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4. Goodwill and other Purchased Intangible Assets Intangible Assets, Goodwill and Other (Details) - USD ($) $ in Thousands | 3 Months Ended | 12 Months Ended
--- | --- | ---
Mar. 31, 2016 | Dec. 31, 2016 | Dec. 31, 2015
Goodwill [Roll Forward] |  |  |
Goodwill period start | $ 524,100 | $ 524,100 | $ 528,600
Accumulated impairment loss period start | (28,200) | (28,200) | (28,200)
Goodwill, net period start | 495,948 | 495,948 | 500,400
Goodwill, Acquired During Period |  | 100 | 0
Goodwill, Impairment Loss |  | 13,500 | 0
Currency fluctuations |  | (5,400) | (4,500)
Goodwill period end |  | 518,800 | 524,100
Accumulated impairment loss period end |  | (41,700) | (28,200)
Goodwill, net period end |  | 477,115 | 495,948
Life Science [Member] |  |  |
Goodwill [Roll Forward] |  |  |
Goodwill period start | 207,200 | 207,200 | 207,700
Accumulated impairment loss period start | (27,200) | (27,200) | (27,200)
Goodwill, net period start | 180,000 | 180,000 | 180,500
Goodwill, Acquired During Period |  | 100 | 0
Goodwill, Impairment Loss |  | 0 | 0
Currency fluctuations |  | (200) | (500)
Goodwill period end |  | 207,100 | 207,200
Accumulated impairment loss period end |  | (27,200) | (27,200)
Goodwill, net period end |  | 179,900 | 180,000
Clinical Diagnostics [Member] |  |  |
Goodwill [Roll Forward] |  |  |
Goodwill period start | 316,900 | 316,900 | 320,900
Accumulated impairment loss period start | (1,000) | (1,000) | (1,000)
Goodwill, net period start | 315,900 | 315,900 | 319,900
Goodwill, Acquired During Period |  | 0 | 0
Goodwill, Impairment Loss |  | 13,500 | 0
Currency fluctuations |  | (5,200) | (4,000)
Goodwill period end |  | 311,700 | 316,900
Accumulated impairment loss period end |  | (14,500) | (1,000)
Goodwill, net period end |  | $ 297,200 | $ 315,900
Analytical Flow Cytometer Platform [Member] |  |  |
Goodwill [Roll Forward] |  |  |
Goodwill, Acquired During Period | $ 100 |  |

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- Definition Amount after accumulated impairment loss of an asset representing future economic benefits arising from other assets acquired in a business combination that are not individually identified and separately recognized. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 350 -SubTopic 20 -Section 50 -Paragraph 1 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=35741047&loc=d3e13816-109267 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 350 -SubTopic 20 -Section 45 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=6388280&loc=d3e13770-109266 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 350 -SubTopic 20 -Section 45 -Paragraph 5 -URI http://asc.fasb.org/extlink&oid=64834752&loc=SL49117168-202975 + Details
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