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4. Intangible Assets, Goodwill and Other
12 Months Ended
Dec. 31, 2020
Goodwill and Intangible Assets Disclosure [Abstract]  
Goodwill and Intangible Assets Disclosure
4.    GOODWILL AND OTHER PURCHASED INTANGIBLE ASSETS

Changes to goodwill by segment were as follows (in millions):
 20202019
Life
Science
Clinical
Diagnostics
TotalLife
Science
Clinical
Diagnostics
Total
Balances as of January 1:      
Goodwill$250.1 $349.2 $599.3 $234.5 $320.5 $555.0 
Accumulated impairment losses and write-offs(41.8)(293.4)(335.2)(41.8)(293.4)(335.2)
Goodwill, net208.3 55.8 264.1 192.7 27.1 219.8 
Acquisitions (see Note 2)29.8 — 29.8 15.6 28.7 44.3 
Other adjustments (see Note 2)(2.0)— (2.0)— — — 
Period increase, net27.8 — 27.8 15.6 28.7 44.3 
Balances as of December 31:      
Goodwill277.9 349.2 627.1 250.1 349.2 599.3 
Accumulated impairment losses and write-offs(41.8)(293.4)(335.2)(41.8)(293.4)(335.2)
Goodwill, net$236.1 $55.8 $291.9 $208.3 $55.8 $264.1 


Information regarding our identifiable purchased intangible assets with definite and indefinite lives is as follows (in millions):
December 31, 2020
Weighted-Average Amortization Period (years)Purchase
Price
Accumulated
Amortization
Net
Carrying
Amount
Customer relationships/lists5.51$116.6 $(87.2)$29.4 
Know how4.75196.6 (175.4)21.2 
Developed product technology14.00218.1 (107.1)111.0 
Licenses7.7365.6 (37.4)28.2 
Tradenames7.826.6 (4.2)2.4 
Covenants not to compete3.874.5 (2.0)2.5 
Other0.1 (0.1)— 
     Total definite-lived intangible assets608.1 (413.4)194.7 
In-process research and development4.8 — 4.8 
     Total purchased intangible assets$612.9 $(413.4)$199.5 
 December 31, 2019
Weighted-Average Amortization Period (years)Purchase
Price
Accumulated
Amortization
Net
Carrying
Amount
Customer relationships/lists6.36$107.2 $(74.3)$32.9 
Know how5.71188.5 (162.6)25.9 
Developed product technology8.31144.2 (93.9)50.3 
Licenses8.7476.0 (44.4)31.6 
Tradenames8.506.4 (3.6)2.8 
Covenants not to compete6.013.2 (1.4)1.8 
Other0.1 (0.1)— 
Total definite-lived intangible assets 525.6 (380.3)145.3 
In-process research and development0.2 — 0.2 
Total purchased intangible assets$525.8 $(380.3)$145.5 

No impairment losses related to goodwill and purchased intangibles were recorded in 2020 and 2019.

Amortization expense related to purchased intangible assets for the years ended December 31, 2020, 2019 and 2018 was $27.5 million, $23.5 million and $28.3 million, respectively.  Estimated future amortization expense (based on existing purchased intangible assets) for the years ending December 31, 2021, 2022, 2023, 2024, 2025 and thereafter is $28.3 million, $25.1 million, $23.8 million, $20.7 million, $18.7 million, and $78.1 million, respectively.