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4. Intangible Assets, Goodwill and Other (Tables) | 12 Months Ended
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Dec. 31, 2017
Goodwill and Intangible Assets Disclosure [Abstract] |
Changes to goodwill by segment | Changes to goodwill by segment were as follows (in millions):
|  | 2017 |  |  | 2016
|  | Life Science |  | Clinical Diagnostics |  | Total |  |  | Life Science |  | Clinical Diagnostics |  | Total
Balances as of January 1: |  |  |  |  |  |  |  |  |  |  |  |  |
Goodwill |  | $ | 207.1 |  |  | $ | 311.7 |  |  | $ | 518.8 |  |  |  | $ | 207.2 |  |  | $ | 316.9 |  |  | $ | 524.1 |
Accumulated impairment losses and write-offs |  | (27.2 | ) |  | (14.5 | ) |  | (41.7 | ) |  |  | (27.2 | ) |  | (1.0 | ) |  | (28.2 | )
Goodwill, net |  | 179.9 |  |  | 297.2 |  |  | 477.1 |  |  |  | 180.0 |  |  | 315.9 |  |  | 495.9 |
Acquisitions |  | 26.2 |  |  | — |  |  | 26.2 |  |  |  | 0.1 |  |  | — |  |  | 0.1 |
Impairment |  | (8.7 | ) |  | (2.8 | ) |  | (11.5 | ) |  |  | — |  |  | (13.5 | ) |  | (13.5 | )
Currency fluctuations |  | 1.4 |  |  | 12.9 |  |  | 14.3 |  |  |  | (0.2 | ) |  | (5.2 | ) |  | (5.4 | )
Balances as of December 31: |  |  |  |  |  |  |  |  |  |  |  |  |
Goodwill |  | 234.7 |  |  | 324.6 |  |  | 559.3 |  |  |  | 207.1 |  |  | 311.7 |  |  | 518.8 |
Accumulated impairment losses and write-offs |  | (35.9 | ) |  | (17.3 | ) |  | (53.2 | ) |  |  | (27.2 | ) |  | (14.5 | ) |  | (41.7 | )
Goodwill, net |  | $ | 198.8 |  |  | $ | 307.3 |  |  | $ | 506.1 |  |  |  | $ | 179.9 |  |  | $ | 297.2 |  |  | $ | 477.1 |
Schedule of Finite-Lived Intangible Assets by Major-Class | Information regarding our identifiable purchased intangible assets with definite lives is as follows (in millions):
| December 31, 2017
| Average Remaining Life (years) |  | Purchase Price |  | Accumulated Amortization |  | Net Carrying Amount
Customer relationships/lists | 1-7 |  | $ | 92.3 |  |  | $ | (64.4 | ) |  | $ | 27.9 |
Know how | 1-8 |  | 194.9 |  |  | (157.9 | ) |  | 37.0 |
Developed product technology | 1-12 |  | 133.3 |  |  | (70.3 | ) |  | 63.0 |
Licenses | 1-12 |  | 76.7 |  |  | (36.0 | ) |  | 40.7 |
Tradenames | 1-6 |  | 3.9 |  |  | (3.0 | ) |  | 0.9 |
Covenants not to compete | 1-8 |  | 7.9 |  |  | (3.3 | ) |  | 4.6 |
Total definite-lived intangible assets |  |  | $ | 509.0 |  |  | $ | (334.9 | ) |  | $ | 174.1 |
| December 31, 2016
| Average Remaining Life (years) |  | Purchase Price |  | Accumulated Amortization |  | Net Carrying Amount
Customer relationships/lists | 1-8 |  | $ | 84.4 |  |  | $ | (52.8 | ) |  | $ | 31.6 |
Know how | 1-9 |  | 182.6 |  |  | (136.9 | ) |  | 45.7 |
Developed product technology | 3-12 |  | 125.9 |  |  | (56.3 | ) |  | 69.6 |
Licenses | 1-9 |  | 39.0 |  |  | (30.6 | ) |  | 8.4 |
Tradenames | 4-8 |  | 3.5 |  |  | (2.5 | ) |  | 1.0 |
Covenants not to compete | 2-9 |  | 7.8 |  |  | (2.5 | ) |  | 5.3 |
Total definite-lived intangible assets |  |  | $ | 443.2 |  |  | $ | (281.6 | ) |  | $ | 161.6 |

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- Definition Tabular disclosure of the characteristics, including initial carrying value, residual amount, weighted average useful life, of finite-lived intangible assets acquired during the period by major class. A major class is composed of intangible assets that can be grouped together because they are similar, either by nature or by their use in the operations of the company. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 350 -SubTopic 30 -Section 50 -Paragraph 1 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=66006027&loc=d3e16265-109275 + Details
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