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4. Intangible Assets, Goodwill and Other (Tables) | 12 Months Ended
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Dec. 31, 2016
Goodwill and Intangible Assets Disclosure [Abstract] |
Changes to goodwill by segment | Changes to goodwill by segment were as follows (in millions):
|  | 2016 |  |  | 2015
|  | Life Science |  | Clinical Diagnostics |  | Total |  |  | Life Science |  | Clinical Diagnostics |  | Total
Balances as of January 1: |  |  |  |  |  |  |  |  |  |  |  |  |
Goodwill |  | $ | 207.2 |  |  | $ | 316.9 |  |  | $ | 524.1 |  |  |  | $ | 207.7 |  |  | $ | 320.9 |  |  | $ | 528.6 |
Accumulated impairment losses and write-offs |  | (27.2 | ) |  | (1.0 | ) |  | (28.2 | ) |  |  | (27.2 | ) |  | (1.0 | ) |  | (28.2 | )
Goodwill, net |  | 180.0 |  |  | 315.9 |  |  | 495.9 |  |  |  | 180.5 |  |  | 319.9 |  |  | 500.4 |
Acquisitions |  | 0.1 |  |  | — |  |  | 0.1 |  |  |  | — |  |  | — |  |  | — |
Impairment |  | — |  |  | (13.5 | ) |  | (13.5 | ) |  |  | — |  |  | — |  |  | — |
Currency fluctuations |  | (0.2 | ) |  | (5.2 | ) |  | (5.4 | ) |  |  | (0.5 | ) |  | (4.0 | ) |  | (4.5 | )
Balances as of December 31: |  |  |  |  |  |  |  |  |  |  |  |  |
Goodwill |  | 207.1 |  |  | 311.7 |  |  | 518.8 |  |  |  | 207.2 |  |  | 316.9 |  |  | 524.1 |
Accumulated impairment losses and write-offs |  | (27.2 | ) |  | (14.5 | ) |  | (41.7 | ) |  |  | (27.2 | ) |  | (1.0 | ) |  | (28.2 | )
Goodwill, net |  | $ | 179.9 |  |  | $ | 297.2 |  |  | $ | 477.1 |  |  |  | $ | 180.0 |  |  | $ | 315.9 |  |  | $ | 495.9 |
Schedule of Finite-Lived Intangible Assets by Major-Class | Information regarding our identifiable purchased intangible assets with definite and indefinite lives is as follows (in millions):
| December 31, 2016
| Average Remaining Life (years) |  | Purchase Price |  | Accumulated Amortization |  | Net Carrying Amount
Customer relationships/lists | 1-8 |  | $ | 84.4 |  |  | $ | (52.8 | ) |  | $ | 31.6 |
Know how | 1-9 |  | 182.6 |  |  | (136.9 | ) |  | 45.7 |
Developed product technology | 3-12 |  | 125.9 |  |  | (56.3 | ) |  | 69.6 |
Licenses | 1-9 |  | 39.0 |  |  | (30.6 | ) |  | 8.4 |
Tradenames | 4-8 |  | 3.5 |  |  | (2.5 | ) |  | 1.0 |
Covenants not to compete | 2-9 |  | 7.8 |  |  | (2.5 | ) |  | 5.3 |
Total definite-lived intangible assets |  |  | 443.2 |  |  | (281.6 | ) |  | 161.6 |
In-process research and development |  |  | — |  |  | — |  |  | — |
Total purchased intangible assets |  |  | $ | 443.2 |  |  | $ | (281.6 | ) |  | $ | 161.6 |
| December 31, 2015
| Average Remaining Life (years) |  | Purchase Price |  | Accumulated Amortization |  | Net Carrying Amount
Customer relationships/lists | 2-10 |  | $ | 84.7 |  |  | $ | (46.8 | ) |  | $ | 37.9 |
Know how | 1-10 |  | 184.0 |  |  | (121.6 | ) |  | 62.4 |
Developed product technology | 4-12 |  | 101.3 |  |  | (48.9 | ) |  | 52.4 |
Licenses | 3-10 |  | 39.2 |  |  | (28.5 | ) |  | 10.7 |
Tradenames | 5-9 |  | 3.5 |  |  | (2.4 | ) |  | 1.1 |
Covenants not to compete | 3-7 |  | 4.8 |  |  | (1.7 | ) |  | 3.1 |
Total definite-lived intangible assets |  |  | 417.5 |  |  | (249.9 | ) |  | 167.6 |
In-process research and development |  |  | 46.4 |  |  | — |  |  | 46.4 |
Total purchased intangible assets |  |  | $ | 463.9 |  |  | $ | (249.9 | ) |  | $ | 214.0 |

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