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10. Segment Information (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2018
Sep. 30, 2017
Sep. 30, 2018
Sep. 30, 2017
Segment Reporting Information [Line Items]        
Net sales $ 545,138 $ 534,141 $ 1,672,568 $ 1,538,858
Income before income taxes 350,131 30,588 1,553,906 51,855
Life Science [Member]        
Segment Reporting Information [Line Items]        
Net sales 206,600 192,700 622,200 546,500
Income before income taxes 10,200 5,300 25,700 (36,400)
Clinical Diagnostics [Member]        
Segment Reporting Information [Line Items]        
Net sales 334,000 338,000 1,038,800 982,300
Income before income taxes 22,400 30,300 86,800 90,400
All Other Segments [Member]        
Segment Reporting Information [Line Items]        
Net sales 4,500 3,400 11,600 10,100
Income before income taxes $ 100 $ 200 $ 100 $ 600