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4. Intangible Assets, Goodwill and Other (Tables) | 3 Months Ended
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Mar. 31, 2016
Goodwill and Intangible Assets Disclosure [Abstract] |
Changes to goodwill by segment | Changes to goodwill by segment were as follows (in millions):
| Life Science |  | Clinical Diagnostics |  | Total
Balances as of January 1, 2016: |  |  |  |  |
Goodwill | $ | 207.2 |  |  | $ | 316.9 |  |  | $ | 524.1 |
Accumulated impairment losses | (27.2 | ) |  | (1.0 | ) |  | (28.2 | )
Goodwill, net | 180.0 |  |  | 315.9 |  |  | 495.9 |
Acquisitions | 2.8 |  |  | — |  |  | 2.8 |
Currency fluctuations | 0.5 |  |  | 10.4 |  |  | 10.9 |
Balances as of March 31, 2016: |  |  |  |  |
Goodwill | 210.5 |  |  | 327.3 |  |  | 537.8 |
Accumulated impairment losses | (27.2 | ) |  | (1.0 | ) |  | (28.2 | )
Goodwill, net | $ | 183.3 |  |  | $ | 326.3 |  |  | $ | 509.6 |
Schedule of identifiable purchased intangible assets with definite lives | Information regarding our identifiable purchased intangible assets with definite and indefinite lives is as follows (in millions):
| March 31, 2016
| Average Remaining Life (years) |  | Purchase Price |  | Accumulated Amortization |  | Net Carrying Amount
Customer relationships/lists | 2-9 |  | $ | 88.3 |  |  | $ | (50.4 | ) |  | $ | 37.9 |
Know how | 1-10 |  | 187.6 |  |  | (129.8 | ) |  | 57.8 |
Developed product technology | 3-13 |  | 134.9 |  |  | (52.1 | ) |  | 82.8 |
Licenses | 3-10 |  | 39.6 |  |  | (29.2 | ) |  | 10.4 |
Tradenames | 5-8 |  | 3.6 |  |  | (2.5 | ) |  | 1.1 |
Covenants not to compete | 3-10 |  | 7.8 |  |  | (1.9 | ) |  | 5.9 |
Total definite-lived intangible assets |  |  | 461.8 |  |  | (265.9 | ) |  | 195.9 |
In-process research and development |  |  | 46.4 |  |  | — |  |  | 46.4 |
Total purchased intangible assets |  |  | $ | 508.2 |  |  | $ | (265.9 | ) |  | $ | 242.3 |
| December 31, 2015
| Average Remaining Life (years) |  | Purchase Price |  | Accumulated Amortization |  | Net Carrying Amount
Customer relationships/lists | 2-10 |  | $ | 84.7 |  |  | $ | (46.8 | ) |  | $ | 37.9 |
Know how | 1-10 |  | 184.0 |  |  | (121.6 | ) |  | 62.4 |
Developed product technology | 4-12 |  | 101.3 |  |  | (48.9 | ) |  | 52.4 |
Licenses | 3-10 |  | 39.2 |  |  | (28.5 | ) |  | 10.7 |
Tradenames | 5-9 |  | 3.5 |  |  | (2.4 | ) |  | 1.1 |
Covenants not to compete | 3-7 |  | 4.8 |  |  | (1.7 | ) |  | 3.1 |
Total definite-lived intangible assets |  |  | 417.5 |  |  | (249.9 | ) |  | 167.6 |
In-process research and development |  |  | 46.4 |  |  | — |  |  | 46.4 |
Total purchased intangible assets |  |  | $ | 463.9 |  |  | $ | (249.9 | ) |  | $ | 214.0 |
Finite-lived Intangible Assets Amortization Expense [Table Text Block] | Amortization expense related to purchased intangible assets is as follows (in millions):
| Three Months Ended |
| March 31, |
| 2016 |  | 2015 |
Amortization expense | $ | 9.4 |  |  | $ | 9.2 |  |

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- Definition Tabular disclosure of the characteristics, including initial carrying value, residual amount, weighted average useful life, of finite-lived intangible assets acquired during the period by major class. A major class is composed of intangible assets that can be grouped together because they are similar, either by nature or by their use in the operations of the company. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 350 -SubTopic 30 -Section 50 -Paragraph 1 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=26713463&loc=d3e16265-109275 + Details
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