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4. Goodwill and other Purchased Intangible Assets Intangible Assets, Goodwill and Other Intangible Assets (Details) - USD ($)
$ in Thousands
 3 Months Ended 12 Months Ended
Mar. 31, 2016
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Feb. 15, 2017
Jan. 06, 2016
Acquired Finite-Lived Intangible Assets [Line Items]            
Finite-Lived Intangible Assets, Gross   $ 509,000 $ 443,200      
Future Amortization Expense, Year One   28,400        
Future Amortization Expense, Year Two   25,000        
Future Amortization Expense, Year Three   22,900        
Future Amortization Expense, Year Four   22,100        
Future Amortization Expense, Year Five   18,000        
Finite-Lived Intangible Assets, Amortization Expense, after Year Five   57,700        
Finite-Lived Intangible Assets, Net [Abstract]            
Accumulated Amortization   (334,900) (281,600)      
Net Carrying Amount   174,100 161,600      
Amortization [Abstract]            
Amortization expense   30,800 35,200 $ 36,500    
Impairment losses on goodwill and long-lived assets   11,506 62,305 $ 0    
Impairment of Intangible Assets, Indefinite-lived (Excluding Goodwill)     46,400      
Intangible Assets, Net (Excluding Goodwill)   174,113 161,609      
Customer Relationships [Member]            
Acquired Finite-Lived Intangible Assets [Line Items]            
Finite-Lived Intangible Assets, Gross   92,300 84,400      
Finite-Lived Intangible Assets, Net [Abstract]            
Accumulated Amortization   (64,400) (52,800)      
Net Carrying Amount   27,900 31,600      
Know how [Member]            
Acquired Finite-Lived Intangible Assets [Line Items]            
Finite-Lived Intangible Assets, Gross   194,900 182,600      
Finite-Lived Intangible Assets, Net [Abstract]            
Accumulated Amortization   (157,900) (136,900)      
Net Carrying Amount   37,000 45,700      
Developed Technology Rights [Member]            
Acquired Finite-Lived Intangible Assets [Line Items]            
Finite-Lived Intangible Assets, Gross   133,300 125,900      
Finite-Lived Intangible Assets, Net [Abstract]            
Accumulated Amortization   (70,300) (56,300)      
Net Carrying Amount   63,000 69,600      
Licensing Agreements [Member]            
Acquired Finite-Lived Intangible Assets [Line Items]            
Finite-Lived Intangible Assets, Gross   76,700 39,000      
Finite-Lived Intangible Assets, Net [Abstract]            
Accumulated Amortization   (36,000) (30,600)      
Net Carrying Amount   40,700 8,400      
Trade Names [Member]            
Acquired Finite-Lived Intangible Assets [Line Items]            
Finite-Lived Intangible Assets, Gross   3,900 3,500      
Finite-Lived Intangible Assets, Net [Abstract]            
Accumulated Amortization   (3,000) (2,500)      
Net Carrying Amount   900 1,000      
Noncompete Agreements [Member]            
Acquired Finite-Lived Intangible Assets [Line Items]            
Finite-Lived Intangible Assets, Gross   7,900 7,800      
Finite-Lived Intangible Assets, Net [Abstract]            
Accumulated Amortization   (3,300) (2,500)      
Net Carrying Amount   $ 4,600 $ 5,300      
Minimum [Member] | Customer Relationships [Member]            
Acquired Finite-Lived Intangible Assets [Line Items]            
Finite-Lived Intangible Assets, Remaining Amortization Period   1 year 1 year      
Minimum [Member] | Know how [Member]            
Acquired Finite-Lived Intangible Assets [Line Items]            
Finite-Lived Intangible Assets, Remaining Amortization Period   1 year 1 year      
Minimum [Member] | Developed Technology Rights [Member]            
Acquired Finite-Lived Intangible Assets [Line Items]            
Finite-Lived Intangible Assets, Remaining Amortization Period   1 year 3 years      
Minimum [Member] | Licensing Agreements [Member]            
Acquired Finite-Lived Intangible Assets [Line Items]            
Finite-Lived Intangible Assets, Remaining Amortization Period   1 year 1 year      
Minimum [Member] | Trade Names [Member]            
Acquired Finite-Lived Intangible Assets [Line Items]            
Finite-Lived Intangible Assets, Remaining Amortization Period   1 year 4 years      
Minimum [Member] | Noncompete Agreements [Member]            
Acquired Finite-Lived Intangible Assets [Line Items]            
Finite-Lived Intangible Assets, Remaining Amortization Period   1 year 2 years      
Minimum [Member] | Other Intangible Assets [Member]            
Acquired Finite-Lived Intangible Assets [Line Items]            
Finite-Lived Intangible Assets, Remaining Amortization Period   0 years 0 years      
Maximum [Member] | Customer Relationships [Member]            
Acquired Finite-Lived Intangible Assets [Line Items]            
Finite-Lived Intangible Assets, Remaining Amortization Period   7 years 8 years      
Maximum [Member] | Know how [Member]            
Acquired Finite-Lived Intangible Assets [Line Items]            
Finite-Lived Intangible Assets, Remaining Amortization Period   8 years 9 years      
Maximum [Member] | Developed Technology Rights [Member]            
Acquired Finite-Lived Intangible Assets [Line Items]            
Finite-Lived Intangible Assets, Remaining Amortization Period   12 years 12 years      
Maximum [Member] | Licensing Agreements [Member]            
Acquired Finite-Lived Intangible Assets [Line Items]            
Finite-Lived Intangible Assets, Remaining Amortization Period   12 years 9 years      
Maximum [Member] | Trade Names [Member]            
Acquired Finite-Lived Intangible Assets [Line Items]            
Finite-Lived Intangible Assets, Remaining Amortization Period   6 years 8 years      
Maximum [Member] | Noncompete Agreements [Member]            
Acquired Finite-Lived Intangible Assets [Line Items]            
Finite-Lived Intangible Assets, Remaining Amortization Period   8 years 9 years      
Maximum [Member] | Other Intangible Assets [Member]            
Acquired Finite-Lived Intangible Assets [Line Items]            
Finite-Lived Intangible Assets, Remaining Amortization Period   0 years 0 years      
RainDance Technologies, Inc. [Member]            
Acquired Finite-Lived Intangible Assets [Line Items]            
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Finite-Lived Intangibles         $ 37,600  
RainDance Technologies, Inc. [Member] | Developed Technology Rights [Member]            
Acquired Finite-Lived Intangible Assets [Line Items]            
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Finite-Lived Intangibles         1,000  
RainDance Technologies, Inc. [Member] | Licensing Agreements [Member]            
Acquired Finite-Lived Intangible Assets [Line Items]            
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Finite-Lived Intangibles         36,400  
RainDance Technologies, Inc. [Member] | Trade Names [Member]            
Acquired Finite-Lived Intangible Assets [Line Items]            
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Finite-Lived Intangibles         $ 200  
Analytical Flow Cytometer Platform [Member]            
Acquired Finite-Lived Intangible Assets [Line Items]            
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Finite-Lived Intangibles           $ 32,700
Analytical Flow Cytometer Platform [Member] | Developed Technology Rights [Member]            
Acquired Finite-Lived Intangible Assets [Line Items]            
Finite-lived Intangible Assets Acquired $ 29,700          
Analytical Flow Cytometer Platform [Member] | Noncompete Agreements [Member]            
Acquired Finite-Lived Intangible Assets [Line Items]            
Finite-lived Intangible Assets Acquired $ 3,000