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4. Goodwill and other Purchased Intangible Assets Intangible Assets, Goodwill and Other (Details) - USD ($) $ in Thousands | 3 Months Ended | 12 Months Ended
--- | --- | ---
Mar. 31, 2018 | Mar. 31, 2017 | Dec. 31, 2018 | Dec. 31, 2017
Goodwill [Line Items] |  |  |  |
Goodwill, Written off Related to Sale of Business Unit |  |  | $ (1,400) |
Goodwill [Roll Forward] |  |  |  |
Goodwill period start | $ 559,300 | $ 518,800 | 559,300 | $ 518,800
Accumulated impairment loss period start | (53,200) | (41,700) | (53,200) | (41,700)
Goodwill, net period start | 506,069 | 477,100 | 506,069 | 477,100
Goodwill, Acquired During Period |  |  | 0 | 26,200
Goodwill, Purchase Accounting Adjustments |  |  |  | 0
Goodwill, Impairment Loss |  |  | 282,000 | 11,500
Currency fluctuations |  |  | (2,900) | 14,300
Goodwill period end |  |  | 555,000 | 559,300
Accumulated impairment loss period end |  |  | (335,200) | (53,200)
Goodwill, net period end |  |  | 219,770 | 506,069
Life Science [Member] |  |  |  |
Goodwill [Roll Forward] |  |  |  |
Goodwill period start | 234,700 | 207,100 | 234,700 | 207,100
Accumulated impairment loss period start | (35,900) | (27,200) | (35,900) | (27,200)
Goodwill, net period start | 198,800 | 179,900 | 198,800 | 179,900
Goodwill, Acquired During Period |  |  | 0 | 26,200
Goodwill, Purchase Accounting Adjustments |  |  | 0 | 0
Goodwill, Impairment Loss |  |  | 5,900 | 8,700
Currency fluctuations |  |  | (200) | 1,400
Goodwill period end |  |  | 234,500 | 234,700
Accumulated impairment loss period end |  |  | (41,800) | (35,900)
Goodwill, net period end |  |  | 192,700 | 198,800
Clinical Diagnostics [Member] |  |  |  |
Goodwill [Line Items] |  |  |  |
Goodwill, Written off Related to Sale of Business Unit | (1,400) |  | (1,400) |
Goodwill [Roll Forward] |  |  |  |
Goodwill period start | 324,600 | 311,700 | 324,600 | 311,700
Accumulated impairment loss period start | (17,300) | (14,500) | (17,300) | (14,500)
Goodwill, net period start | $ 307,300 | 297,200 | 307,300 | 297,200
Goodwill, Acquired During Period |  |  | 0 | 0
Goodwill, Purchase Accounting Adjustments |  |  |  | 0
Goodwill, Impairment Loss |  |  | 276,100 | 2,800
Currency fluctuations |  |  | (2,700) | 12,900
Goodwill period end |  |  | 320,500 | 324,600
Accumulated impairment loss period end |  |  | (293,400) | (17,300)
Goodwill, net period end |  |  | 27,100 | $ 307,300
RainDance Technologies, Inc. [Member] |  |  |  |
Goodwill [Roll Forward] |  |  |  |
Goodwill, Acquired During Period |  | $ 26,200 |  |
Pasteur Sanofi Diagnosics S.A. [Member] | Clinical Diagnostics [Member] |  |  |  |
Goodwill [Roll Forward] |  |  |  |
Goodwill, Impairment Loss |  |  | 18,100 |
DiaMed [Member] | Clinical Diagnostics [Member] |  |  |  |
Goodwill [Roll Forward] |  |  |  |
Goodwill, Impairment Loss |  |  | 247,200 |
Biotest AG [Member] | Clinical Diagnostics [Member] |  |  |  |
Goodwill [Roll Forward] |  |  |  |
Goodwill, Impairment Loss |  |  | $ 10,800 |

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