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4. Intangible Assets, Goodwill and Other (Tables) | 12 Months Ended
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Dec. 31, 2019
Goodwill and Intangible Assets Disclosure [Abstract] |
Changes to goodwill by segment | Changes to goodwill by segment were as follows (in millions):
|  | 2019 |  |  | 2018
|  | Life Science |  | Clinical Diagnostics |  | Total |  |  | Life Science |  | Clinical Diagnostics |  | Total
Balances as of January 1: |  |  |  |  |  |  |  |  |  |  |  |  |
Goodwill |  | $ | 234.5 |  |  | $ | 320.5 |  |  | $ | 555.0 |  |  |  | $ | 234.7 |  |  | $ | 324.6 |  |  | $ | 559.3 |
Accumulated impairment losses and write-offs |  | (41.8 | ) |  | (293.4 | ) |  | (335.2 | ) |  |  | (35.9 | ) |  | (17.3 | ) |  | (53.2 | )
Goodwill, net |  | 192.7 |  |  | 27.1 |  |  | 219.8 |  |  |  | 198.8 |  |  | 307.3 |  |  | 506.1 |
Acquisitions |  | 15.6 |  |  | 28.7 |  |  | 44.3 |  |  |  | — |  |  | — |  |  | — |
Divestiture |  | — |  |  | — |  |  | — |  |  |  | — |  |  | (1.4 | ) |  | (1.4 | )
Impairment |  | — |  |  | — |  |  | — |  |  |  | (5.9 | ) |  | (276.1 | ) |  | (282.0 | )
Currency fluctuations |  | — |  |  | — |  |  | — |  |  |  | (0.2 | ) |  | (2.7 | ) |  | (2.9 | )
Balances as of December 31: |  |  |  |  |  |  |  |  |  |  |  |  |
Goodwill |  | 250.1 |  |  | 349.2 |  |  | 599.3 |  |  |  | 234.5 |  |  | 320.5 |  |  | 555.0 |
Accumulated impairment losses and write-offs |  | (41.8 | ) |  | (293.4 | ) |  | (335.2 | ) |  |  | (41.8 | ) |  | (293.4 | ) |  | (335.2 | )
Goodwill, net |  | $ | 208.3 |  |  | $ | 55.8 |  |  | $ | 264.1 |  |  |  | $ | 192.7 |  |  | $ | 27.1 |  |  | $ | 219.8 |
Schedule of Finite-Lived Intangible Assets by Major-Class | Information regarding our identifiable purchased intangible assets with definite and indefinite lives is as follows (in millions):
| December 31, 2019
| Weighted-Average Amortization Period (years) |  | Purchase Price |  | Accumulated Amortization |  | Net Carrying Amount
Customer relationships/lists | 6.36 |  | $ | 107.2 |  |  | $ | (74.3 | ) |  | $ | 32.9 |
Know how | 5.71 |  | 188.5 |  |  | (162.6 | ) |  | 25.9 |
Developed product technology | 8.31 |  | 144.2 |  |  | (93.9 | ) |  | 50.3 |
Licenses | 8.74 |  | 76.0 |  |  | (44.4 | ) |  | 31.6 |
Tradenames | 8.50 |  | 6.4 |  |  | (3.6 | ) |  | 2.8 |
Covenants not to compete | 6.01 |  | 3.2 |  |  | (1.4 | ) |  | 1.8 |
Other | — |  | 0.1 |  |  | (0.1 | ) |  | — |
Total definite-lived intangible assets |  |  | 525.6 |  |  | (380.3 | ) |  | 145.3 |
In-process research and development |  |  | 0.2 |  |  | — |  |  | 0.2 |
Total purchased intangible assets |  |  | $ | 525.8 |  |  | $ | (380.3 | ) |  | $ | 145.5 |
| December 31, 2018
| Weighted-Average Amortization Period (years) |  | Purchase Price |  | Accumulated Amortization |  | Net Carrying Amount
Customer relationships/lists | 3.98 |  | $ | 88.7 |  |  | $ | (68.3 | ) |  | $ | 20.4 |
Know how | 6.64 |  | 190.6 |  |  | (159.8 | ) |  | 30.8 |
Developed product technology | 8.34 |  | 130.4 |  |  | (86.6 | ) |  | 43.8 |
Licenses | 9.72 |  | 76.3 |  |  | (40.9 | ) |  | 35.4 |
Tradenames | 3.42 |  | 3.9 |  |  | (3.3 | ) |  | 0.6 |
Covenants not to compete | 7.01 |  | 3.2 |  |  | (1.1 | ) |  | 2.1 |
Total definite-lived intangible assets |  |  | $ | 493.1 |  |  | $ | (360.0 | ) |  | $ | 133.1 |

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