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4. Intangible Assets, Goodwill and Other (Tables) | 12 Months Ended
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Dec. 31, 2018
Goodwill and Intangible Assets Disclosure [Abstract] |
Changes to goodwill by segment | Changes to goodwill by segment were as follows (in millions):
|  | 2018 |  |  | 2017
|  | Life Science |  | Clinical Diagnostics |  | Total |  |  | Life Science |  | Clinical Diagnostics |  | Total
Balances as of January 1: |  |  |  |  |  |  |  |  |  |  |  |  |
Goodwill |  | $ | 234.7 |  |  | $ | 324.6 |  |  | $ | 559.3 |  |  |  | $ | 207.1 |  |  | $ | 311.7 |  |  | $ | 518.8 |
Accumulated impairment losses and write-offs |  | (35.9 | ) |  | (17.3 | ) |  | (53.2 | ) |  |  | (27.2 | ) |  | (14.5 | ) |  | (41.7 | )
Goodwill, net |  | 198.8 |  |  | 307.3 |  |  | 506.1 |  |  |  | 179.9 |  |  | 297.2 |  |  | 477.1 |
Acquisitions |  | — |  |  | — |  |  | — |  |  |  | 26.2 |  |  | — |  |  | 26.2 |
Divestiture |  | — |  |  | (1.4 | ) |  | (1.4 | ) |  |  | — |  |  | — |  |  | — |
Impairment |  | (5.9 | ) |  | (276.1 | ) |  | (282.0 | ) |  |  | (8.7 | ) |  | (2.8 | ) |  | (11.5 | )
Currency fluctuations |  | (0.2 | ) |  | (2.7 | ) |  | (2.9 | ) |  |  | 1.4 |  |  | 12.9 |  |  | 14.3 |
Balances as of December 31: |  |  |  |  |  |  |  |  |  |  |  |  |
Goodwill |  | 234.5 |  |  | 320.5 |  |  | 555.0 |  |  |  | 234.7 |  |  | 324.6 |  |  | 559.3 |
Accumulated impairment losses and write-offs |  | (41.8 | ) |  | (293.4 | ) |  | (335.2 | ) |  |  | (35.9 | ) |  | (17.3 | ) |  | (53.2 | )
Goodwill, net |  | $ | 192.7 |  |  | $ | 27.1 |  |  | $ | 219.8 |  |  |  | $ | 198.8 |  |  | $ | 307.3 |  |  | $ | 506.1 |
Schedule of Finite-Lived Intangible Assets by Major-Class | Information regarding our identifiable purchased intangible assets with definite lives is as follows (in millions):
| December 31, 2018
| Average Remaining Life (years) |  | Purchase Price |  | Accumulated Amortization |  | Net Carrying Amount
Customer relationships/lists | 1-6 |  | $ | 88.7 |  |  | $ | (68.3 | ) |  | $ | 20.4 |
Know how | 1-7 |  | 190.6 |  |  | (159.8 | ) |  | 30.8 |
Developed product technology | 1-10 |  | 130.4 |  |  | (86.6 | ) |  | 43.8 |
Licenses | 7-11 |  | 76.3 |  |  | (40.9 | ) |  | 35.4 |
Tradenames | 2-6 |  | 3.9 |  |  | (3.3 | ) |  | 0.6 |
Covenants not to compete | 7 |  | 3.2 |  |  | (1.1 | ) |  | 2.1 |
Total definite-lived intangible assets |  |  | $ | 493.1 |  |  | $ | (360.0 | ) |  | $ | 133.1 |
| December 31, 2017
| Average Remaining Life (years) |  | Purchase Price |  | Accumulated Amortization |  | Net Carrying Amount
Customer relationships/lists | 1-7 |  | $ | 92.3 |  |  | $ | (64.4 | ) |  | $ | 27.9 |
Know how | 1-8 |  | 194.9 |  |  | (157.9 | ) |  | 37.0 |
Developed product technology | 1-12 |  | 133.3 |  |  | (70.3 | ) |  | 63.0 |
Licenses | 1-12 |  | 76.7 |  |  | (36.0 | ) |  | 40.7 |
Tradenames | 1-6 |  | 3.9 |  |  | (3.0 | ) |  | 0.9 |
Covenants not to compete | 1-8 |  | 7.9 |  |  | (3.3 | ) |  | 4.6 |
Total definite-lived intangible assets |  |  | $ | 509.0 |  |  | $ | (334.9 | ) |  | $ | 174.1 |

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