note Indebtedness, as applicable, provided that (i) the principal amount of such Indebtedness does not exceed that of the Subordinated Indebtedness or Senior Unsecured Note Indebtedness, as applicable, being refinanced immediately before the respective refinancing is consummated (plus the amount of any premium, fees, expenses and/or accrued interest actually paid on the Subordinated Indebtedness or Senior Unsecured Note Indebtedness, as applicable, so refinanced), (ii) all net proceeds of such Indebtedness are substantially concurrently (or, if pursuant to a </I></P>
<P style="margin:0px" align=justify><BR>
<BR></P>
<P style="margin:0px"><BR></P>
<P style="margin:0px"><BR></P>
<P style="line-height:normal; margin:0px; padding-left:96px; font-size:15.333px; page-break-before:always" align=justify><I>redemption notice or similar instrument, within 45 days) applied to permanently repay the Subordinated Indebtedness or Senior Unsecured Note Indebtedness, as applicable, being refinanced, (iii) such Indebtedness (if such Indebtedness is refinancing any Subordinated Indebtedness) is subordinated in right of payment to the Obligations at least to the same extent as the Subordinated Indebtedness being refinanced, (iv) such Indebtedness is scheduled to mature (as determined under Agreement Accounting Principles) no earlier than the earlier of (A) the maturity date of the Subordinated Indebtedness or Senior Unsecured Note Indebtedness, as applicable, being refinanced and (B) the Facility Termination Date, (v) such Indebtedness has an Average Life at the time such Indebtedness is incurred that is equal to or greater than the lesser of (A) the Average Life of the Subordinated Indebtedness or S
enior Unsecured Note Indebtedness, as applicable, being refinanced and (B) the period from the date such Indebtedness is incurred to the Facility Termination Date, and (vi) the terms of such Indebtedness (including, without limitation, terms relating to security, covenants, events of default and remedies, but excluding interest rates and other economic terms so long as they are based on then current market conditions) are not less favorable to the Borrower or to the Lenders than those applicable to the</I> <I>Subordinated Indebtedness or Senior Unsecured Note Indebtedness, as applicable, being refinanced.</I></P>
<P style="margin:0px" align=justify><BR></P>
<P style="line-height:18.667px; margin-top:0px; margin-bottom:-18.667px; padding-left:180px; text-indent:48px; font-size:16px" align=justify>(f)</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:15.333px; padding-left:180px; text-indent:108px; font-size:15.333px" align=justify><U>Section 1.01</U> of the Credit Agreement is hereby amended to restate the definition of &#147;Permitted Subordinated Indebtedness&#148; in its entirety as follows:</P>
<P style="line-height:18px; margin:0px; padding-left:96px; text-indent:48px; font-size:15.333px" align=justify><I>&#147;Permitted Subordinated Indebtedness&#148; means (i) the Borrower&#146;s 7.50% Senior Subordinated Notes due 2013 in the principal amount of $225,000,000 outstanding on the Closing Date, (ii) the Borrower&#146;s 6.125% Senior Subordinated Notes due 2014 in the principal amount of $200,000,000 outstanding on the Closing Date, (iii) up to $25,000,000 of additional Indebtedness of the Borrower, the payment of which is subordinated to payment of the Secured Obligations, the maturity of which is at least six months later than the Facility Termination Date and all of the terms and conditions of which are reasonably acceptable to the Agent and (iv) additional Indebtedness of the Borrower in principal amount not to exceed (when aggregated with the Permitted Senior Unsecured Note Indebtedness) $300,000,000 in the form of senior subordinated notes, the payment of which is subordinated to payment of th
e Secured Obligations, the maturity of which is at least six months later than the Facility Termination Date and all of the terms and conditions of which are reasonably acceptable to the Agent. &nbsp;Subordination terms and other terms and conditions substantially similar to those contained in the Indenture dated as of December 21, 2004 between the Borrower and Wells Fargo Bank, National Association, as Trustee, shall be deemed to be reasonably acceptable.</I></P>
<P style="margin:0px" align=justify><BR></P>
<P style="line-height:18.667px; margin-top:0px; margin-bottom:-18.667px; padding-left:180px; text-indent:48px; font-size:16px" align=justify>(g)</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:15.333px; padding-left:180px; text-indent:108px; font-size:15.333px" align=justify><U>Section 1.01</U> of the Credit Agreement is hereby amended to restate the definition of &#147;Subordinated Indebtedness&#148; in its entirety as follows:</P>
<P style="line-height:18px; margin:0px; padding-left:96px; text-indent:48px; font-size:15.333px" align=justify><I>&#147;Subordinated Indebtedness&#148; means the Permitted Subordinated Indebtedness and any Permitted Refinancing in respect thereof.</I></P>
<P style="margin:0px" align=justify><BR></P>
<P style="margin:0px" align=justify><BR>
<BR></P>
<P style="margin:0px"><BR></P>
<P style="margin:0px"><BR></P>
<P style="line-height:18.667px; margin-top:0px; margin-bottom:-18.667px; padding-left:180px; text-indent:48px; font-size:16px; page-break-before:always" align=justify>(h)</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:15.333px; padding-left:180px; text-indent:108px; font-size:15.333px" align=justify><U>Section 6.11</U> of the Credit Agreement is hereby amended to restate <U>clause (iv)</U> thereof in its entirety as follows:</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:-18px; padding-left:96px; text-indent:48px; font-size:15.333px" align=justify><I>(iv)</I></P>
<P style="line-height:18px; margin:0px; padding-left:96px; text-indent:96px; font-size:15.333px" align=justify><I>The Subordinated Indebtedness and any Permitted Refinancing thereof and the Senior Unsecured Note Indebtedness and any Permitted Refinancing thereof.</I></P>
<P style="margin:0px"><BR></P>
<P style="line-height:18.667px; margin-top:0px; margin-bottom:-18.667px; padding-left:180px; text-indent:48px; font-size:16px" align=justify>(i)</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:15.333px; padding-left:180px; text-indent:108px; font-size:15.333px" align=justify><U>Section 6.17(a)</U> of the Credit Agreement is hereby amended to restate <U>clause (i)</U> thereof in its entirety as follows:</P>
<P style="line-height:18px; margin:0px; padding-left:96px; text-indent:48px; font-size:15.333px" align=justify><I>(i) the agreements evidencing or governing Subordinated Indebtedness or any Permitted Refinancing thereof and the agreements evidencing or governing Senior Unsecured Note Indebtedness or any Permitted Refinancing thereof,</I></P>
<P style="margin:0px" align=justify><BR></P>
<P style="line-height:18.667px; margin-top:0px; margin-bottom:-18.667px; padding-left:180px; text-indent:48px; font-size:16px" align=justify>(j)</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:15.333px; padding-left:180px; text-indent:108px; font-size:15.333px" align=justify><U>Section 6.17(b)</U> of the Credit Agreement is hereby amended to restate <U>clause (1)</U> thereof in its entirety as follows:</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:-18px; padding-left:96px; text-indent:48px; font-size:15.333px" align=justify><I>(1)</I></P>
<P style="line-height:normal; margin:0px; padding-left:96px; text-indent:96px; font-size:15.333px" align=justify><I>restrictions imposed by the agreements and instruments governing or evidencing the Subordinated Indebtedness or any Permitted Refinancing thereof and</I> <I>restrictions imposed by the agreements and instruments governing or evidencing the Senior Unsecured Note Indebtedness or any Permitted Refinancing thereof,</I></P>
<P style="margin:0px" align=justify><BR></P>
<P style="line-height:18.667px; margin-top:0px; margin-bottom:-18.667px; padding-left:180px; text-indent:48px; font-size:16px" align=justify>(k)</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:15.333px; padding-left:180px; text-indent:108px; font-size:15.333px" align=justify><U>Section 6.24</U> of the Credit Agreement is hereby amended to restate <U>clause (ii)</U> thereof in its entirety as follows:</P>
<P style="line-height:18px; margin:0px; padding-left:96px; text-indent:48px; font-size:15.333px" align=justify><I>(ii) guaranties of Indebtedness permitted by Section 6.11, provided that only Guarantors shall be permitted to guarantee Subordinated Indebtedness and/or Senior Unsecured Note Indebtedness,</I></P>
<P style="margin:0px" align=justify><BR></P>
<P style="line-height:18.667px; margin-top:0px; margin-bottom:-18.667px; padding-left:180px; text-indent:48px; font-size:16px" align=justify>(l)</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:15.333px; padding-left:180px; text-indent:108px; font-size:15.333px" align=justify><U>Section 6.26.2</U> of the Credit Agreement is hereby amended and restated in its entirety as follows:</P>
<P style="line-height:18px; margin:0px; padding-left:96px; text-indent:48px; font-size:15.333px" align=justify><I>6.26.2. &nbsp;<U>Leverage Ratio</U>. &nbsp;The Borrower will not permit the Leverage Ratio &nbsp;for each fiscal quarter ending (x) prior to the date of a Specified Issuance, to be greater than 3.25 to 1.00 and (y) subsequent to the date of a Specified Issuance, to be greater than 3.50 to 1.00.</I></P>
<P style="margin:0px"><BR></P>
<P style="line-height:18.667px; margin-top:0px; margin-bottom:-18.667px; padding-left:180px; text-indent:48px; font-size:16px" align=justify>(m)</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:15.333px; padding-left:180px; text-indent:108px; font-size:15.333px" align=justify>The Pricing Schedule is hereby amended and restated in its entirety as set forth on <U>Annex A</U> hereto.</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:-18px; text-indent:48px; font-size:15.333px" align=justify>3.</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:15.333px; text-indent:96px; font-size:15.333px" align=justify><U>Conditions of Effectiveness</U>. &nbsp;This Amendment shall become effective as of the date on which the Agent shall have received (i) duly executed originals of this Amendment from the Borrower and the Required Lenders, (ii) such other documents and instruments as are reasonably requested by the Agent in connection with this Amendment, (iii) for the account of each Lender which delivers its executed signature page hereto by such time as is requested by the Agent, an amendment fee equal to 0.05% of such Lender&#146;s Commitment, (iv) payment of the Agent&#146;s fees and expenses (including, to the extent invoiced, fees and expenses of counsel for the Agent) in </P>
<P style="margin-top:0px; margin-bottom:15.333px" align=justify><BR>
<BR></P>
<P style="margin:0px"><BR></P>
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<P style="line-height:18px; margin-top:0px; margin-bottom:15.333px; font-size:15.333px; page-break-before:always" align=justify>connection with the Amendment and (v) a letter executed by the Borrower stating the requested date (which shall be a Business Day) of effectiveness of this Amendment (the date on which all of the foregoing conditions are satisfied, the &#147;<U>Effective Date</U>&#148;). &nbsp;Delivery of an executed counterpart of a signature page of this Amendment by e-mail or facsimile shall be effective as delivery of a manually executed counterpart of this Amendment.</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:-18px; text-indent:48px; font-size:15.333px" align=justify>4.</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:15.333px; text-indent:96px; font-size:15.333px" align=justify><U>Representations and Warranties of the Borrower</U>. &nbsp;The Borrower represents and warrants to the Lenders that, as of the Effective Date and giving effect to this Amendment:</P>
<P style="line-height:18.667px; margin-top:0px; margin-bottom:-18.667px; padding-left:180px; text-indent:48px; font-size:16px" align=justify>(a)</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:15.333px; padding-left:180px; text-indent:108px; font-size:15.333px" align=justify>there exists no Default or Unmatured Default; and</P>
<P style="line-height:18.667px; margin-top:0px; margin-bottom:-18.667px; padding-left:180px; text-indent:48px; font-size:16px" align=justify>(b)</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:15.333px; padding-left:180px; text-indent:108px; font-size:15.333px" align=justify>the representations and warranties contained in <U>Article V</U> of the Credit Agreement are true and correct in all material respects as of the Effective Date except to the extent any such representation or warranty is stated to relate solely to an earlier date, in which case such representation or warranty was true and correct on and as of such earlier date.</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:-18px; text-indent:48px; font-size:15.333px" align=justify>5.</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:15.333px; text-indent:96px; font-size:15.333px" align=justify><U>Reference to and Effect on the Credit Agreement</U>.</P>
<P style="line-height:18.667px; margin-top:0px; margin-bottom:-18.667px; padding-left:180px; text-indent:48px; font-size:16px" align=justify>(a)</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:15.333px; padding-left:180px; text-indent:108px; font-size:15.333px" align=justify>Upon the effectiveness of this Amendment pursuant to <U>Section 3</U> hereof, on and after the Effective Date each reference in the Credit Agreement to &#147;this Agreement,&#148; &#147;hereunder,&#148; &#147;hereof,&#148; &#147;herein&#148; or words of like import and each reference to the Credit Agreement in each other Loan Document shall mean and be a reference to the Credit Agreement as modified hereby.</P>
<P style="line-height:18.667px; margin-top:0px; margin-bottom:-18.667px; padding-left:180px; text-indent:48px; font-size:16px" align=justify>(b)</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:15.333px; padding-left:180px; text-indent:108px; font-size:15.333px" align=justify>Except as specifically waived or amended herein, all of the terms, conditions and covenants of the Credit Agreement and the other Loan Documents shall remain in full force and effect and are hereby ratified and confirmed.</P>
<P style="line-height:18.667px; margin-top:0px; margin-bottom:-18.667px; padding-left:180px; text-indent:48px; font-size:16px" align=justify>(c)</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:15.333px; padding-left:180px; text-indent:108px; font-size:15.333px" align=justify>The execution, delivery and effectiveness of this Amendment shall not, except as expressly provided herein, operate as a waiver of (i) any right, power or remedy of any Lender or the Agent under the Credit Agreement or any of the Loan Documents, or (ii) any Default or Unmatured Default under the Credit Agreement.</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:-18px; text-indent:48px; font-size:15.333px" align=justify>6.</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:15.333px; text-indent:96px; font-size:15.333px" align=justify><B><U>CHOICE OF LAW</U>. &nbsp;THIS AMENDMENT SHALL BE CONSTRUED IN ACCORDANCE WITH THE INTERNAL LAWS (INCLUDING 735 ILCS 105/5-1 ET SEQ. BUT OTHERWISE WITHOUT REGARD TO THE CONFLICT OF LAWS PROVISIONS) OF THE STATE OF ILLINOIS, BUT GIVING EFFECT TO FEDERAL LAWS APPLICABLE TO NATIONAL BANKS.</B></P>
<P style="line-height:18px; margin-top:0px; margin-bottom:-18px; text-indent:48px; font-size:15.333px" align=justify>7.</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:15.333px; text-indent:96px; font-size:15.333px" align=justify><U>Counterparts</U>. &nbsp;This Amendment may be executed in any number of counterparts, each of which when so executed shall be deemed an original and all of which taken together shall constitute one and the same agreement.</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:-18px; text-indent:48px; font-size:15.333px" align=justify>8.</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:15.333px; text-indent:96px; font-size:15.333px" align=justify><U>Headings</U>. &nbsp;Section headings in this Amendment are included herein for convenience of reference only and shall not constitute a part of this Amendment for any other purpose.</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:15.333px; font-size:15.333px" align=center>[Signature Pages Follow]</P>
<P style="margin:0px" align=center><BR>
<BR></P>
<P style="margin:0px"><BR></P>
<P style="margin:0px"><BR></P>
<P style="margin-top:0px; margin-bottom:15.333px; page-break-before:always" align=justify><BR></P>
<P style="line-height:18px; margin-top:0px; margin-bottom:15.333px; text-indent:48px; font-size:15.333px" align=justify>IN WITNESS WHEREOF, the Borrower, the Administrative Agent and the Lenders have executed this Amendment as of the date first above written.</P>
<P style="margin:0px"><BR></P>
<P style="line-height:18px; margin:0px; padding-left:288px; font-size:15.333px"><B>BIO-RAD LABORATORIES, INC.</B>,</P>
<P style="line-height:18px; margin:0px; padding-left:288px; font-size:15.333px">as the Borrower</P>
<P style="margin:0px"><BR></P>
<P style="margin:0px"><BR></P>
<P style="line-height:18px; margin-top:0px; margin-bottom:-18px; padding-left:288px; font-size:15.333px">By:<U> &nbsp;/s/ Ronald W. Hutton</U>______________________<BR>
Name:</P>
<P style="line-height:18px; margin:0px; padding-left:288px; text-indent:48px; font-size:15.333px">Ronald W. Hutton</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:-18px; padding-left:288px; font-size:15.333px">Title:</P>
<P style="line-height:18px; margin:0px; padding-left:288px; text-indent:48px; font-size:15.333px">Treasurer</P>
<P style="margin:0px"><BR></P>
<P style="margin:0px"><BR></P>
<P style="margin:0px"><BR></P>
<P style="margin:0px"><BR></P>
<P style="line-height:18px; margin:0px; padding-left:288px; font-size:15.333px"><B>JPMORGAN CHASE BANK, N.A.</B>,</P>
<P style="line-height:18px; margin:0px; padding-left:288px; font-size:15.333px">Individually as a Lender, as Principal Issuing Lender and as Administrative Agent</P>
<P style="margin:0px"><BR></P>
<P style="margin:0px"><BR></P>
<P style="line-height:18px; margin-top:0px; margin-bottom:-18px; padding-left:288px; font-size:15.333px">By:<U> &nbsp;/s/ Sanjna Daphtary</U>________________________<BR>
Name:</P>
<P style="line-height:18px; margin:0px; padding-left:288px; text-indent:48px; font-size:15.333px">Sanjna Daphtary</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:-18px; padding-left:288px; font-size:15.333px">Title:</P>
<P style="line-height:18px; margin:0px; padding-left:288px; text-indent:48px; font-size:15.333px">Underwriter</P>
<P style="margin:0px"><BR></P>
<P style="margin:0px"><BR></P>
<P style="margin:0px"><BR></P>
<P style="margin:0px"><BR></P>
<P style="line-height:18px; margin:0px; padding-left:288px; font-size:15.333px"><B>WELLS FARGO BANK, N.A.</B>,</P>
<P style="line-height:18px; margin:0px; padding-left:288px; font-size:15.333px">Individually as a Lender and as a Syndication Agent</P>
<P style="margin:0px"><BR></P>
<P style="margin:0px"><BR></P>
<P style="line-height:18px; margin-top:0px; margin-bottom:-18px; padding-left:288px; font-size:15.333px">By:<U> &nbsp;/s/ Michael Jones</U>__________________________<BR>
Name:</P>
<P style="line-height:18px; margin:0px; padding-left:288px; text-indent:48px; font-size:15.333px">Michael Jones</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:-18px; padding-left:288px; font-size:15.333px">Title:</P>
<P style="line-height:18px; margin:0px; padding-left:288px; text-indent:48px; font-size:15.333px">Assistant Vice President</P>
<P style="margin:0px"><BR></P>
<P style="margin:0px"><BR></P>
<P style="margin:0px"><BR></P>
<P style="margin:0px"><BR></P>
<P style="line-height:18px; margin:0px; padding-left:288px; font-size:15.333px"><B>UNION BANK OF CALIFORNIA, N.A.</B>,</P>
<P style="line-height:18px; margin:0px; padding-left:288px; font-size:15.333px">Individually as a Lender and as a Syndication Agent</P>
<P style="margin:0px"><BR></P>
<P style="margin:0px"><BR></P>
<P style="line-height:18px; margin-top:0px; margin-bottom:-18px; padding-left:288px; font-size:15.333px">By:<U> &nbsp;/s/ Peter Sitov</U>____________________________<BR>
Name:</P>
<P style="line-height:18px; margin:0px; padding-left:288px; text-indent:48px; font-size:15.333px">Peter Sitov</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:-18px; padding-left:288px; font-size:15.333px">Title:</P>
<P style="line-height:18px; margin:0px; padding-left:288px; text-indent:48px; font-size:15.333px">Senior Vice President</P>
<P style="margin:0px"><BR></P>
<P style="margin:0px"><BR></P>
<P style="margin:0px"><BR>
<BR></P>
<P style="margin:0px"><BR></P>
<P style="margin:0px"><BR></P>
<P style="margin:0px; page-break-before:always"><BR></P>
<P style="margin:0px"><BR></P>
<P style="line-height:18px; margin:0px; padding-left:288px; font-size:15.333px"><B>ABN AMRO BANK N.V.</B>,</P>
<P style="line-height:18px; margin:0px; padding-left:288px; font-size:15.333px">Individually as a Lender and as a Documentation Agent</P>
<P style="margin:0px"><BR></P>
<P style="margin:0px"><BR></P>
<P style="line-height:18px; margin:0px; padding-left:288px; font-size:15.333px">By:<U> &nbsp;/s/ Alexander M. Blodi</U>_____________________</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:-18px; padding-left:288px; font-size:15.333px">Name:</P>
<P style="line-height:18px; margin:0px; padding-left:288px; text-indent:48px; font-size:15.333px">Alexander M. Blodi</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:-18px; padding-left:288px; font-size:15.333px">Title:</P>
<P style="line-height:18px; margin:0px; padding-left:288px; text-indent:48px; font-size:15.333px">Managing Director</P>
<P style="margin:0px"><BR></P>
<P style="margin:0px"><BR></P>
<P style="line-height:18px; margin:0px; padding-left:288px; font-size:15.333px">By:<U> &nbsp;/s/ Michele Costello</U>_______________________</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:-18px; padding-left:288px; font-size:15.333px">Name:</P>
<P style="line-height:18px; margin:0px; padding-left:288px; text-indent:48px; font-size:15.333px">Michele Costello</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:-18px; padding-left:288px; font-size:15.333px">Title:</P>
<P style="line-height:18px; margin:0px; padding-left:288px; text-indent:48px; font-size:15.333px">Director</P>
<P style="margin:0px"><BR></P>
<P style="margin:0px"><BR></P>
<P style="margin:0px"><BR></P>
<P style="margin:0px"><BR></P>
<P style="line-height:18px; margin:0px; padding-left:288px; font-size:15.333px"><B>BNP PARIBAS</B>,</P>
<P style="line-height:18px; margin:0px; padding-left:288px; font-size:15.333px">Individually as a Lender and as a Documentation Agent</P>
<P style="margin:0px"><BR></P>
<P style="margin:0px"><BR></P>
<P style="line-height:18px; margin-top:0px; margin-bottom:-18px; padding-left:288px; font-size:15.333px">By:<U> &nbsp;/s/ Katherine Wolfe</U>________________________<BR>
Name:</P>
<P style="line-height:18px; margin:0px; padding-left:288px; text-indent:48px; font-size:15.333px">Katherine Wolfe</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:-18px; padding-left:288px; font-size:15.333px">Title:</P>
<P style="line-height:18px; margin:0px; padding-left:288px; text-indent:48px; font-size:15.333px">Managing Director</P>
<P style="margin:0px"><BR></P>
<P style="margin:0px"><BR></P>
<P style="line-height:18px; margin:0px; padding-left:288px; font-size:15.333px">By:<U> &nbsp;/s/ Sandy Bertram</U>_________________________</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:-18px; padding-left:288px; font-size:15.333px">Name:</P>
<P style="line-height:18px; margin:0px; padding-left:288px; text-indent:48px; font-size:15.333px">Sandy Bertram</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:-18px; padding-left:288px; font-size:15.333px">Title:</P>
<P style="line-height:18px; margin:0px; padding-left:288px; text-indent:48px; font-size:15.333px">Vice President</P>
<P style="margin:0px"><BR></P>
<P style="margin:0px"><BR></P>
<P style="margin:0px"><BR></P>
<P style="line-height:18px; margin:0px; padding-left:288px; font-size:15.333px"><B>COMERICA BANK</B>,</P>
<P style="line-height:18px; margin:0px; padding-left:288px; font-size:15.333px">Individually as a Lender</P>
<P style="margin:0px"><BR></P>
<P style="margin:0px"><BR></P>
<P style="line-height:18px; margin-top:0px; margin-bottom:-18px; padding-left:288px; font-size:15.333px">By:<U> &nbsp;/s/ Steve Clear</U>____________________________<BR>
Name:</P>
<P style="line-height:18px; margin:0px; padding-left:288px; text-indent:48px; font-size:15.333px">Steve Clear</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:-18px; padding-left:288px; font-size:15.333px">Title:</P>
<P style="line-height:18px; margin:0px; padding-left:288px; text-indent:48px; font-size:15.333px">AVP</P>
<P style="margin:0px"><BR></P>
<P style="margin:0px"><BR></P>
<P style="margin:0px"><BR></P>
<P style="margin:0px"><BR></P>
<P style="line-height:18px; margin:0px; padding-left:288px; font-size:15.333px"><B>U.S. BANK NATIONAL ASSOCIATION</B>,</P>
<P style="line-height:18px; margin:0px; padding-left:288px; font-size:15.333px">Individually as a Lender</P>
<P style="margin:0px"><BR></P>
<P style="margin:0px"><BR>
<BR></P>
<P style="margin:0px"><BR></P>
<P style="margin:0px"><BR></P>
<P style="margin:0px; page-break-before:always"><BR></P>
<P style="line-height:18px; margin-top:0px; margin-bottom:-18px; padding-left:288px; font-size:15.333px">By:<U> &nbsp;/s/ Conan Schleicher</U>_______________________<BR>
Name:</P>
<P style="line-height:18px; margin:0px; padding-left:288px; text-indent:48px; font-size:15.333px">Conan Schleicher</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:-18px; padding-left:288px; font-size:15.333px">Title:</P>
<P style="line-height:18px; margin:0px; padding-left:288px; text-indent:48px; font-size:15.333px">Vice President</P>
<P style="margin:0px"><BR></P>
<P style="margin:0px"><BR></P>
<P style="margin:0px"><BR></P>
<P style="margin:0px"><BR></P>
<P style="line-height:18px; margin:0px; padding-left:288px; font-size:15.333px"><B>THE NORTHERN TRUST COMPANY</B>,</P>
<P style="line-height:18px; margin:0px; padding-left:288px; font-size:15.333px">Individually as a Lender</P>
<P style="margin:0px"><BR></P>
<P style="margin:0px"><BR></P>
<P style="line-height:18px; margin-top:0px; margin-bottom:-18px; padding-left:288px; font-size:15.333px">By:<U> &nbsp;/s/ John E. Burda</U>__________________________<BR>
Name:</P>
<P style="line-height:18px; margin:0px; padding-left:288px; text-indent:48px; font-size:15.333px">John E. Burda</P>
<P style="line-height:18px; margin-top:0px; margin-bottom:-18px; padding-left:288px; font-size:15.333px">Title:</P>
<P style="line-height:18px; margin:0px; padding-left:288px; text-indent:48px; font-size:15.333px">Vice President</P>
<P style="margin:0px"><BR></P>
<P style="margin:0px"><BR></P>
<P style="margin:0px"><BR>
<BR></P>
<P style="margin:0px"><BR></P>
<P style="margin:0px"><BR></P>
<P style="line-height:18px; margin:0px; font-size:15.333px; page-break-before:always" align=center>ANNEX A</P>
<P style="margin:0px" align=center><BR></P>
<P style="line-height:17.333px; margin-top:0px; margin-bottom:14.667px; font-size:14.667px" align=center>PRICING SCHEDULE</P>
<TABLE style="font-size:13.333px" cellspacing=0><TR><TD width=135.2></TD><TD width=80></TD><TD width=80></TD><TD width=80></TD><TD width=88></TD><TD width=80></TD><TD width=88></TD></TR>
<TR><TD style="border:1px solid #000000" valign=top width=135.2><P style="line-height:17.333px; margin:0px; font-size:14.667px" align=center><B>Applicable </B></P>
<P style="line-height:17.333px; margin:0px; font-size:14.667px" align=center><B>Margin</B></P>
</TD><TD style="border-top:1px solid #000000; border-right:1px solid #000000; border-bottom:1px solid #000000" valign=top width=80><P style="line-height:17.333px; margin:0px; font-size:14.667px" align=center><B>Level I Status</B></P>
</TD><TD style="border-top:1px solid #000000; border-right:1px solid #000000; border-bottom:1px solid #000000" valign=top width=80><P style="line-height:17.333px; margin:0px; font-size:14.667px" align=center><B>Level II Status</B></P>
</TD><TD style="border-top:1px solid #000000; border-right:1px solid #000000; border-bottom:1px solid #000000" valign=top width=80><P style="line-height:17.333px; margin:0px; font-size:14.667px" align=center><B>Level III Status</B></P>
</TD><TD style="border-top:1px solid #000000; border-right:1px solid #000000; border-bottom:1px solid #000000" valign=top width=88><P style="line-height:17.333px; margin:0px; font-size:14.667px" align=center><B>Level IV Status</B></P>
</TD><TD style="border-top:1px solid #000000; border-right:1px solid #000000; border-bottom:1px solid #000000" valign=top width=80><P style="line-height:17.333px; margin:0px; font-size:14.667px" align=center><B>Level V Status</B></P>
</TD><TD style="border-top:1px solid #000000; border-right:1px solid #000000; border-bottom:1px solid #000000" valign=top width=88><P style="line-height:17.333px; margin:0px; font-size:14.667px" align=center><B>Level VI Status</B></P>
</TD></TR>
<TR><TD style="border-left:1px solid #000000; border-right:1px solid #000000; border-bottom:1px solid #000000" valign=top width=135.2><P style="line-height:17.333px; margin:0px; font-size:14.667px" align=center>Eurocurrency Rate</P>
</TD><TD style="border-right:1px solid #000000; border-bottom:1px solid #000000" valign=top width=80><P style="line-height:17.333px; margin:0px; font-size:14.667px" align=center>0.750%</P>
</TD><TD style="border-right:1px solid #000000; border-bottom:1px solid #000000" valign=top width=80><P style="line-height:17.333px; margin:0px; font-size:14.667px" align=center>0.875%</P>
</TD><TD style="border-right:1px solid #000000; border-bottom:1px solid #000000" valign=top width=80><P style="line-height:17.333px; margin:0px; font-size:14.667px" align=center>1.000%</P>
</TD><TD style="border-right:1px solid #000000; border-bottom:1px solid #000000" valign=top width=88><P style="line-height:17.333px; margin:0px; font-size:14.667px" align=center>1.125%</P>
</TD><TD style="border-right:1px solid #000000; border-bottom:1px solid #000000" valign=top width=80><P style="line-height:17.333px; margin:0px; font-size:14.667px" align=center>1.250%</P>
</TD><TD style="border-right:1px solid #000000; border-bottom:1px solid #000000" valign=top width=88><P style="line-height:17.333px; margin:0px; font-size:14.667px" align=center>1.500%</P>
</TD></TR>
<TR><TD style="border-left:1px solid #000000; border-right:1px solid #000000; border-bottom:1px solid #000000" valign=top width=135.2><P style="line-height:17.333px; margin:0px; font-size:14.667px" align=center>Floating Rate</P>
</TD><TD style="border-right:1px solid #000000; border-bottom:1px solid #000000" valign=top width=80><P style="line-height:17.333px; margin:0px; font-size:14.667px" align=center>0.000%</P>
</TD><TD style="border-right:1px solid #000000; border-bottom:1px solid #000000" valign=top width=80><P style="line-height:17.333px; margin:0px; font-size:14.667px" align=center>0.000%</P>
</TD><TD style="border-right:1px solid #000000; border-bottom:1px solid #000000" valign=top width=80><P style="line-height:17.333px; margin:0px; font-size:14.667px" align=center>0.000%</P>
</TD><TD style="border-right:1px solid #000000; border-bottom:1px solid #000000" valign=top width=88><P style="line-height:17.333px; margin:0px; font-size:14.667px" align=center>0.000%</P>
</TD><TD style="border-right:1px solid #000000; border-bottom:1px solid #000000" valign=top width=80><P style="line-height:17.333px; margin:0px; font-size:14.667px" align=center>0.250%</P>
</TD><TD style="border-right:1px solid #000000; border-bottom:1px solid #000000" valign=top width=88><P style="line-height:17.333px; margin:0px; font-size:14.667px" align=center>0.500%</P>
</TD></TR>
<TR><TD style="border-bottom:1px solid #000000" valign=top width=135.2><P style="font-size:2pt">&nbsp;</P></TD><TD style="border-bottom:1px solid #000000" valign=top width=80><P style="font-size:2pt">&nbsp;</P></TD><TD style="border-bottom:1px solid #000000" valign=top width=80><P style="font-size:2pt">&nbsp;</P></TD><TD style="border-bottom:1px solid #000000" valign=top width=80><P style="font-size:2pt">&nbsp;</P></TD><TD style="border-right:1px solid #000000; border-bottom:1px solid #000000" valign=top width=88><P style="font-size:2pt">&nbsp;</P></TD><TD style="border-right:1px solid #000000; border-bottom:1px solid #000000" valign=top width=80><P style="font-size:2pt">&nbsp;</P></TD><TD style="border-right:1px solid #000000; border-bottom:1px solid #000000" valign=top width=88><P style="font-size:2pt">&nbsp;</P></TD></TR>
<TR><TD style="border-left:1px solid #000000; border-right:1px solid #000000; border-bottom:1px solid #000000" valign=top width=135.2><P style="line-height:17.333px; margin:0px; font-size:14.667px" align=center><B>Applicable Fee Rate</B></P>
</TD><TD style="border-right:1px solid #000000; border-bottom:1px solid #000000" valign=top width=80><P style="line-height:17.333px; margin:0px; font-size:14.667px" align=center><B>Level I Status</B></P>
</TD><TD style="border-right:1px solid #000000; border-bottom:1px solid #000000" valign=top width=80><P style="line-height:17.333px; margin:0px; font-size:14.667px" align=center><B>Level II Status</B></P>
</TD><TD style="border-right:1px solid #000000; border-bottom:1px solid #000000" valign=top width=80><P style="line-height:17.333px; margin:0px; font-size:14.667px" align=center><B>Level III Status</B></P>
</TD><TD style="border-right:1px solid #000000; border-bottom:1px solid #000000" valign=top width=88><P style="line-height:17.333px; margin:0px; font-size:14.667px" align=center><B>Level IV Status</B></P>
</TD><TD style="border-right:1px solid #000000; border-bottom:1px solid #000000" valign=top width=80><P style="line-height:17.333px; margin:0px; font-family:Times New Roman Bold; font-size:14.667px" align=center><FONT FACE="Times New Roman Bold"><B>Level V Status</B></FONT></P>
</TD><TD style="border-right:1px solid #000000; border-bottom:1px solid #000000" valign=top width=88><P style="line-height:17.333px; margin:0px; font-family:Times New Roman Bold; font-size:14.667px" align=center><B>Level VI Status</B></P>
</TD></TR>
<TR><TD style="border-left:1px solid #000000; border-right:1px solid #000000; border-bottom:1px solid #000000" valign=top width=135.2><P style="line-height:17.333px; margin:0px; font-size:14.667px" align=center><FONT FACE="Times New Roman">Commitment Fee</FONT></P>
</TD><TD style="border-right:1px solid #000000; border-bottom:1px solid #000000" valign=top width=80><P style="line-height:17.333px; margin:0px; font-size:14.667px" align=center>0.150%</P>
</TD><TD style="border-right:1px solid #000000; border-bottom:1px solid #000000" valign=top width=80><P style="line-height:17.333px; margin:0px; font-size:14.667px" align=center>0.175%</P>
</TD><TD style="border-right:1px solid #000000; border-bottom:1px solid #000000" valign=top width=80><P style="line-height:17.333px; margin:0px; font-size:14.667px" align=center>0.200%</P>
</TD><TD style="border-right:1px solid #000000; border-bottom:1px solid #000000" valign=top width=88><P style="line-height:17.333px; margin:0px; font-size:14.667px" align=center>0.225%</P>
</TD><TD style="border-right:1px solid #000000; border-bottom:1px solid #000000" valign=top width=80><P style="line-height:17.333px; margin:0px; font-size:14.667px" align=center>0.250%</P>
</TD><TD style="border-right:1px solid #000000; border-bottom:1px solid #000000" valign=top width=88><P style="line-height:17.333px; margin:0px; font-size:14.667px" align=center>0.300%</P>
</TD></TR>
<TR><TD style="border-left:1px solid #000000; border-right:1px solid #000000; border-bottom:1px solid #000000" valign=top width=135.2><P style="line-height:17.333px; margin:0px; font-size:14.667px" align=center>Letter of Credit Fee</P>
</TD><TD style="border-right:1px solid #000000; border-bottom:1px solid #000000" valign=top width=80><P style="line-height:17.333px; margin:0px; font-size:14.667px" align=center>0.625%</P>
</TD><TD style="border-right:1px solid #000000; border-bottom:1px solid #000000" valign=top width=80><P style="line-height:17.333px; margin:0px; font-size:14.667px" align=center>0.750%</P>
</TD><TD style="border-right:1px solid #000000; border-bottom:1px solid #000000" valign=top width=80><P style="line-height:17.333px; margin:0px; font-size:14.667px" align=center>0.875%</P>
</TD><TD style="border-right:1px solid #000000; border-bottom:1px solid #000000" valign=top width=88><P style="line-height:17.333px; margin:0px; font-size:14.667px" align=center>1.000%</P>
</TD><TD style="border-right:1px solid #000000; border-bottom:1px solid #000000" valign=top width=80><P style="line-height:17.333px; margin:0px; font-size:14.667px" align=center>1.125%</P>
</TD><TD style="border-right:1px solid #000000; border-bottom:1px solid #000000" valign=top width=88><P style="line-height:17.333px; margin:0px; font-size:14.667px" align=center>1.250%</P>
</TD></TR>
<TR><TD valign=top width=135.2><P style="font-size:2pt">&nbsp;</P></TD><TD valign=top width=80><P style="font-size:2pt">&nbsp;</P></TD><TD valign=top width=80><P style="font-size:2pt">&nbsp;</P></TD><TD valign=top width=80><P style="font-size:2pt">&nbsp;</P></TD><TD valign=top width=88><P style="font-size:2pt">&nbsp;</P></TD><TD valign=top width=80><P style="font-size:2pt">&nbsp;</P></TD><TD valign=top width=88><P style="font-size:2pt">&nbsp;</P></TD></TR>
</TABLE>
<P style="line-height:17.333px; margin-top:0px; margin-bottom:14.667px; text-indent:96px; font-size:14.667px" align=justify>For the purposes of this Schedule, the following terms have the following meanings, subject to the final paragraph of this Schedule:</P>
<P style="line-height:17.333px; margin-top:0px; margin-bottom:14.667px; text-indent:96px; font-size:14.667px" align=justify>&#147;Financials&#148; means the annual or quarterly financial statements of the Borrower delivered pursuant to <U>Section 6.1(i)</U> or <U>(ii)</U>.</P>
<P style="line-height:17.333px; margin-top:0px; margin-bottom:14.667px; text-indent:96px; font-size:14.667px" align=justify>&#147;Level I Status&#148; exists at any date if, as of the last day of the fiscal quarter of the Borrower referred to in the most recent Financials, the Leverage Ratio is less than or equal to 1.25 to 1.00.</P>
<P style="line-height:17.333px; margin-top:0px; margin-bottom:14.667px; text-indent:96px; font-size:14.667px" align=justify>&#147;Level II Status&#148; exists at any date if, as of the last day of the fiscal quarter of the Borrower referred to in the most recent Financials, (i) the Borrower has not qualified for Level I Status and (ii) the Leverage Ratio is less than or equal to 1.75 to 1.00.</P>
<P style="line-height:17.333px; margin-top:0px; margin-bottom:14.667px; text-indent:96px; font-size:14.667px" align=justify>&#147;Level III Status&#148; exists at any date if, as of the last day of the fiscal quarter of the Borrower referred to in the most recent Financials, (i) the Borrower has not qualified for Level I Status or Level II Status and (ii) the Leverage Ratio is less than or equal to 2.25 to 1.00.</P>
<P style="line-height:17.333px; margin-top:0px; margin-bottom:14.667px; text-indent:96px; font-size:14.667px" align=justify>&#147;Level IV Status&#148; exists at any date if, as of the last day of the fiscal quarter of the Borrower referred to in the most recent Financials, (i) the Borrower has not qualified for Level I Status, Level II Status or Level III Status and (ii) the Leverage Ratio is less than or equal to 2.75 to 1.00.</P>
<P style="line-height:17.333px; margin-top:0px; margin-bottom:14.667px; text-indent:96px; font-size:14.667px" align=justify>&#147;Level V Status&#148; exists at any date if, as of the last day of the fiscal quarter of the Borrower referred to in the most recent Financials, (i) the Borrower has not qualified for Level I Status, Level II Status, Level III Status or Level IV Status and (ii) the Leverage Ratio is less than or equal to 3.25 to 1.00.</P>
<P style="line-height:17.333px; margin-top:0px; margin-bottom:14.667px; text-indent:96px; font-size:14.667px" align=justify>&#147;Level VI Status&#148; exists at any date if the Borrower has not qualified for Level I Status, Level II Status, Level III Status, Level IV Status or Level V Status.</P>
<P style="line-height:17.333px; margin-top:0px; margin-bottom:14.667px; text-indent:96px; font-size:14.667px" align=justify>&#147;Status&#148; means either Level I Status, Level II Status, Level III Status, Level IV Status, Level V Status or Level VI Status.</P>
<P style="line-height:17.333px; margin-top:0px; margin-bottom:14.667px; text-indent:96px; font-size:14.667px" align=justify>The Applicable Margin and Applicable Fee Rate shall be determined in accordance with the foregoing table based on the Borrower&#146;s Status as reflected in the then most recent Financials. &nbsp;Adjustments, if any, to the Applicable Margin or Applicable Fee Rate shall be effective five (5) Business Days after the Agent has received the applicable Financials. &nbsp;If the Borrower fails to deliver the Financials to the Agent at the time required pursuant to <U>Section 6.1</U>, then the Applicable Margin and Applicable Fee Rate shall be the highest Applicable Margin and Applicable Fee Rate set forth in the foregoing table until five (5) Business Days after such Financials are so delivered.</P>
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<DOCUMENT>
<TYPE>EX-99
<SEQUENCE>3
<FILENAME>exhibit991.htm
<DESCRIPTION>EXHIBIT 99.1
<TEXT>
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<HEAD>
<TITLE>PART 1 &#8211; FINANCIAL INFORMATION</TITLE>
<META NAME="author" CONTENT="Stephanie Trudrung">
<META NAME="date" CONTENT="11/06/2008">
</HEAD>
<BODY style="line-height:12pt; font-family:Times New Roman; font-size:10pt; color:#000000">
<DIV style="width:604.8px"><P style="line-height:18.667px; margin:0px; font-size:16px" align=right><B><U>Exhibit 99.1</U></B></P>
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<TABLE style="font-size:13.333px" cellspacing=0><TR><TD width=619.2></TD></TR>
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<P style="line-height:17.333px; margin:0px; font-family:Arial; font-size:14.667px" align=center><FONT FACE="Arial"><B>BIO-RAD ANNOUNCES PRIVATE OFFERING OF $250 MILLION </B></FONT></P>
<P style="line-height:17.333px; margin:0px; font-family:Arial; font-size:14.667px" align=center><B>OF SENIOR SUBORDINATED NOTES</B></P>
<P style="line-height:21.333px; margin:0px"><BR></P>
<P style="line-height:21.333px; margin:0px"><BR></P>
<P style="line-height:21.333px; margin:0px; font-family:Arial; font-size:14.667px">HERCULES, CA &#150; May 19, 2009 &#150; Bio-Rad Laboratories, Inc. (NYSE: BIO and BIOb), a multinational manufacturer and distributor of life science research and clinical diagnostics products, announced today that it intends to commence an offering, subject to market and other conditions, of $250 million aggregate principal amount of senior subordinated notes in a private offering. The Company intends to use the proceeds for working capital and general corporate purposes, which may include acquisitions.</P>
<P style="line-height:21.333px; margin:0px"><BR></P>
<P style="line-height:21.333px; margin:0px; font-family:Arial; font-size:14.667px">The new senior subordinated notes have not been registered under the Securities Act of 1933, as amended, or applicable state securities laws, and will be offered only to qualified institutional buyers in reliance on Rule 144A and in offshore transactions pursuant to Regulation S under the Securities Act of 1933, as amended. Unless so registered, the new senior subordinated notes may not be offered or sold in the United States except pursuant to an exemption from the registration requirements of the Securities Act and applicable state securities laws. </P>
<P style="line-height:21.333px; margin:0px"><BR></P>
<P style="line-height:21.333px; margin:0px; font-family:Arial; font-size:14.667px">This press release shall not constitute an offer to sell or the solicitation of an offer to buy these securities, nor shall there be any sale of these securities in any state in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such state.</P>
<P style="line-height:21.333px; margin:0px"><BR></P>
<P style="line-height:17.333px; margin:0px; font-family:Arial; font-size:14.667px">This release contains certain forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 and Section 21E of the Securities Exchange Act of 1934. Forward-looking statements generally can be identified by the use of forward-looking terminology such as, &quot;believe,&quot; &quot;expect,&quot; &quot;may,&quot; &quot;will,&quot; &quot;intend,&quot; &quot;estimate,&quot; &quot;continue,&quot; or similar expressions or the negative of those terms or expressions. Such statements involve risks and uncertainties, which could cause actual results to vary materially from those expressed in or indicated by the forward-looking statements. For further information regarding the Company's risks and uncertainties, please refer to the &quot;Risk Factors&quot; in the Company's public reports filed with the Securities and Exchange Commission, including the Company's Annual Report on Form 10-K for the fis
cal year ended December 31, 2008, as </P>
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<P style="line-height:17.333px; margin:0px; font-family:Arial; font-size:14.667px" align=center>(more)</P>
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<TABLE style="font-size:13.333px" cellspacing=0><TR><TD width=619.2></TD></TR>
<TR><TD valign=top width=619.2><P style="margin:0px" align=center><BR></P>
<P style="line-height:17.333px; margin:0px; font-family:Arial; font-size:14.667px">Bio-Rad Announces Private Offering&#133;</P>
<P style="line-height:17.333px; margin:0px; font-family:Arial; font-size:14.667px">Page 2</P>
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<P style="line-height:17.333px; margin:0px; font-family:Arial; font-size:14.667px">updated by subsequent Quarterly Reports on Form 10-Q and Current Reports on Form 8-K. The Company cautions you not to place undue reliance on forward-looking statements, which reflect an analysis only and speak only as of the date hereof. Bio-Rad Laboratories, Inc., disclaims any obligation to update these forward-looking statements.</P>
<P style="margin:0px"><BR></P>
<P style="line-height:21.333px; margin:0px"><BR></P>
<P style="line-height:21.333px; margin:0px; font-family:Arial; font-size:14.667px">For more information contact:</P>
<P style="line-height:21.333px; margin:0px; font-family:Arial; font-size:14.667px">Christine Tsingos, Vice President and Chief Financial Officer, or</P>
<P style="line-height:21.333px; margin:0px; font-family:Arial; font-size:14.667px">Ron Hutton, Treasurer</P>
<P style="line-height:21.333px; margin:0px; font-family:Arial; font-size:14.667px">Bio-Rad Laboratories, Inc.</P>
<P style="line-height:21.333px; margin:0px; font-family:Arial; font-size:14.667px">Phone: 510-724-7000</P>
<P style="line-height:21.333px; margin:0px; font-family:Arial; font-size:14.667px">Email: investor_relations@bio-rad.com</P>
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</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99
<SEQUENCE>4
<FILENAME>exhibit992.htm
<DESCRIPTION>EXHIBIT 99.2
<TEXT>
<!doctype html public "-//IETF//DTD HTML//EN">
<HTML>
<HEAD>
<TITLE>PART 1 &#8211; FINANCIAL INFORMATION</TITLE>
<META NAME="author" CONTENT="Stephanie Trudrung">
<META NAME="date" CONTENT="11/06/2008">
</HEAD>
<BODY style="line-height:12pt; font-family:Times New Roman; font-size:10pt; color:#000000">
<DIV style="width:604.8px"><P style="line-height:18.667px; margin:0px; font-size:16px" align=right><B><U>Exhibit 99.2</U></B></P>
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<TR><TD valign=top width=619.2><P style="margin:0px"><BR></P>
<P style="line-height:21.733px; margin-top:6.133px; margin-bottom:6.133px; font-family:Arial; font-size:14.667px"><FONT FACE="Arial">FOR IMMEDIATE RELEASE</FONT></P>
<P style="margin:0px"><BR></P>
<P style="line-height:17.333px; margin:0px; font-family:Arial; font-size:14.667px" align=center>Bio-Rad Announces Pricing of Private Offering of $300 Million of</P>
<P style="line-height:17.333px; margin:0px; font-family:Arial; font-size:14.667px" align=center>Senior Subordinated Notes</P>
<P style="line-height:21.333px; margin:0px"><BR></P>
<P style="line-height:21.333px; margin:0px; font-family:Arial">HERCULES, CA &#150; May 19, 2009 &#150; Bio-Rad Laboratories, Inc. (NYSE: BIO and BIOb), a multinational manufacturer and distributor of life science research and clinical diagnostics products, announced that it has agreed to sell $300 million aggregate principal amount of its 8.00% Senior Subordinated Notes due 2016 in a private offering. The Company intends to close the transaction on May 26, 2009. </P>
<P style="line-height:21.333px; margin:0px"><BR></P>
<P style="line-height:21.333px; margin:0px; font-family:Arial">The Company intends to use the proceeds for working capital and general corporate purposes, which may include acquisitions.</P>
<P style="line-height:21.333px; margin:0px"><BR></P>
<P style="line-height:21.333px; margin:0px; font-family:Arial">The new Senior Subordinated Notes have not been registered under the Securities Act of 1933, as amended, or applicable state securities laws, and will be offered only to qualified institutional buyers in reliance on Rule 144A and in offshore transactions pursuant to Regulation S under the Securities Act of 1933, as amended. Unless so registered, the new Senior Subordinated Notes may not be offered or sold in the United States except pursuant to an exemption from the registration requirements of the Securities Act and applicable state securities laws. </P>
<P style="line-height:21.333px; margin:0px"><BR></P>
<P style="line-height:21.333px; margin:0px; font-family:Arial">This press release shall not constitute an offer to sell or the solicitation of an offer to buy these securities, nor shall there be any sale of these securities in any state in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such state.</P>
<P style="line-height:21.333px; margin:0px"><BR></P>
<P style="margin:0px; font-family:Arial"><I>This release contains certain forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 and Section 21E of the Securities Exchange Act of 1934. Forward-looking statements generally can be identified by the use of forward-looking terminology such as, &quot;believe,&quot; &quot;expect,&quot; &quot;may,&quot; &quot;will,&quot; &quot;intend,&quot; &quot;estimate,&quot; &quot;continue,&quot; or similar expressions or the negative of those terms or expressions. Such statements involve risks and uncertainties, which could cause actual results to vary materially from those expressed in or indicated by the forward-looking statements. For further information regarding the Company's risks and uncertainties, please refer to the &quot;Risk Factors&quot; in the Company's public reports filed with the Securities and Exchange Commission, including the Company's Annual Report on Form 10-K for the fiscal year ended December 31, 2008, as up
dated by subsequent Quarterly Reports on Form 10-Q and Current Reports on Form 8-K. The Company cautions you not to place undue reliance on forward-looking statements, which reflect an analysis only and speak only as of the date hereof. Bio-Rad Laboratories, Inc., disclaims any obligation to update these forward-looking statements.</I></P>
<P style="line-height:21.333px; margin:0px"><BR></P>
<P style="margin:0px; font-family:Arial">For more information contact:</P>
<P style="margin:0px; font-family:Arial">Christine Tsingos, Vice President and Chief Financial Officer, or</P>
<P style="margin:0px; font-family:Arial">Ron Hutton, Treasurer</P>
<P style="margin:0px; font-family:Helvetica 55 Roman"><FONT FACE="Helvetica 55 Roman">Bio-Rad Laboratories, Inc.</FONT></P>
<P style="margin:0px; font-family:Helvetica 55 Roman">Phone: 510-724-7000</P>
<P style="margin:0px; font-family:Helvetica 55 Roman">Email: investor_relations@bio-rad.com</P>
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